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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Study reveals 45% drop in oxycodone use in Australia after policy changes

Between 2018 and 2020, Australia implemented policy changes to improve the quality and safety of opioid prescribing, with a specific focus on oxycodone.

12 Sep 2024

SCIEX summit - Highlighting scientific breakthroughs in mass spectrometry that really count

Join scientists and researchers from around the globe to discuss the importance of LC-MS in fields like food and environmental testing, pharmaceutical and biopharmaceutical discovery and development and biomedical and omics research.

From SCIEX 9 Sep 2024

New study finds skincare products could expose children to harmful phthalates

Children's skincare products are linked to urinary phthalate levels.

9 Sep 2024

Fish gut bacteria may provide new ingredients for skincare

There are some pretty strange ingredients in cosmetics and skin care products. One example is snail mucin -; also known as snail slime -; which is used for its moisturizing and antioxidant properties.

5 Sep 2024

AI tool RENAISSANCE transforms creation of kinetic models in cellular metabolism

Understanding how cells process nutrients and produce energy - collectively known as metabolism - is essential in biology. However, analyzing the vast amounts of data on cellular processes to determine metabolic states is a complex task.

30 Aug 2024

Marijuana use linked to elevated nicotine levels in plastic surgery patients

Marijuana use is common among patients considering plastic surgery and is associated with elevated nicotine levels on laboratory tests, reports a paper in the September issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

29 Aug 2024

Targeting cancer cells by cutting off essential nutrients and backup supplies

Cancer cells have voracious appetites. And there are certain nutrients they can't live without. Scientists have long hoped they might stop tumors in their tracks by cutting off an essential part of cancer cells' diet.

28 Aug 2024

How diet shapes gut microbiota and affects brain function

Researchers discuss the diet-microbiota-gut-brain axis, which describes the role of both diet and gut microbiota composition on cognitive and emotional health.

26 Aug 2024

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Study identifies phenylacetylglutamine (PAGln), a gut microbiome metabolite, as a novel allosteric modulator of β2-adrenergic receptors, offering insights into its role in cardiovascular disease (CVD) risk.

26 Aug 2024

Immune cells' two-pronged approach to maintaining acetyl-CoA reserves

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists.

23 Aug 2024

Common fatty acid could improve treatment of recurrent bacterial vaginosis infections

Researchers investigated oleic acid as a potential treatment to inhibit Lactobacillus iners dominance in bacterial vaginosis.

22 Aug 2024

How persistent organic pollutants affect gut health: findings on metabolic disruptions and microbiota changes

Early life exposure to potent AHR agonists on gut microbiota and its potential effects on metabolic health later in life.

20 Aug 2024

Metabolomics links increased heme iron intake to increased insulin-independent type 2 diabetes risk

Researchers utilie metabolomics to investigate the processes underlying dietary heme iron consumption and the risk of type 2 diabetes.

20 Aug 2024

Study uncovers oleic acid's role in restoring vaginal microbial balance in bacterial vaginosis

More than half of women globally experience bacterial vaginosis (BV) -; an imbalance of naturally occurring microbes in the female genital tract -; at least once in their life.

19 Aug 2024

Scientists discover key age-related biological shifts at 40 and 60

Researchers uncover the nonlinear dynamics of aging, revealing significant biological shifts at ages 40 and 60, offering new insights into age-related diseases.

16 Aug 2024

Diet-derived molecules identified as main drivers of young-onset colorectal cancer risk

A new Cleveland Clinic study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat.

14 Aug 2024

Ketogenic diet can boost efficacy of pancreatic cancer therapy

A study of fasting and the ketogenic diet reveals a new vulnerability of pancreatic tumors to an existing cancer drug.

14 Aug 2024

Can odors help fight infection? Nematode research suggests so

Researchers from the University of California, Berkeley, used the nematode model Caenorhabditis elegans to determine whether the olfactory nervous system could non-autonomously control the mitochondrial unfolded protein response in response to cellular stress.

12 Aug 2024

Omega-3 fatty acids show potential in protecting brain health in older adults

Researchers assess the role of ω-3 polyunsaturated fatty acids (PUFAs) in reducing white matter lesion accumulation and neuronal integrity degeneration.

6 Aug 2024

The real cost of processed foods: How Western diets are harming global health

A recent study in Nature Medicine reviews the adverse effects of Western diets on human health, highlighting increased risks of chronic diseases and gut dysbiosis. Researchers call for global awareness and promotion of healthier dietary patterns.