Metabolites News and Research

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Research findings provide new avenues to target virus infection

Viral infection is one of the leading medical challenges of the 21st Century, ranging from the Hepatitis C Virus (HCV) epidemic affecting 3% of the global population, to recent outbreaks of West Nile, Zika, and Ebola viruses.

12 Oct 2016

New non-invasive method could improve diagnosis of severe liver disease

A new non-invasive method of predicting the risk of developing a severe form of liver disease could ensure patients receive early and potentially life-saving medical intervention before irreversible damage is done.

6 Oct 2016

New lab-on-a-chip system can detect effects of toxic substances on hemoglobin in blood

A new lab-on-a-chip system, developed by the University of Twente in The Netherlands, is capable of fast analysis of the effects of toxic substances on hemoglobin, for example. It mimicks human metabolism.

4 Oct 2016

Maternal serum levels of nicotinamide linked to child’s risk of atopic eczema

Infants whose mothers had a higher level of a particular type of vitamin B during pregnancy have a lower risk of eczema at age 12 months, new Southampton research has shown.

23 Sep 2016

Crick researchers find promising target for new tuberculosis drugs

Scientists led by Dr Luiz Pedro Carvalho at the Francis Crick Institute in London have found a promising new target in the search for new tuberculosis drugs. In the process, they say they've proven the strengths of a new research technique called metabolomics.

20 Sep 2016

Oral antidiabetic drug modulates the body's nitrogen and urea metabolism

The most frequently prescribed oral antidiabetic drug metformin significantly affects metabolic pathways.

14 Sep 2016

Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

In a novel controlled clinical trial, participants in a six-day Ayurvedic-based well-being program that featured a vegetarian diet, meditation, yoga and massages experienced measurable decreases in a set of blood-based metabolites associated with inflammation, cardiovascular disease risk and cholesterol regulation.

9 Sep 2016

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder.

6 Sep 2016

ToMMo scientists identify genetic variants affecting enzymatic activities in healthy people

Scientists from Tohoku University's Tohoku Medical Megabank Organization have published research about genetic diversity and metabolome in Scientific Reports.

1 Sep 2016

Foul smelling gas could help people with diabetes recover from heart complications

A gas that was formerly known for its noxious qualities could help people with diabetes recover from common heart and blood vessel complications, concludes research led by the University of Exeter Medical School.

1 Sep 2016

UTHealth scientists discover powerful predictors of congestive heart failure

A team of scientists at The University of Texas Health Science Center at Houston and Baylor College of Medicine, led by Eric Boerwinkle, Ph.D., Richard Gibbs, Ph.D., and Bing Yu, Ph.D., have identified powerful predictors of congestive heart failure, a major cause of hospitalization and death in the United States.

31 Aug 2016

Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

Whitehead Institute scientists have developed a method to quickly isolate and systematically measure metabolite concentrations within the cellular organelles known as mitochondria, often referred to as the "powerhouses of the cell."

31 Aug 2016

CFS possesses objectively identifiable chemical signature in men and women, study reveals

Dauer is the German word for persistence or long-lived. It is a type of stasis in the development in some invertebrates that is prompted by harsh environmental conditions. The findings are published online in the August 29 issue of PNAS.

29 Aug 2016

Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders, according to research led by Jorge Henao-Mejia, MD, PhD, an assistant professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania.

25 Aug 2016

U-M study casts doubt on possible link between obesity and imbalance of microbes

For people with weight problems, news headlines in recent years may have brought relief, as researchers studying the microscopic creatures inside our bodies reported possible links between obesity and an out-of-whack balance of microbes.

23 Aug 2016

Umbilical cells from babies of obese mothers show impaired expression of vital genes regulating metabolism

Scientists have long known that infants born to women who are obese show higher risks of obesity, but they don't fully understand what boosts those risks.

23 Aug 2016

Seeds of tropical shrub guarana contain ten times more amount of catechins than green tea

The millions of people who consume green tea all over the world benefit from the catechins it contains.

22 Aug 2016

Novel marine natural product appears to reduce pancreatic tumor size

Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound.

18 Aug 2016

Treating metabolic abnormalities may improve symptoms in patients with treatment-resistant depression

Identifying and treating metabolic deficiencies in patients with treatment-resistant depression can improve symptoms and in some cases even lead to remission, according to new research from the University of Pittsburgh School of Medicine published online today in the American Journal of Psychiatry.

12 Aug 2016

Pancreatic cancer cells find alternative source of nutrition to avoid starvation

Pancreatic cancer cells avert starvation in dense tumors by ordering nearby support cells to supply them with an alternative source of nutrition.

11 Aug 2016