Methionine News and Research

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Mediomics receives additional $460,000 in STTR Phase II grant for PINCER protein assay development

Mediomics, LLC has received an additional $460,000 in a renewal of its 2nd year STTR Phase II grant (R42GM079891) from the National Institute of General Medical Sciences. Since 2007, Mediomics has received over one million dollars of STTR funding to develop its quick and sensitive homogenous PINCER™ protein assay. The major goal of the second year project is to further increase the sensitivity of the biosensor.

28 Jul 2010

Benefits of drug L-methionine for neurogenic bladder disorders unclear

It is unclear whether patients with neurogenic bladder disorders benefit from the drug L-methionine. The only study currently available provides neither proof of benefit nor proof of harm. This is the result of a report published by the German Institute for Quality and Efficiency in Health Care (IQWiG) on 12 July 2010.

20 Jul 2010

People with high levels of vitamin B6 and methionine less likiely to develop lung cancer

People with higher blood levels of vitamin B6 and the amino acid methionine appear to have a lower risk of lung cancer, a French study has found. But more research is needed to understand if higher levels of the nutrients directly protect against the disease.

3 Jul 2010

Data on MetAP2 inhibitors for treatment of obesity presented at ADA 2010

Zafgen, Inc., a pharmaceutical company pioneering novel obesity therapeutics to help the body regain and sustain a lean, healthy state by targeting imbalances in fat metabolism, today announced data on ZGN-201, a prototype methionine aminopeptidase 2 inhibitor, for the treatment of obesity. Preclinical studies demonstrate MetAP2 inhibition eliminates excess body weight through the regulation of fat metabolism and food intake, and normalizes glucose tolerance in animal models.

28 Jun 2010

High vitamin B levels in blood reduce lung cancer risk: Study

Regular intake of Vitamin B complex can reduce the risk of getting lung cancer, researchers have found. The research paper in the Journal of the American Medical Association however emphasized that quitting smoking was the best method to reduce the risk of lung cancer. It is too early to say that vitamin supplements can actually prevent lung cancer say researchers. Lung cancer kills nearly 1.3 million people globally each year according to the World Health Organization and 10 to 15 percent of smokers develop lung cancer.

15 Jun 2010

Two variants of LPA gene associated with increased risk of coronary heart disease

Celera Corporation and its collaborators at the University of California at San Francisco today announced the publication of a paper confirming the association of an increased risk of coronary heart disease (CHD) and two variants of the LPA gene. The two LPA single nucleotide polymorphisms (SNPs) are Ile4399Met, a polymorphism in the protease-like domain of LPA, and rs10455872, a SNP located in a non-coding region of the LPA gene.

9 Jun 2010

Switching to healthier diet can slow or reverse cognitive impairment in patients with Alzheimer's Disease: Study

Patients in the early to moderate stages of Alzheimer's Disease could have their cognitive impairment slowed or even reversed by switching to a healthier diet, according to researchers at Temple University.

9 Jun 2010

Study: MetAP inhibitors prevent TB growth in test tubes

Suspecting that a particular protein in tuberculosis was likely to be vital to the bacteria's survival, Johns Hopkins scientists screened 175,000 small chemical compounds and identified a potent class of compounds that selectively slows down this protein's activity and, in a test tube, blocks TB growth, demonstrating that the protein is indeed a vulnerable target.

25 Mar 2010

High methionine diet may increase risk of dementia

A diet rich in methionine, an amino acid typically found in red meats, fish, beans, eggs, garlic, lentils, onions, yogurt and seeds, can possibly increase the risk of developing Alzheimer's disease, according to a study by Temple researchers.

17 Dec 2009

Vitamins and nutriceuticals improve memory and cognitive performance, shows study

A recent study presented at the Gerontological Society of America's 62nd Annual Scientific Meeting shows that a combination of vitamins and nutriceuticals improves memory and cognitive performance in community-dwelling adults.

8 Dec 2009

New study helps understand the positive effect of dietary restriction on healthy ageing

A new study of the Max Planck Institute for Biology of Ageing could help to understand the positive effect of dietary restriction on healthy ageing.

5 Dec 2009

Cells protect themselves against viruses and bacteria with novel non-genetic mechanism

When cells are confronted with an invading virus or bacteria or exposed to an irritating chemical, they protect themselves by going off their DNA recipe and inserting the wrong amino acid into new proteins to defend them against damage, scientists have discovered.

26 Nov 2009

How men and women cope differently with stress traced to genetic differences

Can people's differing reactions to situations of stress be attributed at least in part to genetic differences and do those differences affect men and women in different ways - with the edge seemingly favoring the women? Research conducted at the Hebrew University of Jerusalem would seem to indicate that the answer to both questions is yes.

5 Apr 2009

In lung cancer, silencing one crucial gene disrupts normal functioning of genome

While examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism.

1 Jan 2009

Vitamin B deficiency may cause vascular cognitive impairment

A deficiency of B-vitamins may cause vascular cognitive impairment, according to a new study. Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University used an experimental model to examine the metabolic, cognitive, and microvascular effects of dietary B-vitamin deficiency.

2 Sep 2008

FDA approves new formulation of genetically engineered version of Factor VIIa plasma protein

The U.S. Food and Drug Administration today approved a new formulation of the genetically engineered version of Factor VIIa, a plasma protein essential for the clotting of blood. The new formulation allows the product to be stored at room temperature (up to 81 degrees Fahrenheit) for up to two years.

9 May 2008

Methionine News and Research

Mediomics receives additional $460,000 in STTR Phase II grant for PINCER protein assay development

Benefits of drug L-methionine for neurogenic bladder disorders unclear

People with high levels of vitamin B6 and methionine less likiely to develop lung cancer

Data on MetAP2 inhibitors for treatment of obesity presented at ADA 2010

High vitamin B levels in blood reduce lung cancer risk: Study

Two variants of LPA gene associated with increased risk of coronary heart disease

Switching to healthier diet can slow or reverse cognitive impairment in patients with Alzheimer's Disease: Study

Study: MetAP inhibitors prevent TB growth in test tubes

High methionine diet may increase risk of dementia

Vitamins and nutriceuticals improve memory and cognitive performance, shows study

New study helps understand the positive effect of dietary restriction on healthy ageing

Cells protect themselves against viruses and bacteria with novel non-genetic mechanism

How men and women cope differently with stress traced to genetic differences

In lung cancer, silencing one crucial gene disrupts normal functioning of genome

Vitamin B deficiency may cause vascular cognitive impairment

FDA approves new formulation of genetically engineered version of Factor VIIa plasma protein

Study identifies new mechanism linking activation of key heart enzyme and oxidative stress

Device allows scientists to control gene activity across generations of cells

New control mechanism for genetic code translation discovered in bacteria

Variant of COMT gene linked to impulsive decisions

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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