Methylphenidate News and Research

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Researchers gain new insights into ADHD drug's mechanism of action

For decades, doctors have treated kids with attention-deficit/hyperactivity disorder (ADHD) with methylphenidate, a stimulant drug sold as Ritalin and Concerta, making it one of the most widely prescribed medications aimed at the central nervous system.

8 Dec 2022

Noradrenergic drugs could be repurposed to offer effective treatment for Alzheimer's disease symptoms

There is "good evidence" that drugs to treat attention deficit hyperactivity disorder (ADHD) might also successfully treat key aspects of Alzheimer's disease, finds a pooled data analysis of the available research, published online in the Journal of Neurology Neurosurgery & Psychiatry.

6 Jul 2022

Caffeine could be a therapeutic arsenal to alleviate some of the ADHD symptoms

Attention Deficit Hyperactivity Disorder, or ADHD, is a psychiatric pathology for which diagnosis has increased exponentially over the last 20 years.

29 Mar 2022

Study examines the effects of methylphenidate on mental fatigue in multiple sclerosis patients

A team of researchers at Kessler Foundation studied the effects of methylphenidate on mental fatigue in individuals with multiple sclerosis (MS). This is the first study to examine the psychostimulant's effects on 'state' vs 'trait' mental fatigue in MS.

18 Dec 2021

Noramco Announces Submission of Drug Master File for Lisdexamfetamine Dimesylate ─ Active Pharmaceutical Ingredient

Leading Producer of Controlled Substance APIs Now Supplying Lisdex API to Generic Drug Manufacturers Preparing for the 2023 Patent Expiry of Top-Selling Branded ADHD Therapy.

3 Dec 2021

Study reveals potential therapeutic target to tackle ADHD and impulsivity

A study published in the journal Pharmacological Research describes the existence of a complex built by dopamine and noradrenergic receptors that could be a therapeutic target of potential interest to tackle the attention deficit hyperactivity disorder (ADHD) and impulsivity.

23 Sep 2021

ADHD medications may lower suicide risk in children with hyperactivity, behavioral disorders

ADHD medications may lower suicide risk in children with hyperactivity, oppositional defiance and other behavioral disorders, according to new research from the Lifespan Brain Institute (LiBI) of Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania.

7 Jun 2021

ADHD medications may decrease suicidality risk in certain children

ADHD medications may lower suicide risk in children with hyperactivity, oppositional defiance and other behavioral disorders, according to new research from the Lifespan Brain Institute of Children's Hospital of Philadelphia and the University of Pennsylvania.

5 Jun 2021

Researchers discover new brain circuit that may help fight obesity

Like a good story, feeding has a beginning, a middle and an end. It begins with appetite prompting the search for food, continues with eating the food and it ends when satiation hits and the consumption of food is stopped.

27 May 2021

Study analyzes two different classes of drugs in a large group of preschoolers with ADHD

In a multi-institutional study, researchers in the Developmental-Behavioral Pediatrics Research Network (DBPNet), led by Children's Hospital of Philadelphia (CHOP), have conducted the first and largest analysis to date comparing the effectiveness and side effects of stimulants like methylphenidate (Ritalin) and alpha-adrenergic agonists like guanfacine (Tenex) in preschool-age children.

5 May 2021

Poisoning exposures appear to be increasing in Australian schools

New research from the University of Sydney has found poisoning exposures in children and adolescents while at school are relatively common and appear to be increasing, highlighting the need for more robust prevention measures.

3 Nov 2020

Insufficient evidence for cognitive efficacy of drug treatments in multiple sclerosis

Researchers at Kessler Foundation conducted a comprehensive review of pharmacologic agents used in the treatment of multiple sclerosis, seeking evidence for efficacy for the cognitive dysfunction experienced by more than half of affected individuals.

17 Jun 2020

How Ritalin works: focus on benefits rather than costs of work

A new study published in the journal Science shows that brain stimulant drugs like Ritalin, often used to treat concentration problems in conditions like attention deficit hyperactivity disorder (ADHD), work in a different way than commonly thought.

19 Mar 2020

Children diagnosed with ADHD less likely to take medication consistently

Children diagnosed with ADHD inconsistently take their prescribed medication, going without treatment 40 per cent of the time, a new study has found.

3 Feb 2020

Researchers identify how certain areas of the brain respond to ADHD drug

Attention-deficit hyperactivity disorder is a neurobiological disorder characterized by symptoms of hyperactivity, inattention and impulsivity.

17 Jan 2020

Study looks at effects of Ritalin on children with ADHD

When children with ADHD don't respond well to Methylphenidate (MPH, also known as Ritalin) doctors often increase the dose.

9 Sep 2019

MRI scans show how ADHD medication affects brain structure in children

MRI scans have revealed that children taking the medication methylphenidate experience alterations in the distribution of white matter in the brain.

15 Aug 2019

Expanding scope of stimulants to better treat attention deficit hyperactivity disorder

A comprehensive new review of the expanding scope of stimulants available to treat attention deficit hyperactivity disorder serves as a valuable guide to clinicians as they choose from among the many new drug formulations and technologies available to treat this complex disorder.

22 May 2019

Study suggests HLD200 could provide novel, more flexible alternative to treating ADHD

A new three-part study showed that a delayed-release, extended-release form of methylphenidate could be given to adults in the evening with or without food and would not exert any clinically meaningful effect for at least 10 hours after administration.

2 Apr 2019

ADHD drug raising risk of psychosis

A new study has found that teenagers and youngsters who are treated with amphetamines such as Adderall are at a greater risk of developing psychosis compared to patients who are on other drugs such as Ritalin. The results of the study were published in the latest issue of the New England Journal of Medicine.

21 Mar 2019