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Gene sequencing explains why natural bioremediation 'bug' has big appetite for chlorinated pollutants

"The born-to-dechlorinate bug" is what Cornell University researchers called Dehalococcoides ethenogenes Strain 195 when they found the bacterium obligingly detoxifying the pollutant PCE, or perchloroethylene (a chlorinated solvent used for dry cleaning), in sludge from an Ithaca, N.Y., sewage treatment plant.

6 Jan 2005

Genomics tools provide clues to what causes 400 million cases of gastrointestinal disease each year

In a study that could benefit medical and food-safety research, scientists have used comparative genomics tools to find clues about why some strains of the bacterium Campylobacter – which each year cause more than 400 million cases of gastrointestinal disease – are more virulent than others.

4 Jan 2005

Evidence suggests that changes in the bacteria and fungi in the gastrointestinal tract can intensify the immune system's reaction to common allergens

If you want to avoid allergies or asthma, scientists at the University of Michigan Medical School suggest you start paying more attention to what's in your gut.

23 Dec 2004

Key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease

Virginia Commonwealth University scientists have made a key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease, a finding that could lead to a vaccine against the tick-borne illness that affects thousands of people each year.

16 Dec 2004

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Vaccinating large populations of white-footed mice against the bacterium that causes Lyme disease could help reduce the risk of transmission of the disease to humans, says a study supported by the National Institute of Allergy and Infectious Diseases (NIAID).

14 Dec 2004

Celebrex like gene suppresses the growth of colon cancer

Cancer researchers at the Case Western Reserve University (Case) School of Medicine, University Hospitals of Cleveland (UHC) and the Howard Hughes Medical Institute have found a "Celebrex-like" gene that suppresses the growth of colon cancer.

13 Dec 2004

Using precise, radioactively labeled genetic probes, researchers study cancer gene activity from outside the body

Using precise, radioactively labeled genetic probes, researchers at Jefferson Medical College have seen cancer gene activity from outside the body in laboratory mice. The probes, which work by attaching to genetic codes copied from an active cancer gene, may someday aid physicians and scientists in cancer detection and in determining the appropriate treatment for a cancer.

13 Dec 2004

Key molecular signal allows malarial parasites to target human red blood cells

Northwestern University researchers have identified a key molecular "signal" that allows malarial parasites to release virulence proteins inside human red blood cells.

13 Dec 2004

Animal model helps explain how AIDS virus spreads throughout the body following oral exposure

Researchers at UT Southwestern Medical Center at Dallas have utilized an animal model to trace how the virus that causes AIDS in humans may enter and spread throughout the body following an oral exposure.

3 Dec 2004

Why our immune system worsens with age

Scientists at the Vaccine and Gene Therapy Institute at Oregon Health & Science University have made a discovery that helps explain why our immune system worsens with age. The work was led by Janko Nikolich-Zugich, M.D., Ph.D., a senior scientist at the VGTI.

2 Dec 2004

Potential vaccine for the deadly toxin ricin

A potential vaccine for the deadly toxin ricin, a "Category B" biological agent, will enter the first phase of clinical testing in coming weeks at UT Southwestern Medical Center at Dallas.

30 Nov 2004

Salmonella pathogen uses molecular hydrogen to grow and become virulent

New research, headed by microbiologists from the University of Georgia, show for the first time that Salmonella – a widespread and often deadly bacterial pathogen – use molecular hydrogen to grow and become virulent.

29 Nov 2004

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004

Research shows that even bacteria don't put their eggs in one basket

Diversification helps reduce overall risk by putting your eggs in more than one basket and is a strategy that strengthens groups of all kinds -- from forests challenged with environmental stress to stock market portfolios in uncertain times. Findings from University of Iowa researchers show that even bacteria have learned this important lesson.

16 Nov 2004

Link between immune protein and longer survival in melanoma patients

Immune responses to prevent or delay the spread of melanoma, a deadly form of skin cancer, are more likely to prolong survival in patients if their immune cells carry a special kind of marker on the surface, according to a team of researchers at the University of Virginia Health System.

5 Nov 2004

Long-term safety of transplanted pig cells to humans confirmed

Living Cell Technologies Limited has published a paper in the November issue of the Journal of Clinical Microbiology which demonstrates the long-term safety of transplanted insulin-producing pig islets in people with type 1 diabetes.

4 Nov 2004

Gene regulated by need to process proteins linked to enlargement of protein processing factory

Part of a cellular mechanism that regulates the folding of new proteins into their proper shapes also includes a genetic response that enlarges the factory where both protein folding and packaging of proteins occurs.

2 Nov 2004

Easy-to-make vaccine tackles a range of illnesses

Australian researchers have created a totally synthetic vaccine that is effective against viruses, harmful bacteria and tumours and could lead to a powerful new arsenal of vaccines for humans and animals.

26 Oct 2004

Transplanted human retinal stem cells can successfully regenerate

"We transplanted the cells early in the animals' development when all the nutrients and signals they needed for differentiation were still there," says lead author Brenda Coles, a U of T laboratory technician working under the supervision of Professor Derek van der Kooy in the Department of Medical Genetics and Microbiology. "When their eyes fully developed, the human cells survived, migrated into the sensory part of the eye and formed the correct cells."

25 Oct 2004

Study could lead to new, more effective treatments for urinary tract infections

Anyone who thinks scientists lead a glamorous, exciting life should talk to Jennifer Snyder, a graduate student at the University of Maryland’s School of Medicine.

25 Oct 2004

Microbiology News and Research

Gene sequencing explains why natural bioremediation 'bug' has big appetite for chlorinated pollutants

Genomics tools provide clues to what causes 400 million cases of gastrointestinal disease each year

Evidence suggests that changes in the bacteria and fungi in the gastrointestinal tract can intensify the immune system's reaction to common allergens

Key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Celebrex like gene suppresses the growth of colon cancer

Using precise, radioactively labeled genetic probes, researchers study cancer gene activity from outside the body

Key molecular signal allows malarial parasites to target human red blood cells

Animal model helps explain how AIDS virus spreads throughout the body following oral exposure

Why our immune system worsens with age

Potential vaccine for the deadly toxin ricin

Salmonella pathogen uses molecular hydrogen to grow and become virulent

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Research shows that even bacteria don't put their eggs in one basket

Link between immune protein and longer survival in melanoma patients

Long-term safety of transplanted pig cells to humans confirmed

Gene regulated by need to process proteins linked to enlargement of protein processing factory

Easy-to-make vaccine tackles a range of illnesses

Transplanted human retinal stem cells can successfully regenerate

Study could lead to new, more effective treatments for urinary tract infections

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