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Simulating an overactive autoimmune response leads to changes in the brain region

Researchers at the University of Tsukuba in Japan show that simulating an overactive autoimmune response in mice leads to changes in the hippocampal region of the brain.

17 Feb 2021

Study finds locations of early prion protein accumulation in the eye

The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes of Health scientists.

29 Jan 2021

Microglial cells contribute to the negative mood experienced during neurological diseases

Special immune cells found in the brain, microglia, play a key role in the processes that make you feel uneasy and depressed in correlation with inflammation.

26 Jan 2021

Study: Oligodendrocytes play key role in the distribution of energy-rich molecules

The human brain has about as many neurons as glial cells. These are divided into four major groups: the microglia, the astrocytes, the NG2 glial cells, and the oligodendrocytes.

19 Jan 2021

Timing may be critical when administering treatment after brain injury

Researchers from the National Institutes of Health have discovered Jekyll and Hyde immune cells in the brain that ultimately help with brain repair but early after injury can lead to fatal swelling, suggesting that timing may be critical when administering treatment.

18 Jan 2021

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant's intestinal lining, is often connected to the development of severe brain injury in those infants who survive.

6 Jan 2021

Researchers discover novel therapeutic strategy for ischemic stroke using experimental model

Research conducted at LSU Health New Orleans Neuroscience Center of Excellence reports that a combination of an LSU Health-patented drug and selected DHA derivatives is more effective in protecting brain cells and increasing recovery after stroke than a single drug. The findings are published in Brain Circulation, available here.

4 Jan 2021

Brain damage is not caused by direct COVID-19 attack, indicates study

n an in-depth study of how COVID-19 affects a patient's brain, National Institutes of Health researchers consistently spotted hallmarks of damage caused by thinning and leaky brain blood vessels in tissue samples from patients who died shortly after contracting the disease.

3 Jan 2021

Researchers find mechanism underlying plasticity in adult brains

Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while connections deemed unnecessary are pruned away.

24 Dec 2020

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Researchers at the Kobe University Graduate School of Medicine have revealed that alterations in fetal microglia resulting from maternal inflammation could contribute towards the onset of developmental and psychiatric disorders.

23 Dec 2020

Trinity team uncovers mutations linked with early onset dementia

Scientists at Trinity College Dublin today announced a significant advance in our understanding of an early onset form of dementia that may also progress our understanding of conditions such as Alzheimer's disease.

22 Dec 2020

Brain tissue analysis may help explain enduring mysteries about PTSD

A post-mortem analysis of brain tissue from people who had been diagnosed with post-traumatic stress disorder (PTSD) may help explain enduring mysteries about the disorder, such as why women are more susceptible to it and whether a dampened immune system response plays a role in dealing with stress, a team headed by Yale University researchers has found.

21 Dec 2020

Microglia News and Research

Simulating an overactive autoimmune response leads to changes in the brain region

Study finds locations of early prion protein accumulation in the eye

Microglial cells contribute to the negative mood experienced during neurological diseases

Study: Oligodendrocytes play key role in the distribution of energy-rich molecules

Timing may be critical when administering treatment after brain injury

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Researchers discover novel therapeutic strategy for ischemic stroke using experimental model

Brain damage is not caused by direct COVID-19 attack, indicates study

Researchers find mechanism underlying plasticity in adult brains

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Trinity team uncovers mutations linked with early onset dementia

Brain tissue analysis may help explain enduring mysteries about PTSD

Detecting SARS-CoV-2 sequences in blood monocytes

Brain protein indicates a link between circadian rhythm dysfunction and Alzheimer's Disease

Microglial surveillance helps prevent seizure activity in the brain

Research reveals insights into potential drivers of 'wet' age-related macular degeneration

Study: Maternal omega-3 deficiency can alter the development of neuronal networks in offspring

Targeting excessive calcium may provide a new way to improve outcomes in stroke patients

Study sheds new light on how diabetes contributes to the development of Alzheimer’s disease

Researchers identify anti-inflammatory mechanisms that drive alcohol addiction

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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