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New research sheds light on future efforts to eradicate HIV from the body in human patients

Where does HIV hide? Antiretroviral drugs can usually control the virus, but can't completely eliminate it. So any strategy to eradicate HIV from the body has to take into account not only the main group of immune cells the virus targets, called CD4 or helper T cells, but other infected cells as well.

3 Nov 2014

Alzheimer's disease report success in harnessing mouse's immune system to attack toxic proteins

Alzheimer's disease experts at NYU Langone Medical Center and elsewhere are reporting success in specifically harnessing a mouse's immune system to attack and remove the buildup of toxic proteins in the brain that are markers of the deadly neurodegenerative disease.

9 Sep 2014

Findings may help develop biomarkers to identify HIV patients at risk of dementia

Since the introduction of the combination anti-retroviral therapy (cART) in the mid-90s, the life expectancy of HIV patients has significantly improved. As a result, long-term complications are becoming more relevant: almost every second HIV patient is affected by neurocognitive disorders, which can lead to dementia.

4 Sep 2014

New mouse model to open door to research on epilepsy, Alzheimer's

University of Utah scientists have developed a genetically engineered line of mice that is expected to open the door to new research on epilepsy, Alzheimer's and other diseases.

22 Aug 2014

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

A type of immune cell widely believed to exacerbate chronic adult brain diseases, such as Alzheimer's disease and multiple sclerosis (MS), can actually protect the brain from traumatic brain injury (TBI) and may slow the progression of neurodegenerative diseases, according to Cleveland Clinic research published today in the online journal Nature Communications.

22 Jul 2014

Researchers identify pathogenic mechanism common to several neurodegenerative diseases

An international team of researchers identified a pathogenic mechanism that is common to several neurodegenerative diseases. The findings suggest that it may be possible to slow the progression of dementia even after the onset of symptoms.

4 Jul 2014

Persons with reduced levels of TREM2 protein at greater risk for neurodegenerative diseases

Persons with reduced levels of the TREM2 protein could be at greater risk of developing neurodegenerative diseases such as Alzheimer's disease or frontotemporal dementia, according to an international study which included the participation of the Universitat Autònoma de Barcelona and the Sant Pau Biomedical Research Institute.

3 Jul 2014

Autism Speaks awards more than $600,000 to scientists pursuing training in translational research

Autism Speaks, the world's leading autism science and advocacy organization, today announced it has awarded more than $600,000 in funding for six promising scientists pursuing academic training in translational research.

28 Jun 2014

Stem cells in outer blood vessel wall appear to involve in brain reaction following stroke

Two years ago, a new type of stem cell was discovered in the brain that has the capacity to form new cells.

28 May 2014

Neuropathic pain features common in knee OA

Enough patients with knee osteoarthritis experience pain with neuropathic characteristics to warrant attempts to diagnose and classify these features, say researchers.

12 May 2014

Researchers develop new ways to prevent repetitive sports related brain injuries

A new study has provided insight into the behavioral damage caused by repeated blows to the head. The research provides a foundation for scientists to better understand and potentially develop new ways to detect and prevent the repetitive sports injuries that can lead to the condition known as chronic traumatic encephalopathy (CTE).

30 Apr 2014

Researchers develop class of drugs to lessen impact of Alzheimer's, Parkinson's

A class of drugs developed to treat immune-related conditions and cancer - including one currently in clinical trials for glioblastoma and other tumors - eliminates neural inflammation associated with dementia-linked diseases and brain injuries, according to UC Irvine researchers.

17 Apr 2014

Study: Ginsenoside Rb1 attenuates neuronal damage following cerebral ischemia

Activated microglia-mediated inflammation promotes neuronal damage under cerebral hypoxic-ischemic conditions, so it is likely that inhibiting hypoxia-induced activation of microglia will alleviate neuronal damage.

7 Apr 2014

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Researchers at the RIKEN Center for Life Science Technologies, in collaboration with Osaka City University and Kansai University of Welfare Sciences, have used functional PET imaging to show that levels of neuroinflammation, or inflammation of the nervous system, are higher in patients with chronic fatigue syndrome than in healthy people.

4 Apr 2014

Study highlights benefits of using multiple injections to treat Sanfilippo syndrome type III B

New insight has been gained into treating an inherited disorder that creates serious neurological and behavioral disabilities in children and usually leads to death in the teen years.

28 Mar 2014

Study points to potential culprit that kills motor neurons in ALS

Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is marked by a cascade of cellular and inflammatory events that weakens and kills vital motor neurons in the brain and spinal cord. The process is complex, involving cells that ordinarily protect the neurons from harm. Now, a new study by scientists in The Research Institute at Nationwide Children's Hospital points to a potential culprit in this good-cell-gone-bad scenario, a key step toward the ultimate goal of developing a treatment.

27 Mar 2014

Microglia News and Research

New research sheds light on future efforts to eradicate HIV from the body in human patients

Alzheimer's disease report success in harnessing mouse's immune system to attack toxic proteins

Findings may help develop biomarkers to identify HIV patients at risk of dementia

New mouse model to open door to research on epilepsy, Alzheimer's

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

Researchers identify pathogenic mechanism common to several neurodegenerative diseases

Persons with reduced levels of TREM2 protein at greater risk for neurodegenerative diseases

Autism Speaks awards more than $600,000 to scientists pursuing training in translational research

Stem cells in outer blood vessel wall appear to involve in brain reaction following stroke

Neuropathic pain features common in knee OA

Researchers develop new ways to prevent repetitive sports related brain injuries

Researchers develop class of drugs to lessen impact of Alzheimer's, Parkinson's

Study: Ginsenoside Rb1 attenuates neuronal damage following cerebral ischemia

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Study highlights benefits of using multiple injections to treat Sanfilippo syndrome type III B

Study points to potential culprit that kills motor neurons in ALS

Study: Dab2 can exhibit neuroprotective effects in Alzheimer's by regulating TGF-β1/SMAD signaling

Scientists uncover how inflammation and lack of oxygen cause brain damage

Cognitive decline in obese diabetic mice can be reversed with regular exercise, surgical removal of belly fat

ACE protein overexpression elevates immune responses and prevents Alzheimer's-like cognitive decline

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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