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Study reveals unexpected variation in genetic code of protist

Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics.

6 Oct 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

Neoadjuvant immunotherapy shows promise in multiple cancer types

Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching the surface of what is possible, according to a review article co-authored by several current and former investigators from the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Kimmel Cancer Center.

28 Sep 2023

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

In some patients, infection with the pandemic virus SARS-CoV-2 can trigger a dangerous immune response in hardened fatty deposits (plaques) lining the heart's largest blood vessels, a new study shows.

28 Sep 2023

HMS researcher to lead $104 million effort to study bacteria and antibiotic resistance

Harvard Medical School researcher Johan Paulsson will lead a multi-institutional $104 million effort to study bacteria and antibiotic resistance, the U.S. Department of Health and Human Services announced today.

27 Sep 2023

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Small and precise: These are the ideal characteristics for CRISPR systems, the Nobel-prize winning technology used to edit nucleic acids like RNA and DNA.

27 Sep 2023

Gene-silencer study could pave the way for novel cancer therapeutics

Deep inside our cells-;each one complete with an identical set of genes-;a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

26 Sep 2023

Bacteriophage cocktail can effectively disrupt Klebsiella pneumoniae biofilms on medical equipment

Researchers investigated whether a cocktail of bacteriophages coding for the depolymerase polysaccharide could effectively disrupt Klebsiella pneumoniae biofilms.

18 Sep 2023

Using sea slug brains to map human brain development

A University of Massachusetts Amherst neuroscientist has been awarded a $3.1 million grant from the National Institute of Neurological Disease and Stroke to advance knowledge on human brain development by using an unusual subject: the brain of the sea slug.

15 Sep 2023

A family of weird proteins hijacks plants’ cellular plumbing

Many of the bacteria that ravage crops and threaten our food supply use a common strategy to cause disease: they inject a cocktail of harmful proteins directly into the plant's cells.

13 Sep 2023

Musashi-2 protein plays key role in the regulation of mass and metabolic processes in skeletal muscle

Researchers from Tokyo Metropolitan University have shown that the protein Musashi-2 (Msi2) plays a key role in the regulation of mass and metabolic processes in skeletal muscle.

11 Sep 2023

Dietary cholesterol and fruit tannins synergistically promote kidney stone formation

Kidney stones (KS), hard crystalline formations that occur within the kidney, are a common condition that affects millions of people worldwide.

11 Sep 2023

Zebrafish study unravels how the brain orchestrates motion

The zebrafish brain, though simpler than its human counterpart, is a complex network of neurons that engage in a ceaseless dance of electrical activity.

8 Sep 2023

World-renowned Diamond Light Source facility to be upgraded through a £500 million investment

A groundbreaking science facility which kickstarted the UK's world leading Covid drug development and has advanced treatments of global health challenges from HIV to malaria and cancer will be upgraded and expanded through a more than £500 million investment, Science and Technology Secretary Michelle Donelan has announced today (Wednesday 6 September).

5 Sep 2023

Scientists develop new technique to study sugars on immune cells

Everyone loves a sweet treat, even our cells. While we typically think of sugar as a component of our diet that gives us energy, sugars are also very important in guiding the activity of our cells.

5 Sep 2023

Targeting the ORAI1 calcium channel could provide new approach to treating oral cancer

An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study published in Science Signaling led by researchers at NYU College of Dentistry.

5 Sep 2023

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers found that short-term intensive fasting enhances the immune function of red blood cells, including their ability to combat SARS-CoV-2, without affecting their oxygen-carrying capacity. The study reveals that this fasting regimen popular in Asia could offer a multifaceted benefit by amplifying the body's defenses without compromising essential functions.

4 Sep 2023

Researchers unravel structure of MCM8/9 enzyme linked to infertility and cancer

Scientific research requires patience. The rewards are not always immediate, and the technology needed does not always exist. Michael A. Trakselis, Ph.D., professor and director of graduate affairs for the Department of Chemistry and Biochemistry at Baylor University, understands this.

29 Aug 2023

New optical signature in magnetic beads could quickly detect contaminants in diagnostic tests

Getting results from a blood test can take anywhere from one day to a week, depending on what a test is targeting. The same goes for tests of water pollution and food contamination.

25 Aug 2023

Researchers discover how proteins regulate 'treadmilling' in cells

Researchers at the Centre for Genomic Regulation (CRG) have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.

25 Aug 2023

Microscope News and Research

Study reveals unexpected variation in genetic code of protist

Parkinson's disease-related neuronal death more likely to occur at night

Neoadjuvant immunotherapy shows promise in multiple cancer types

SARS-CoV-2 virus can trigger dangerous immune response in artery-clogging plaques

HMS researcher to lead $104 million effort to study bacteria and antibiotic resistance

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Gene-silencer study could pave the way for novel cancer therapeutics

Bacteriophage cocktail can effectively disrupt Klebsiella pneumoniae biofilms on medical equipment

Using sea slug brains to map human brain development

A family of weird proteins hijacks plants’ cellular plumbing

Musashi-2 protein plays key role in the regulation of mass and metabolic processes in skeletal muscle

Dietary cholesterol and fruit tannins synergistically promote kidney stone formation

Zebrafish study unravels how the brain orchestrates motion

World-renowned Diamond Light Source facility to be upgraded through a £500 million investment

Scientists develop new technique to study sugars on immune cells

Targeting the ORAI1 calcium channel could provide new approach to treating oral cancer

Intensive fasting boosts red blood cells' immune powers against COVID-19, study finds

Researchers unravel structure of MCM8/9 enzyme linked to infertility and cancer

New optical signature in magnetic beads could quickly detect contaminants in diagnostic tests

Researchers discover how proteins regulate 'treadmilling' in cells

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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