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Microscope technology reveals full-length serotonin receptor structure for first time

A team of researchers from Case Western Reserve University School of Medicine have used Nobel prize-winning microscope technology to see full-length serotonin receptors for the first time.

6 Feb 2018

Harvard scientists identify molecular machinery responsible for dopamine release in the brain

Studied for decades for its critical role in movement control and reward-seeking behaviors, the neurotransmitter dopamine has been the focus of numerous efforts to understand its activity, particularly when it goes awry in disorders such as Parkinson's and addiction.

1 Feb 2018

Super-resolution microscopy provides insights into cells' amazing flexibility

One of today's sharpest imaging tools, super-resolution microscopy, produces sparkling images of what until now has been the blurry interior of cells, detailing not only the cell's internal organs and skeleton, but also providing insights into cells' amazing flexibility.

31 Jan 2018

New projects to develop innovative technologies to address global health challenges

Fifteen projects announced today, 31 January 2018, will develop new healthcare technologies to tackle international health challenges, ranging from the prevention of limb loss by Syrian refugees to faster diagnosis and treatment for parasitic diseases such as malaria.

31 Jan 2018

BitMap and PicoQuant develop sFLIM detection system for advanced medical tissue imaging

Research project hosted at PicoQuant focuses on developing multichannel photon detection methods for biomedical applications.

31 Jan 2018

Scientists gain better understanding of how the intestine repairs itself after injury

Researchers at Baylor College of Medicine, Johns Hopkins University School of Medicine and the University of California, San Francisco have gained new insights into how the small intestine, one of the fastest renewing tissues in the human body, repairs itself after injury caused by intestinal rotavirus infection.

30 Jan 2018

Scientists discover direct physical contact between two key cellular structures

Northwestern Medicine scientists have discovered that two key cellular structures, called mitochondria and lysosomes, come into direct contact with each other in the cell to regulate their respective functions.

27 Jan 2018

Economical Fluorescence Adapter for Stereo Microscopes

An interview with Charles Mazel, President of NIGHTSEA, conducted by Barbara Foster, The Microscopy & Imaging Place, Inc.

From NIGHTSEA 25 Jan 2018

BioAxial receives US patent for new ‘black fluorophore’ technology

BioAxial, a key player in live cell super resolution microscopy, today announces that it has been granted a US patent covering ‘black fluorophore’, a pivotal component of ‘dark tracking’ technology. This patent consolidates BioAxial’s patent portfolio, which already comprises ten patent families. It also strengthens the company’s position as a technology leader in the field of commercial super-resolution imaging modules.

24 Jan 2018

BIST researchers develop new retinal prosthesis to address visual degeneration

A healthy retina contains photoreceptor cells that convert light changes into nerve impulses, which are then carried along the optic nerve to the brain, where they are decoded into images. Diseases such as retinitis pigmentosa cause the photoreceptor cells to stop functioning, while the rest of the eye remains healthy.

24 Jan 2018

Discovery offers fresh perspective on how the brain keeps its balance

As with all things in life, healthy brain function depends on a balance of forces. We think of our brains as active - moving a leg and saying a word are all "active" events.

22 Jan 2018

Scientists uncover proteins in the brain responsible for movement

Researchers in China have uncovered the proteins used by the brain to balance excitation and inhibition, without which humans would not be able to move.

22 Jan 2018

UCLA researchers describe herpes virus structure associated with Kaposi's sarcoma

UCLA researchers have provided the first description of the structure of the herpes virus associated with Kaposi's sarcoma, a type of cancer.

19 Jan 2018

Researchers describe atom-by-atom changes in ALS-linked protein

For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone.

19 Jan 2018

EXD2 enzyme facilitates protein production in mitochondria

Researchers from the Genomic Instability and Cancer Laboratory at Institute for Research in Biomedicine (IRB Barcelona) have identified a key role for EXD2 in protein production in the mitochondria, the cellular organelles responsible for the majority of energy generation.

17 Jan 2018

Scientists develop unique technique to map elasticity of cell components

Scientists at Université de Montréal have developed a unique technique to map, on a scale of milliseconds, the elasticity of the components inside a cell.

17 Jan 2018

Biomedical, Biophysical and Biological Applications of AFM

An interview with Dr. Thomas Mueller, Director of Product Management at Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 10 Jan 2018

General anesthesia may be more complex in its workings than we know now

Associate Professor Bruno van Swinderen from Queensland Brain Institute, University of Queensland with his colleagues have studied the workings of general anesthetics on the brain and found that these agents did more than just put a person to sleep. These findings could pave the way for better and more effective anesthetics they believe. The study was published in the latest issue of the journal Cell Reports.

10 Jan 2018

Choosing The Correct Camera for Fluorescence Microscopy

It is important to select the proper camera for fluorescence microscopy which has high sensitivity and low noise, to avoid photo bleaching your sample. A monochrome camera is also preferred for fluorescence imaging because it does not have a color filter pattern superimposed over the image sensor. Since the microscope’s filter wheel selects which wavelength makes its way to the sensor, a monochrome camera allows equal signal detection on all pixels and increases the overall sensitivity of the camera.

9 Jan 2018

Study identifies how excess fat disrupts heart cells' ability to produce energy

A University of Iowa study has identified how excess fat in the heart, a common feature in diabetes and obesity, can harm the cells' essential ability to produce energy.

5 Jan 2018