Microscopy News and Research

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Cryo-EM helps decode the molecular architecture of a neural transport protein

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter.

6 Jul 2023

Combination of techniques reveals molecular changes in osteoarthritis

Osteoarthritis is the most common degenerative joint disease, affecting 22% of adults over 40 globally. Although the condition has been extensively studied through a medical perspective, the molecular changes associated with osteoarthritis remain unclear.

5 Jul 2023

EPFL scientists develop an innovative method for reconstructing Tau fibrils

EPFL scientists have developed ClearTau, an innovative method and platform for reconstructing aggregates of the protein Tau found in Alzheimer's disease and other neurodegenerative diseases.

4 Jul 2023

New regulatory system discovered in malaria parasite

Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood, and intrinsic parasite cues, via a factor called ApSigma, as identified by a recent study aided by Tokyo Tech's World Research Hub Initiative.

3 Jul 2023

Stalled progress: Enteric infection reduction efforts slowed in 2022 despite pandemic easing

The research paper focuses on the lack of progress in reducing enteric infection incidence in 2022 despite the subsiding influence of the COVID-19 pandemic. It emphasizes the need for collaborative efforts among food stakeholders and regulators to mitigate pathogen contamination during poultry slaughter and prevent contamination of leafy greens.

3 Jul 2023

Insights gained from genetically modified pig heart transplantation

Researchers described a genetically engineered pig cardiac xenotransplantation in a 57-year-old male patient.

3 Jul 2023

Scientists can study neuronal morphology by harnessing the power of AI with Aivia 12

Leica Microsystems, a leader in microscopy and scientific instrumentation, has released version 12 of Aivia, its flagship AI image analysis software.

1 Jul 2023

Spanish researchers develop new immunotherapy combination for liver cancer

Spanish researchers at Cima University of Navarra have developed a new immunotherapy combination that improves efficacy in animal models of hepatocellular carcinoma. This is a proof of concept that lays the foundations for the application of this treatment in patients with the most common liver cancer.

1 Jul 2023

High-res insights into key bacterial enzyme could lead to development of new antibiotics

A team of scientists from around the globe, including those from Trinity College Dublin, has gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.

30 Jun 2023

Myelin can be harmful to axons in multiple sclerosis

Multiple sclerosis (MS) is a serious neurological disease that usually causes permanent disability. Approximately 2.9 million people are affected worldwide, 240,000 in Germany alone.

30 Jun 2023

20 years later: lessons from SARS-CoV-2 inform preparedness against future pandemics

The identification, development, and assessment of medical countermeasures against emerging pathogens.

30 Jun 2023

The epidemiology of the Streptococcus agalactiae bacterium (group B Streptococcus [GBS]) in Southeast Asia

Researchers detected the presence of a Streptococcus agalactiae (group B Streptococcus) sequence type (ST) 283.

30 Jun 2023

Scientists visualize dynamic motion of gene regions on chromosomes

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion.

29 Jun 2023

New method can track the complete activity of proteins in living cells

The genetic plans within our DNA come to functional fruition through proteins, which underlie our bodies' structure and activity.

29 Jun 2023

Cyanotriazole compounds can selectively and rapidly kill trypanosome parasites, study shows

Cyanotriazole compounds are fast-acting topoisomerase II poisons that can selectively and rapidly kill trypanosome parasites that cause Chagas disease and African sleeping sickness, according to a new study.

29 Jun 2023

Scientists discover new way to defeat invisible cancer cells

Modern immunotherapies boost the body's own defenses against cancer. They activate killer T cells of the immune system that can specifically recognize and destroy cancer cells.

23 Jun 2023

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn.

23 Jun 2023

New platform technology bridges the gap between microscopic analysis and multiplex imaging

Researchers at the Ludwig Center at Harvard have developed a platform technology for imaging that enables integration of the methods of microscopic analysis long employed in pathology laboratories with the visualization of multiple molecular markers in individual cells that is now rapidly advancing in research labs.

22 Jun 2023

Brain organoids provide new insights into HSV-1 encephalitis

The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists with the Rajewsky and Landthaler labs and the Organoid Platform at the Max Delbrück Center in Nature Microbiology.

22 Jun 2023

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

In the United States, sickle cell disease affects about 100,000 people and about 2 million Americans carry this genetic mutation.

22 Jun 2023

Microscopy News and Research

Cryo-EM helps decode the molecular architecture of a neural transport protein

Combination of techniques reveals molecular changes in osteoarthritis

EPFL scientists develop an innovative method for reconstructing Tau fibrils

New regulatory system discovered in malaria parasite

Stalled progress: Enteric infection reduction efforts slowed in 2022 despite pandemic easing

Insights gained from genetically modified pig heart transplantation

Scientists can study neuronal morphology by harnessing the power of AI with Aivia 12

Spanish researchers develop new immunotherapy combination for liver cancer

High-res insights into key bacterial enzyme could lead to development of new antibiotics

Myelin can be harmful to axons in multiple sclerosis

20 years later: lessons from SARS-CoV-2 inform preparedness against future pandemics

The epidemiology of the Streptococcus agalactiae bacterium (group B Streptococcus [GBS]) in Southeast Asia

Scientists visualize dynamic motion of gene regions on chromosomes

New method can track the complete activity of proteins in living cells

Cyanotriazole compounds can selectively and rapidly kill trypanosome parasites, study shows

Scientists discover new way to defeat invisible cancer cells

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

New platform technology bridges the gap between microscopic analysis and multiplex imaging

Brain organoids provide new insights into HSV-1 encephalitis

U.S. patent granted for novel tool designed to reliably diagnose and monitor sickle cell disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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