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Graphene balloon yields unprecedented images of hydrated protein molecules

A graphene water balloon may soon open up new vistas for scientists seeking to understand health and disease at the most fundamental level.

6 Feb 2014

New super-resolution microscopy method could spot dozens of distinct types of biomolecules

A new microscopy method could enable scientists to generate snapshots of dozens of different biomolecules at once in a single human cell, a team from the Wyss Institute of Biologically Inspired Engineering at Harvard University reported Sunday in Nature Methods.

4 Feb 2014

Virtual Lens series of label-free live cell imaging systems announced by Phasefocus

Phase Focus Ltd (Phasefocus), the company that is revolutionising microscopy and imaging with the Phasefocus Virtual Lens®, announces the availability of the Virtual Lens series of label-free live cell imaging systems.

From Phase Focus Limited 4 Feb 2014

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

Researchers from Virginia Commonwealth University (VCU) Massey Cancer Center have discovered a new signaling pathway in sterile inflammation that could impact the treatment of diseases such as cancer, multiple sclerosis and rheumatoid arthritis.

4 Feb 2014

UC Irvine researchers receive $1.54M for stem cell research

Two UC Irvine research teams will receive $1.54 million to further studies on the fundamental structure and function of stem cells. Their work will aid efforts to treat and cure a range of ailments, from cancer to neurological diseases and injuries.

31 Jan 2014

Researchers gain better understanding of HIV infection through electron microscopy

The human intestinal tract, or gut, is best known for its role in digestion. But this collection of organs also plays a prominent role in the immune system. In fact, it is one of the first parts of the body that is attacked in the early stages of an HIV infection. Knowing how the virus infects cells and accumulates in this area is critical to developing new therapies for the over 33 million people worldwide living with HIV. Researchers at the California Institute of Technology are the first to have utilized high-resolution electron microscopy to look at HIV infection within the actual tissue of an infected organism, providing perhaps the most detailed characterization yet of HIV infection in the gut.

30 Jan 2014

Researchers discover potential treatment for viral infection that causes illnesses in children

Researchers have discovered a potential treatment for a viral infection that causes potentially fatal brain swelling and paralysis in children. The findings also point to possible treatments for related viruses including those that cause "common cold" symptoms.

29 Jan 2014

NIBIB-funded researchers develop microscopic technique to improve Mohs surgery

A common surgery for non-melanoma skin cancer, known as Mohs surgery typically achieves excellent results but can be a long process, as the surgeon successively removes the area of concern until the surrounding tissue is free of cancer.

29 Jan 2014

Therapath signs contract with United Healthcare to provide neuropathology services

Therapath LLC, the leader in comprehensive diagnostic and consultative neuropathology laboratory services, has signed a national contract with United Healthcare, a division of UnitedHealth Group (NYSE: UNH), to provide the pathology analysis for these specialty services.

29 Jan 2014

Phasefocus reports on new ptychography paper published in Nature Scientific Reports

Cell imaging often relies on synthetic or genetic fluorescent labels, to provide contrast which can be far from ideal for imaging cells in their in vivo state. We report on the biological application of a label-free, high contrast microscopy technique known as ptychography, in which the image producing step is transferred from the microscope lens to a high-speed phase retrieval algorithm.

From Phase Focus Limited 28 Jan 2014

Researchers develop novel instruments and software for inspecting food microstructure

Applying imaging techniques to food structure is helping scientists devise ways of improving the quality of processed food. Food's microstructure can explain many of its characteristics—be it cake's sponginess, bread's crispness, cracker's crunchiness or fruits' inner gas and water transport system and even colour. Understanding such microstructure and how it changes during food processing is essential to produce high-quality food.

25 Jan 2014

New techniques simplify current test procedures for developing new medications

When developing new medications, biologists and pharma- cologists test different active ingredients and chemical compounds. The main purpose is to find out how biological cells react to these substances.

24 Jan 2014

Xpert MTB/RIF test quickly detects TB and resistance to rifampicin

A second systematic review of a diagnostic test for tuberculosis (TB) endorsed by the World Health Organisation (WHO), has confirmed the accuracy of the test. The updated review assessing the accuracy of Xpert MTB/RIF includes new studies published since the original Cochrane Review was published in January last year.

22 Jan 2014

Parkin and PINK1 function in vesicular trafficking pathway regulates mitochon-drial quality control

Scientists from the Montreal Neurological Institute and Hospital in Canada have discovered that two genes linked to hereditary Parkinson's disease are involved in the early-stage quality control of mitochondria.

22 Jan 2014

Damon Runyon Cancer Research Foundation awards $2.25M to six innovative young scientists

The Damon Runyon Cancer Research Foundation announced that six scientists with novel approaches to fighting cancer have been named 2014 recipients of the Damon Runyon-Rachleff Innovation Award. The grant of $450,000 over three years is awarded each year to early career scientists whose projects have the potential to significantly impact the prevention, diagnosis and treatment of cancer.

21 Jan 2014

New discovery provides insight into body's rejection process during transplantation

In 2009, the first face transplant was performed at Brigham and Women's Hospital (BWH), and lead surgeon, Dr. Bohdan Pomahac has been pioneering the procedure since.

20 Jan 2014

New imaging technique captures vibrations of proteins, tiny motions critical to human life

Like the strings on a violin or the pipes of an organ, the proteins in the human body vibrate in different patterns, scientists have long suspected.

16 Jan 2014

Researchers develop "smart" hydrogel that can deliver medicine on demand

Researchers at the University of Delaware have developed a "smart" hydrogel that can deliver medicine on demand, in response to mechanical force.

16 Jan 2014

T2HemoStat detection of novel clot behavior could direct therapeutic choices for stroke, heart attack victims

T2 Biosystems, a company developing direct detection products enabling superior diagnostics, announced that scientists from the University of Pennsylvania and T2 Biosystems have published a paper in Blood describing novel clot structure biology detected while testing T2 Bio's T2HemoStat-.

10 Jan 2014

Research findings could affect how drugs are developed to treat autoimmune diseases

Researchers at Johns Hopkins have zoomed in on what is going on at the molecular level when the body recognizes and defends against an attack of pathogens, and the findings, they say, could influence how drugs are developed to treat autoimmune diseases.

8 Jan 2014

Microscopy News and Research

Graphene balloon yields unprecedented images of hydrated protein molecules

New super-resolution microscopy method could spot dozens of distinct types of biomolecules

Virtual Lens series of label-free live cell imaging systems announced by Phasefocus

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

UC Irvine researchers receive $1.54M for stem cell research

Researchers gain better understanding of HIV infection through electron microscopy

Researchers discover potential treatment for viral infection that causes illnesses in children

NIBIB-funded researchers develop microscopic technique to improve Mohs surgery

Therapath signs contract with United Healthcare to provide neuropathology services

Phasefocus reports on new ptychography paper published in Nature Scientific Reports

Researchers develop novel instruments and software for inspecting food microstructure

New techniques simplify current test procedures for developing new medications

Xpert MTB/RIF test quickly detects TB and resistance to rifampicin

Parkin and PINK1 function in vesicular trafficking pathway regulates mitochon-drial quality control

Damon Runyon Cancer Research Foundation awards $2.25M to six innovative young scientists

New discovery provides insight into body's rejection process during transplantation

New imaging technique captures vibrations of proteins, tiny motions critical to human life

Researchers develop "smart" hydrogel that can deliver medicine on demand

T2HemoStat detection of novel clot behavior could direct therapeutic choices for stroke, heart attack victims

Research findings could affect how drugs are developed to treat autoimmune diseases

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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