Mitosis News and Research

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Indiana researcher uses OMX light microscope to image mitosis process

Like a pair of dancers sheathed in blue, two chromosomes take the cell's center stage in this scene from the elegant—and usually perfectly performed—process of mitosis.

22 Apr 2013

Research shows THz pulses destroy skin tissue and increase tumor-suppressing proteins

Terahertz (THz) radiation, a slice of the electromagnetic spectrum that occupies the middle ground between microwaves and infrared light, is rapidly finding important uses in medical diagnostics, security, and scientific research. As scientists and engineers find evermore practical uses for this form of radiation, questions persist about its potential human health risks.

15 Mar 2013

New details about molecular surveillance system that helps detect and correct errors in cell division

Studies led by cell biologist Thomas Maresca at the University of Massachusetts Amherst are revealing new details about a molecular surveillance system that helps detect and correct errors in cell division that can lead to cell death or human diseases. Findings are reported in the current issue of the Journal of Cell Biology.

21 Jan 2013

Susceptibility genes for bovine digital dermatitis found

Researchers have identified genetic variants that influence susceptibility to bovine digital dermatitis, an infectious condition that causes lameness of the hindfoot.

9 Jan 2013

BubR1 and its associated regulators promising targets for aging disorders and cancer

A new series of studies in mouse models by Mayo Clinic researchers uncovered that the aging process is characterized by high rates of whole-chromosome losses and gains in various organs, including heart, muscle, kidney and eye, and demonstrate that reducing these rates slows age-related tissue deterioration and promotes a healthier life span. The findings appear in today's online issue of Nature Cell Biology.

18 Dec 2012

Klerokinesis may prevent some cancers from developing

Researchers at the University of Wisconsin Carbone Cancer Center have discovered a new form of cell division in human cells.

18 Dec 2012

American Association of Anatomist announces winners of Young Investigator Awards

The American Association of Anatomist's (AAA) Young Investigator Awards combine three long-standing AAA awards-Bensley, Herrick, and Mossman-with the Morphological Sciences Award, all recognizing investigators in the early stages of their careers who have made important contributions to biomedical science through their research in cell/molecular biology, developmental biology, comparative neuroanatomy, or the morphological sciences.

12 Dec 2012

Ancient algae may hold key to treating malaria and related parasites

Researchers have discovered that parasites of the Apicomplexa taxon, such as Plasmodium falciparum and Toxoplasma gondii, reproduce within host cells using a structure that evolved from a flagellum.

12 Dec 2012

GeneTex to introduce new Histone H3 antibody

GeneTex, a leading manufacturer of antibodies and antibody-related reagents, is set to launch a new antibody against phosphorylated Histone H3.

11 Dec 2012

UMass Amherst biophysicist receives 2013 Margaret Oakley Dayhoff Award

University of Massachusetts Amherst biophysicist Jenny Ross has won one of the top national honors in her field, the 2013 Margaret Oakley Dayhoff Award, from the Biophysical Society of Rockville, Md. It is given to a woman who has achieved prominence for "substantial contributions to science," while showing very high promise for ideas and leadership in the early stages of her biophysical research career.

3 Oct 2012

Study highlights Nek9 protein as decisive factor in cell division

A study by the Institute for Research in Biomedicine (IRB Barcelona) and the Center for Genomic Regulation (acronym in Catalan CRG) highlights the protein Nek9 as a decisive factor in cell division, a fundamental process for both the development of an organism and tissue maintenance.

22 Aug 2012

Orc1 mutations may explain pathology in manifestations of Meier-Gorlin syndrome

Research published Aug. 1 by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise to a particularly extreme version of dwarfism, small brain size, and other manifestations of abnormal growth which generally characterize that rare condition.

1 Aug 2012

Fusion of FGFR and TACC gene leads to glioblastoma

Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes.

26 Jul 2012

Bioengineers develop microfluidic platform to mechanically confine cancer cells

It's well known in conventional biology that during the process of mammalian cell division, or mitosis, a mother cell divides equally into two daughter cells. But when it comes to cancer, say UCLA researchers, mother cells may be far more prolific.

6 Jul 2012

Researchers identify mechanism by which Zds1 protein regulates key function in mitosis

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have identified the mechanism by which protein Zds1 regulates a key function in mitosis, the process that occurs immediately before cell division.

19 May 2012

Salk scientists' discovery explains how a class of chemotherapy drugs works

The well-being of living cells requires specialized squads of proteins that maintain order. Degraders chew up worn-out proteins, recyclers wrap up damaged organelles, and-most importantly-DNA repair crews restitch anything that resembles a broken chromosome. If repair is impossible, the crew foreman calls in executioners to annihilate a cell. As unsavory as this last bunch sounds, failure to summon them is one aspect of what makes a cancer cell a cancer cell.

12 Mar 2012

Study examines mRNA transcripts in the sperm of fruitflies and humans

It had long been assumed that the human sperm cell's mission in life ended once it had transferred its freight of parental DNA to the egg. More recently however, other components of sperm have been implicated in fertilization, and perhaps even in subsequent embryonic development.

1 Mar 2012

Suppressing STARD9 protein could be a novel strategy to fight cancers

Suppressing a newly identified and characterized protein involved in regulating cell division could be a novel strategy to fight certain cancers because it stops the malignant cells from dividing and causes them to die quickly, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center.

12 Dec 2011

Promising new agent against sarcomas affecting children

MK 1775, a small, selective inhibitor molecule, has been found to be active against many sarcomas when tested by researchers at Moffitt Cancer Center in Tampa, Fla. Their findings, recently appearing in Molecular Cancer Therapeutics, published by the American Association for Cancer Research, suggest that a badly needed new agent against sarcomas - especially sarcomas affecting children - may be at hand.

3 Dec 2011

MK 1775 shows promise against sarcomas

MK 1775, a small, selective inhibitor molecule, has been found to be active against many sarcomas when tested by researchers at Moffitt Cancer Center in Tampa, Fla.

3 Dec 2011