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Research sheds light on important events that may play a role in infertility

Everyone considers sperm to be made exclusively by males. But did you know that females also make sperm? Well, it turns out that females also contribute to what makes a sperm a sperm.

8 Mar 2022

MondoA protein delays cellular senescence and promotes longevity

Researchers from Osaka University show that activation of a protein called MondoA can protect against age-related diseases and cellular changes associated with aging.

6 Mar 2022

A new method to produce complex natural products in amoebae

A research team at the Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute in Jena, Germany has developed a new method to produce complex natural products in amoebae.

4 Mar 2022

Harvard researcher develops new model system to illuminate the fundamentals of aging

Huge amounts of time and money have been devoted to finding treatments for diseases that become more common as we age, like cancer and Alzheimer's.

28 Feb 2022

Deactivation of PLa2g7 gene mimics anti-aging effects of caloric restriction in mice

Deactivation of the gene PLa2g7 partially mimics the anti-aging effects of caloric restriction (CR) in mice, researchers report.

11 Feb 2022

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

In normal cells, electrical voltage patterns provide a blueprint for orderly growth. But with cancer, the opposite happens.

11 Jan 2022

Researchers shed light on an important stage of early human embryogenesis for the first time

Scientists have shed light on an important stage of early embryonic development that has never been fully mapped out in humans before.

29 Nov 2021

Switching from restricted diet to unlimited food could be beneficial for reproduction in later life

Switching from a restricted diet to eating as much as you like could be beneficial for reproduction in later life, according to new research from the University of East Anglia.

24 Nov 2021

Using deductive reasoning based on particle physics' principles in aging research

Aging-US published "Applying deductive reasoning and the principles of particle physics to aging research" which reported that aging research currently lacks a common conceptual framework, and one challenge in establishing it is the fact that aging is a highly complex process.

7 Nov 2021

Taking lessons in molecular therapeutics from earthworms to combat COVID

Scientists were interested in further investigating the defense mechanism of earthworms in an effort to discover therapeutic solutions against SARS-CoV-2.

27 Oct 2021

Washington University receives $7.5 million to support NIH's research on senescent cells

Washington University School of Medicine in St. Louis is joining the National Institutes of Health's new research network focused on the study of senescent cells, a rare and important population of cells that is difficult to study but vital for understanding aging and the diseases of aging, including cancer and neurodegeneration.

20 Oct 2021

New approach to predict the enzyme activity using AI

Without enzymes, an organism would not be able to survive. It is these biocatalysts that facilitate a whole range of chemical reactions, producing the building blocks of the cells. Enzymes are also used widely in biotechnology and in our households, where they are used in detergents, for example.

20 Oct 2021

Study investigates the link between gray matter and white matter neurodegeneration in subjective cognitive decline

Aging-US published "The interplay between gray matter and white matter neurodegeneration in subjective cognitive decline" which reported that subjective cognitive complaints were assessed through 9 questions covering amnestic and non-amnestic cognitive domains. In these authors' cohorts, 123 individuals endorsed from one to six subjective cognitive complaints, while 102 individuals reported zero complaints.

11 Oct 2021

Review explores the role of cellular senescence in lymphoid organ dysfunction and immunosenescence

Aging-US published "Cellular senescence in lymphoid organs and immunosenescence" which reported that immunosenescence is a multi-faceted phenomenon at the root of age-associated immune dysfunction.

5 Oct 2021

MR study finds no causal link between age at menarche or age at menopause and Alzheimer's risk

Aging-US published "The role of age at menarche and age at menopause in Alzheimer's disease: evidence from a bidirectional mendelian randomization study" which reported that the association between endogenous estrogen exposure and Alzheimer's disease remains inconclusive in previous observational studies, and few Mendelian randomization studies have focused on their causality thus far.

5 Oct 2021

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

A review aimed to determine the potential of siRNA as a potential COVID-19 treatment by reviewing the currently available literature.

10 Sep 2021

Green tea extract and cocoa-supplemented diets improve survival rate of aging mice

Aging-US published "Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system" which reported that green tea extract (GTE) and cocoa-supplemented diets significantly improved the survival rate of mice.

1 Sep 2021

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

Aging-US published "The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence" which reported that cellular senescence may be a side effect of chemotherapy and other anti-cancer treatments that may promote inflammation and paracrine secondary senescence in healthy tissues.

31 Aug 2021

Study highlights the robustness of miRNA modulation during aging process

Aging-US published "miRNAs generated from Meg3-Mirg locus are downregulated during aging" which reported that Aging determines a multilevel functional decline and increases the risk for cardiovascular pathologies.

28 Aug 2021

Cognitive function of older adults could be improved through multidomain lifestyle interventions

Aging-US published "Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility trial" which reported that in an outcome assessor-blinded, randomized controlled trial, participants without dementia and with one or more modifiable dementia risk factors, aged 60-79 years, were randomly assigned to the facility-based MI, the home-based MI, or the control group receiving general health advice.