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Patients Medical offers prevention tips for patients during heart health month

Patients Medical, a leading integrative medical center in New York, offers prevention tips for patients during heart health month. William Lee, MD, PhD, FACC, a Metabolic Cardiologist and Director of Cardiology at Patients Medical, has a unique approach to medicine which incorporates both traditional and alternative practices to provide patients complete care. He believes good health starts with good heart health.

20 Jan 2010

TUM biophysicists map changes in energy landscape of zipper-like protein molecule

Biophysicists at TUM, the Technische Universitaet Muenchen, have published the results of single-molecule experiments that bring a higher-resolution tool to the study of protein folding. How proteins arrive at the three-dimensional shapes that determine their essential functions - or cause grave diseases when folding goes wrong - is considered one of the most important and least understood questions in the biological and medical sciences.

20 Jan 2010

Scientists study fruit fly to identify key molecular signal in cancer metastasis

Scientists trying to understand how cancer cells invade healthy tissue have used the fruit fly's metamorphosis from maggot to flying insect as a guide to identify a key molecular signal that may be involved in both processes.

20 Jan 2010

HSF1A stimulates more protein chaperones and reduces protein misfolding

Scientists at Duke University Medical Center have found some compounds that improve a cell's ability to properly "fold" proteins and could lead to promising drugs for degenerative nerve diseases, including Huntington's disease, Alzheimer's disease and Parkinson's disease.

20 Jan 2010

European Patent Office grants a patent for Rexahn Pharmaceuticals' RX-3117

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company commercializing potential best in class oncology and CNS therapeutics, today announced that the European Patent Office has granted a patent for its novel anti-cancer compound, RX-3117.

20 Jan 2010

Microbiologists explain why apples are beneficial for health

Why does an apple a day keep the doctor away? New research published in the open access journal BMC Microbiology contributes to our understanding of why eating apples is good for you.

20 Jan 2010

Novartis obtains exclusive worldwide rights to develop and commercialize Chiasma's TPE technology

Chiasma, Inc., a privately held biopharma company, announced today that it has granted Novartis an option to obtain exclusive worldwide rights to develop and commercialize the Company's Transient Permeability Enhancer (TPE) technology for use with certain related small molecule products either in development or currently marketed by Novartis.

19 Jan 2010

PCI Biotech AS completes second dose group in phase I/II study of Amphinex

PCI Biotech AS ( PCIB.OL) reported today that it has completed the successful treatment of the second dose group in the phase I/II study of its proprietary photosensitiser Amphinex® used in combination with the cytotoxic agent bleomycin in cancer patients.

19 Jan 2010

EMBL-EBI hosts drug discovery database

ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launches today with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new drugs in the clinic.

19 Jan 2010

Boehringer Ingelheim, Priaxon announce collaboration in development of mdm2/p53 inhibitors for cancer

Boehringer Ingelheim and Priaxon entered into a worldwide collaboration to research and develop mdm2/p53 inhibitors for the treatment of cancer. Priaxon is providing its innovative and proprietary small molecule drug discovery expertise which is particularly suited to investigate inhibition of protein-protein interactions. p53 is a human tumor suppressor protein.

18 Jan 2010

Babraham Institute research may lead to new means of making purified T cells

Research from the Babraham Institute, reported today in the Journal of Experimental Medicine, provides new insights into how our immune system produces T cells, a type of white blood cell that is an essential part of the body's immune surveillance system for fighting infection. The findings pave the way for a new means of making purified T cells, which gets over one of many hurdles faced in the use of T cells in regenerative medicine and transplantations, and in addition will open up new avenues of research and applications in drug and toxicity testing in industry.

18 Jan 2010

Need for further studies on clinical characteristics of Intrahepatic Cholangiocarcinoma

Incidence of intrahepatic cholangiocarcinoma (ICC) is increasing worldwide and its prognosis is very poor. Thus, further studies on its clinical characteristics for early detection and on surgical treatment for better prognosis are urgently needed.

18 Jan 2010

New findings reveal tendons play an active role in initiating bone ridge formation

Bones, muscles and tendons work together to provide the perfect balance between stability and movement in the skeleton. Now, Weizmann Institute scientists show that this partnership begins in the embryo, when the bones are still taking shape. The

18 Jan 2010

Race against time to produce artificial blood substitute

The Twilight book trilogy has 'vegetarian' vampires living on animal blood and in the TV series True Blood, Japanese scientists have developed a synthetic blood substitute. However, in the most recent blockbuster movie Daybreakers, vampires suffer a horrific fate when attempting to drink their blood substitute.

18 Jan 2010

Breakthrough discovery could lead to new treatments for a variety of CNS disorders

A breakthrough discovery by scientists at the University of Kentucky could someday lead to new treatments for a variety of diseases of the brain, spinal cord and the eye.

18 Jan 2010

Researchers discover how cells flatten out as they adhere to internal bodily surfaces

Researchers at the University of Illinois at Chicago College of Medicine have discovered how cells in the body flatten out as they adhere to internal bodily surfaces, the first step in a wide range of important processes including clot formation, immune defense, wound healing, and the spread of cancer cells.

18 Jan 2010

Research reveals gene activation is linked to most aggressive type of brain cancer

Glioblastoma (GBM), the brain cancer better known for having killed Senator Ted Kennedy a few months ago, is the most aggressive and lethal of all brain tumours.

18 Jan 2010

M. D. Anderson researchers discover mechanism that helps glioblastomas evade immune attack

Cancer-initiating cells that launch glioblastoma multiforme, the most lethal type of brain tumor, also suppress an immune system attack on the disease, scientists from The University of Texas M. D. Anderson Cancer Center report in a paper featured on the cover of the Jan. 15 issue of Clinical Cancer Research.

18 Jan 2010

Scripps Research scientists produce chemically complex compound

In 1993 researchers discovered a chemical compound in a sponge off Palau, an island nation in the Pacific Ocean, that has shown anticancer, antibacterial, and antifungal pharmaceutical promise. But that wasn't its greatest allure, at least not for chemists.

13 Jan 2010

Study: Patients with specific oncogenic rearrangements of ALK gene show greater response to new therapy

Results of a new study in non-small cell lung cancer showed that patients with specific oncogenic rearrangements of the anaplastic lymphoma kinase (ALK) gene within the short arm of chromosome 2 of their tumors had a much greater response to a new therapy - an ALK-inhibitor.

13 Jan 2010

Molecule News and Research

Patients Medical offers prevention tips for patients during heart health month

TUM biophysicists map changes in energy landscape of zipper-like protein molecule

Scientists study fruit fly to identify key molecular signal in cancer metastasis

HSF1A stimulates more protein chaperones and reduces protein misfolding

European Patent Office grants a patent for Rexahn Pharmaceuticals' RX-3117

Microbiologists explain why apples are beneficial for health

Novartis obtains exclusive worldwide rights to develop and commercialize Chiasma's TPE technology

PCI Biotech AS completes second dose group in phase I/II study of Amphinex

EMBL-EBI hosts drug discovery database

Boehringer Ingelheim, Priaxon announce collaboration in development of mdm2/p53 inhibitors for cancer

Babraham Institute research may lead to new means of making purified T cells

Need for further studies on clinical characteristics of Intrahepatic Cholangiocarcinoma

New findings reveal tendons play an active role in initiating bone ridge formation

Race against time to produce artificial blood substitute

Breakthrough discovery could lead to new treatments for a variety of CNS disorders

Researchers discover how cells flatten out as they adhere to internal bodily surfaces

Research reveals gene activation is linked to most aggressive type of brain cancer

M. D. Anderson researchers discover mechanism that helps glioblastomas evade immune attack

Scripps Research scientists produce chemically complex compound

Study: Patients with specific oncogenic rearrangements of ALK gene show greater response to new therapy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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