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Study details the key role played by neutrophils in ensuring survival of brain cancers

A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.

27 Sep 2023

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Small and precise: These are the ideal characteristics for CRISPR systems, the Nobel-prize winning technology used to edit nucleic acids like RNA and DNA.

27 Sep 2023

Gene-silencer study could pave the way for novel cancer therapeutics

Deep inside our cells-;each one complete with an identical set of genes-;a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

26 Sep 2023

SRI spins off a biosciences platform that accelerates drug discovery

SRI International announced today it is spinning off Synfini, a biosciences platform that accelerates the process by which pharmaceutical and other companies can design, synthesize, and bring to market molecules for drug development.

26 Sep 2023

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

Molnupiravir, an antiviral drug used to treat patients with COVID-19, appears to be driving SARS-CoV-2 to mutate and evolve, with some of these new viruses being transmitted onwards, a new study has shown. It is not clear, however, whether these mutated viruses pose an increased risk to patients or are able to evade the vaccine.

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

By means of CRISPR screening, LMU researchers have provided the first ever comprehensive molecular characterization of T cell infiltration into the central nervous system of people with MS.

22 Sep 2023

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Immunotherapy, which uses the body's own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it.

21 Sep 2023

Rice engineers develop split gene-editing tool with enhanced control

To make a gene-editing tool more precise and easier to control, Rice University engineers split it into two pieces that only come back together when a third small molecule is added.

21 Sep 2023

UQ researchers identify novel drug target to overcome cancer drug resistance

University of Queensland researchers have identified a novel drug target with the potential to overcome drug resistance and prevent tumor regrowth in cancer patients.

20 Sep 2023

Study identifies a molecule that may be behind COVID-19 brain fog

A study identifies a molecule that may be behind cognitive symptoms, including "brain fog," experienced by those infected by the SARS-CoV-2 virus.

20 Sep 2023

LabGenius & Sanofi partnership yields positive results from AI antibody discovery platform

Today, LabGenius, a pioneer in the use of AI and machine learning for antibody discovery, releases new data from its antibody discovery platform following a multi-year collaboration with Sanofi.

From LabGenius 19 Sep 2023

New treatment approach effectively treats the most aggressive forms of prostate cancer

Researchers at the University of Chicago Medicine Comprehensive Cancer Center established "proof-of-concept" for a new treatment approach that was able to effectively treat the most aggressive forms of prostate cancer. The treatment showed complete tumor control and long-lasting survival without side effects in a mouse model of advanced prostate cancer.

19 Sep 2023

New CAR T cell therapy approach minimizes severe side effects

In recent years, cancer researchers have hailed the arrival of chimeric antigen receptor T cell (CAR T) therapy, which has delivered promising results, transforming the fight against various forms of cancer. The process involves modifying patients' T-cells to target cancer cells, resulting in remarkable success rates for previously intractable forms of cancer.

19 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Study highlights a promising therapy to mitigate spaceflight-induced bone loss

A new study published in a Nature Partner Journal, npj Microgravity, finds an engineered compound given to mice aboard the International Space Station (ISS) largely prevented the bone loss associated with time spent in space.

18 Sep 2023

NO-ferroheme behaves as a signaling entity in the vasculature

Although a simple molecule, nitric oxide is an important signal substance that helps to reduce blood pressure by relaxing the blood vessels.

14 Sep 2023

Mesenchymal stem cell-derived extracellular vesicles show promise in PCOS treatment

Polycystic ovary syndrome (PCOS) is a pervasive endocrine disorder that affects millions of women globally, impacting their hormonal balance, fertility and overall well-being.

12 Sep 2023

New class of iron-targeting compounds found to hamper proliferation of cancer cells

Researchers at the University of Arizona Cancer Center discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting.

12 Sep 2023

“Inverse vaccine” shows promise to reverse autoimmune diseases without shutting down rest of the immune system

A new type of vaccine developed by researchers at the University of Chicago's Pritzker School of Molecular Engineering (PME) has shown in the lab setting that it can completely reverse autoimmune diseases like multiple sclerosis, type 1 diabetes, and Crohn's disease -; all without shutting down the rest of the immune system.

12 Sep 2023

Molecule News and Research

Study details the key role played by neutrophils in ensuring survival of brain cancers

Small and precise CRISPR-Cas13bt3 system can be used to shred viruses

Gene-silencer study could pave the way for novel cancer therapeutics

SRI spins off a biosciences platform that accelerates drug discovery

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Rice engineers develop split gene-editing tool with enhanced control

UQ researchers identify novel drug target to overcome cancer drug resistance

Study identifies a molecule that may be behind COVID-19 brain fog

LabGenius & Sanofi partnership yields positive results from AI antibody discovery platform

New treatment approach effectively treats the most aggressive forms of prostate cancer

New CAR T cell therapy approach minimizes severe side effects

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Study highlights a promising therapy to mitigate spaceflight-induced bone loss

NO-ferroheme behaves as a signaling entity in the vasculature

Mesenchymal stem cell-derived extracellular vesicles show promise in PCOS treatment

New class of iron-targeting compounds found to hamper proliferation of cancer cells

“Inverse vaccine” shows promise to reverse autoimmune diseases without shutting down rest of the immune system

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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