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New gene found in genetic wasteland

In a region of DNA long considered a genetic wasteland, Harvard Medical School researchers have discovered a new class of gene.

20 Jun 2004

A natural molecule that blocks a key bacterial enzymes could lead to a new generation of antibiotics

Rutgers scientists have deciphered the complex mechanics of microcin J25 (MccJ25), a tiny, natural molecule that acts like a cork in a bottle to block a key bacterial enzyme – potentially leading to a new generation of antibiotics.

17 Jun 2004

3dgenome program should lead to a breakthrough in our understanding of how our genome functions

Under the EU Sixth Framework Programme (FP6) for Research and Development (2002-2006) 2.2 million Euros have been awarded to the 3DGENOME-research program.

17 Jun 2004

Potential new strategy for blocking tumor growth

Targeting a master molecule that helps cancer cells survive when blood oxygen levels are low may offer a potentially powerful strategy for blocking tumor growth, say researchers at The University of Texas M. D. Anderson Cancer Center.

16 Jun 2004

New target to stop breast cancer growth

Two proteins that normally help cells move from place to place and are made in large quantities in breast cancer cells work together to promote the survival and spread of breast cancer, according to a new study by scientists at The University of Texas M. D. Anderson Cancer Center.

15 Jun 2004

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population. In a new study, scientists may have found a culprit: a serious deficiency of nitric oxide, a small molecule vital in the regulation of blood flow and blood pressure.

11 Jun 2004

Project aimed at eliminating anthrax as a potential weapon for terrorists

La Trobe University scientists are using their own unique peptide 'library' containing a thousand million molecular sequences in a project aimed at eliminating anthrax as a potential weapon for terrorists.

10 Jun 2004

Computational design used to engineer and construct a protein that could sense the nerve agent soman

Duke University Medical Center biochemists have used computational design to engineer and construct a protein that could sense the nerve agent soman. They said their achievement constitutes a proof-of principle that such engineered proteins can be made to detect nerve agents such as sarin and other toxic substances.

5 Jun 2004

Proteins transform DNA into molecular velcro

Proteins critical for compacting DNA in preparation for cell division actually interact with the double helix to fashion it into a kind of “molecular Velcro,” researchers have discovered.

5 Jun 2004

Drug Tarceva improves survival chance for patients with advanced lung cancer

Roche OSI Pharmaceuticals and Genentech today announced that their investigational drug Tarceva(TM) (erlotinib) achieved a significant 42.5% improvement in median survival compared to placebo in patients with advanced non-small cell lung cancer (NSCLC).

5 Jun 2004

Fibroid tumors lack crucial structural protein

Fibroid tumors-the sometimes painful uterine growths affecting many American women-lack a key protein that plays a role in holding tissues together, according to a study by researchers from the Uniformed Services University of the Health Sciences (USUHS) and the National Institute of Child Health and Human Development of the National Institutes of Health

3 Jun 2004

Scientists reveal the crystal structure of the first described enzymatic RNA

Scientists in the department of molecular biophysics and biochemistry at Yale revealed the crystal structure of the first described enzymatic RNA - what it looks like and how it reacts - in the journal Nature.

2 Jun 2004

Fibroid tumors affecting many American women lack a key protein helps hold tissues together

Fibroid tumors — the sometimes painful uterine growths affecting many American women — lack a key protein that plays a role in holding tissues together, according to a study by researchers from the Uniformed Services University of the Health Sciences (USUHS) and the National Institute of Child Health and Human Development of the National Institutes of Health.

2 Jun 2004

Understanding focal adhesion kinase (FAK) may lead to new cancer treatments

Scientists at the University of North Carolina at Chapel Hill have found an unexpected way to turn off a cellular enzyme involved in the progression of several types of human cancers.

2 Jun 2004

Genes that allow nerve cells to communicate may have come from bacteria eons ago

Some of the genes that allow nerve cells and some other types of cells to send elaborate chemical messages to each other appear to have been transferred to animals or their immediate ancestors from bacteria eons ago.

2 Jun 2004

Students win awards for research into liver disease, cancer and insomnia

Targeting a range of diseases and disorders, three University of Houston students won awards at a recent symposium for research in liver disease, cancer and insomnia.

2 Jun 2004

New therapy to send cancer-killing drugs directly to tumours

Disguising a molecule to get it past the body's immune system could greatly enhance the success of a groundbreaking new therapy, Cancer Research UK scientists report in the British Journal of Cancer this week.

2 Jun 2004

Novel molecular targeting technologies to deliver gene-silencing therapy

Researchers have combined novel molecular targeting technologies to deliver gene-silencing therapy specifically to tumor cells shielded by a normally impermeable obstacle, the blood brain barrier.

1 Jun 2004

Four critical components of cells' protein-building machine don't do what scientists had long assumed

In the hunt for these details, scientists have focused on four RNA building blocks, or nucleotides, deep within the machine that are identical in every species, from bacteria to humans. Because they sit where the protein chain is actually built, these "universally conserved" nucleotides in the ribosome were thought to help that process.

28 May 2004

Researchers identify molecules that underlie nerve fiber degeneration in multiple sclerosis patients

Yale researchers and collaborators have identified molecules that underlie nerve fiber degeneration in patients with secondary progressive multiple sclerosis (MS), a disease that cripples nearly three million people worldwide. The new findings are the first observations in humans of molecules that contribute to degeneration of nerve fibers.

27 May 2004

Molecule News and Research

New gene found in genetic wasteland

A natural molecule that blocks a key bacterial enzymes could lead to a new generation of antibiotics

3dgenome program should lead to a breakthrough in our understanding of how our genome functions

Potential new strategy for blocking tumor growth

New target to stop breast cancer growth

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population

Project aimed at eliminating anthrax as a potential weapon for terrorists

Computational design used to engineer and construct a protein that could sense the nerve agent soman

Proteins transform DNA into molecular velcro

Drug Tarceva improves survival chance for patients with advanced lung cancer

Fibroid tumors lack crucial structural protein

Scientists reveal the crystal structure of the first described enzymatic RNA

Fibroid tumors affecting many American women lack a key protein helps hold tissues together

Understanding focal adhesion kinase (FAK) may lead to new cancer treatments

Genes that allow nerve cells to communicate may have come from bacteria eons ago

Students win awards for research into liver disease, cancer and insomnia

New therapy to send cancer-killing drugs directly to tumours

Novel molecular targeting technologies to deliver gene-silencing therapy

Four critical components of cells' protein-building machine don't do what scientists had long assumed

Researchers identify molecules that underlie nerve fiber degeneration in multiple sclerosis patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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