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Paxlovid enhances treatment options for COVID-19 patients

The design, synthesis, and mechanism of action of Paxlovid.

6 Feb 2024

Researchers identify the basic principles of serotonin transport in nerve cells

Drugs known as antidepressants target the serotonin transporter in nerve cells and are among the most commonly prescribed medicines worldwide, but are sometimes associated with significant side effects.

5 Feb 2024

New research facility at the University of Surrey could soon unlock the secrets of diseases

A new research facility at the University of Surrey could soon help society better understand various diseases or even help scientists trace nanoplastics through the bodies and cells of humans and animals.

5 Feb 2024

New approach to treating neuropathic pain offers the possibility of non-opioid pain relief for millions

Researchers investigated the selective activity of sigmoid 2 receptor (σ2R) or transmembrane protein 97 (TMEM97) ligands on murine neuropathic pain models, their effects on nociceptive neurons and the mechanism of action after 24 hours.

5 Feb 2024

SCIEX expands high-throughput screening solutions with Echoâ MS+ system

The Echo® MS+ system unlocks enhanced high-throughput screening capability by bringing acoustic ejection mass spectrometry (AEMS) approaches to the SCIEX ZenoTOF 7600 system.

From SCIEX 5 Feb 2024

Tecan offers end-to-end solutions for cellomics: automated workflows from single-cell dispensing to 3D spheroid analysis

Tecan is proud to offer end-to-end cellomics workflow solutions, including cell seeding and culture with quality control and monitoring, through drug dosing to live-cell imaging and analysis. This comprehensive offering enables laboratories to improve the reliability, reproducibility and throughput of their workflows, addressing key challenges in the growing field of 3D cell biology.

5 Feb 2024

Small-molecule A485 mobilizes white blood cells on demand

New study reveals a small molecule that can selectively mobilize white blood cells, offering potential treatments for diseases with abnormal leukocyte counts.

3 Feb 2024

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the "living drugs" can be harnessed against other diseases, like autoimmune disorders.

2 Feb 2024

New molecule is one step closer to becoming a treatment for Phelan-McDermid syndrome

A molecule created at the University of Auckland is one step closer to becoming a treatment for an extremely rare and severely debilitating neurological disorder called Phelan-McDermid syndrome.

2 Feb 2024

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations has identified a next-generation BTK degrader that could help overcome treatment resistance in chronic lymphocytic leukemia (CLL) and related blood cancers.

1 Feb 2024

Specific epigenetic pathway found to be involved in the development of melanoma drug resistance

One of the major challenges in cancer research and clinical care is understanding the molecular basis for therapeutic resistance as a major cause of long term treatment failures.

1 Feb 2024

X-chromosome inactivation and its role in autoimmune susceptibility in females

Somewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our own tissues. As many as 4 out of 5 of those people are women.

1 Feb 2024

Scientists uncover a way to "hack" neurons' internal clocks to speed up brain cell development

The neurons that make up our brains and nervous systems mature slowly over many months.

31 Jan 2024

Researchers discover non-opioid therapeutic for relieving neuropathic pain

Among the most difficult types of pain to alleviate is neuropathic pain, pain that is usually caused by damage to nerves in various body tissues, including skin, muscle and joints.

31 Jan 2024

Ancient genomes unearth degenerate transposable elements in human DNA

The human genome, an intricate tapestry of genetic information for life, has proven to be a treasure trove of strange features. Among them are segments of DNA that can "jump around" and move within the genome, known as "transposable elements" (TEs).

30 Jan 2024

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

There are many lingering mysteries from the COVID-19 pandemic. For instance, why does SARS-CoV-2, the virus behind the disease, cause severe symptoms in some patients, while many other coronaviruses don't? And what causes strange symptoms to persist even after the infection has been cleared from a person's system?

30 Jan 2024

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells.

30 Jan 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Bio-Techne Corporation (NASDAQ: TECH) today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

Study sheds new light on how obesity affects fat cells' mitochondria

The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities.

29 Jan 2024

How does the nasal cavity's immune system combat SARS-CoV-2?

Researchers discovered that CD4+ and CD8+ T cells play a crucial role in clearing COVID-19 infection in the nasal cavity but have limited impact on lung infections, with implications for understanding and treating the virus.

28 Jan 2024

Molecule News and Research

Paxlovid enhances treatment options for COVID-19 patients

Researchers identify the basic principles of serotonin transport in nerve cells

New research facility at the University of Surrey could soon unlock the secrets of diseases

New approach to treating neuropathic pain offers the possibility of non-opioid pain relief for millions

SCIEX expands high-throughput screening solutions with Echoâ MS+ system

Tecan offers end-to-end solutions for cellomics: automated workflows from single-cell dispensing to 3D spheroid analysis

Small-molecule A485 mobilizes white blood cells on demand

CAR T cells target senescent cells, improve healthspan in mice

New molecule is one step closer to becoming a treatment for Phelan-McDermid syndrome

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

Specific epigenetic pathway found to be involved in the development of melanoma drug resistance

X-chromosome inactivation and its role in autoimmune susceptibility in females

Scientists uncover a way to "hack" neurons' internal clocks to speed up brain cell development

Researchers discover non-opioid therapeutic for relieving neuropathic pain

Ancient genomes unearth degenerate transposable elements in human DNA

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

Improving mitochondrial metabolism could be a potential therapeutic target for Alzheimer's

Bio-Techne’s Advanced Cell Diagnostics (ACD) sets new standard in spatial biology with protease-free RNAscope multiomics

Study sheds new light on how obesity affects fat cells' mitochondria

How does the nasal cavity's immune system combat SARS-CoV-2?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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