Monoclonal Antibody News and Research

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Monoclonal antibodies (MAbs) are produced from a single B cell clone and can bind to a single type of antigen binding site. MAbs are homogenous antibodies that cannot form lattices with monomeric proteins as they can bind to only a single epitope on the antigen. Developed in the 1970s, MAbs can be produced against any given substance. Thus they can be used to detect and purify any substance of interest. This has made MAbs a powerful tool of molecular biology, biochemistry, and medicine.
The efficacy of therapeutic monoclonal antibodies and serum from monoclonal antibody-treated patients against Omicron sublineages

The efficacy of therapeutic monoclonal antibodies and serum from monoclonal antibody-treated patients against Omicron sublineages

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

Antibody evasion of Omicron BA.2.75 is less pronounced than BA.4/5

Antibody evasion of Omicron BA.2.75 is less pronounced than BA.4/5

Next-generation monoclonal antibody prevents malaria

Next-generation monoclonal antibody prevents malaria

Trial evaluates sugemalimab as a consolidation treatment in patients with unresectable stage III NSCLC

Trial evaluates sugemalimab as a consolidation treatment in patients with unresectable stage III NSCLC

Researchers identify mechanistic principles for engineering antibodies to enhance cadherin adhesion

Researchers identify mechanistic principles for engineering antibodies to enhance cadherin adhesion

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Novel fusion protein drug for Alzheimer’s disease circumvents the neurotoxic inflammatory side effects

Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

Monoclonal antibody protects U.S. adults from malaria, Phase 1 clinical trial shows

What are the hidden sources of SARS-CoV-2 evolution?

What are the hidden sources of SARS-CoV-2 evolution?

How and when do de novo SARS-CoV-2 spike mutations emerge?

How and when do de novo SARS-CoV-2 spike mutations emerge?

The identification and characterization of an anti-SARS-CoV-2 monoclonal antibody with superior breadth and potency

The identification and characterization of an anti-SARS-CoV-2 monoclonal antibody with superior breadth and potency

Everything you need to know about Paxlovid — especially, should you take it?

Everything you need to know about Paxlovid — especially, should you take it?

Study shows the emerging Omicron sublineage BA.2.75 does not show greater immune evasion than BA.5

Study shows the emerging Omicron sublineage BA.2.75 does not show greater immune evasion than BA.5

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

Researchers develop a rapid, specific, and accurate RT-qPCR-based method to detect and distinguish between Omicron sublineages

Researchers develop a rapid, specific, and accurate RT-qPCR-based method to detect and distinguish between Omicron sublineages

UC San Francisco neurologists focus on the hazards of abortion restrictions for women of reproductive age

UC San Francisco neurologists focus on the hazards of abortion restrictions for women of reproductive age