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Enrollment complete in REPRISE I clinical trial for Lotus Aortic Valve System

Boston Scientific Corporation announces that it has completed enrollment in the REPRISE I clinical trial, which is designed to evaluate the acute safety of the Lotus Aortic Valve System, the first transcatheter aortic valve replacement (TAVR) device of its kind for patients with severe aortic valve stenosis that is both fully repositionable and retrievable prior to release.

23 Apr 2012

Measles report card for 2011 shows too many cases

According to the CDC in its Morbidity and Mortality Weekly Report, last year was the worst year for measles in the U.S. in 15 years. They report that there were 222 cases of measles, a large jump from the 60 or so seen in a typical year. Most of the cases last year were imported — either by foreign visitors or by U.S. residents who picked up the virus overseas.

22 Apr 2012

Women with ACS receive inferior or less aggressive treatment compared to men

Women with acute coronary syndrome (ACS) receive inferior or less aggressive treatment compared to men, according to three large studies presented today at the World Congress of Cardiology.

21 Apr 2012

Two salt reduction strategies could decrease CVD mortality

Voluntary industry reductions in salt content and taxation on products containing salt in 19 developing countries could reduce the number of deaths each year from cardiovascular disease (CVD) by 2-3 per cent in these countries.

21 Apr 2012

Orthopaedic research studies in the Journal of Bone and Joint Surgery

Below are highlights of orthopaedic research studies appearing in the April 18th issue of the Journal of Bone and Joint Surgery (JBJS), as well as the issue's full Table of Contents.

21 Apr 2012

Research roundup: Caring for dual eligibles; Antitrust policy and the health law

Using data from the Centers for Disease Control and Prevention (CDC), this report notes a systematic difference in life expectancy across region and race. "Within in each sex-race group, there are striking geographical differences in the probability of survival to age 70. ... These differences are larger for males than females within each race and larger for blacks than whites within each sex."

21 Apr 2012

Two new studies analyze treatment decisions in late-stage ALS patients

Two new studies analyzing treatment decisions in late-stage amyotrophic lateral sclerosis (ALS) patients shed light onto treatments aimed to extend the duration and quality of life in this progressively debilitating neuromuscular disorder.

21 Apr 2012

Exercise may help smokers to quit, reduce risk of CVD

Exercise may help smokers to quit and remain smokefree, according to new data presented today at the World Congress of Cardiology. Moreover, exercise increases life expectancy in smokers and non-smokers alike.

21 Apr 2012

Positive results from Alnylam’s ALN-PCS Phase I trial on severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive results from its Phase I clinical trial of ALN-PCS, an RNAi therapeutic targeting PCSK9 for the treatment of severe hypercholesterolemia.

21 Apr 2012

Therapeutic hypothermia reduces in-hospital deaths among sudden cardiac arrest patients

Forced body cooling known as therapeutic hypothermia has reduced in-hospital deaths among sudden cardiac arrest patients nearly 12 percent between 2001 and 2009, according to a Mayo Clinic study being presented at the upcoming American Academy of Neurology 2012 Annual Meeting in New Orleans.

20 Apr 2012

Researchers identify risks in pregnancy related specifically to obesity

Obese women run the risk of problems during pregnancy, labour and complications for the baby's health. A new study of more than 3000 expectant mothers confirms this, and also reveals that being underweight also has specific complications.

20 Apr 2012

ESC launches European Heart Journal: Acute Cardiovascular Care

The European Society of Cardiology (ESC) announced today the launch of the European Heart Journal: Acute Cardiovascular Care, the organisation's official journal of the ESC Working Group on Acute Cardiac Care.

20 Apr 2012

ACS report outlines gaps and opportunities that contribute to cancer mortality

An annual report from the American Cancer Society says much of the suffering and death from cancer could be prevented by more systematic efforts to reduce tobacco use, improve diet and physical activity, reduce obesity, and expand the use of established screening tests. The report, Cancer Prevention and Early Detection Facts and Figures (CPED), outlines gaps and opportunities that contribute to cancer mortality, and says social, economic, and legislative factors profoundly influence individual health behaviors.

20 Apr 2012

Thinking about death can actually be a good thing

Thinking about death can actually be a good thing. An awareness of mortality can improve physical health and help us re-prioritize our goals and values, according to a new analysis of recent scientific studies. Even non-conscious thinking about death - say walking by a cemetery - could prompt positive changes and promote helping others.

20 Apr 2012

Physical activity reduces CVD mortality risk in patients with hypertension

In the study, all-cause and CVD mortality risks were found to be significantly higher among study participants that didn't exercise compared with active participants at all blood pressure levels. Moreover, the excess mortality risks of physical inactivity, when converted into a "blood pressure equivalence of physical activity" measurement, revealed that physical inactivity was similar to a rise in mortality risk equivalent to an increase in blood pressure of 40-50 mmHg.

20 Apr 2012

Two studies show true impact of liver disease across Europe

Two studies presented at the International Liver Congress- 2012 show the true impact that liver disease has across Europe. One highlights the financial cost of liver disease to the community and the second highlights the high mortality rates associated with cirrhosis.

19 Apr 2012

UCSD named among 100 Top Hospitals by Thomson Reuters

UC San Diego Medical Center, located in Hillcrest, has been named one of the nation's 100 Top Hospitals by Thomson Reuters. Ranked among the country's major teaching hospitals, the Medical Center was also one of twelve hospitals to receive the Everest Award. This award honors hospitals that have achieved both the highest current performance and the fastest long-term improvement over a five-year period in Reuter's national benchmarking study.

19 Apr 2012

First specific antidote for cocaine toxicity

Scientists at The Scripps Research Institute have shown that an injectable solution can protect mice from an otherwise lethal overdose of cocaine. The findings could lead to human clinical trials of a treatment designed to reverse the effects of cocaine in case of emergency. Cocaine is involved in more than 400,000 emergency-room visits and about 5,000 overdose deaths each year in the United States.

19 Apr 2012

Autologous BMMNCs reduce vascular growth in patients with diabetes

Autologous (self-donated) mononuclear cells derived from bone marrow (BMMNCs) have been found to significantly induce vascular growth when transplanted into patients with diabetes who are suffering from critical limb ischemia caused by peripheral artery disease (PAD), a complication of diabetes.

19 Apr 2012

Trauma patients flown in to the A&E may fare better: Study

A new study has found that transport by helicopter to a level I or II trauma center was associated with improved survival to hospital discharge compared with ground emergency medical services. The study, which appears in the April 18 issue of JAMA, included data on more than 200,000 adult patients.

18 Apr 2012