Motor Neuron Disease News and Research

RSS

Same genetic defects shared by some patients with motor neuron disease and frontotemporal dementia

New research has discovered that some patients with motor neuron disease (MND) and frontotemporal dementia (FTD) carry the same rare genetic defects that cause other neurodegenerative diseases.

9 May 2023

UQ research could lead to viable treatments for motor neuron disease

Research at The University of Queensland could eventually help develop viable treatments - and ultimately a cure - for motor neuron disease (MND).

26 Apr 2023

Discovery suggests a new way to treat spinal muscular atrophy

Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy (SMA), a critical piece of information about the disease that neurologists have been seeking for decades.

23 Mar 2023

Innate immune molecule could be at the root of ALS

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures.

13 Mar 2023

Using artificial intelligence methods to predict the prevalence of ALS

Amyotrophic lateral sclerosis (ALS)—a severe disease of the motor nervous system—is hereditary, but a large part of this heritability has previously been unexplained.

28 Feb 2023

Clinical suite to help unlock the mysteries of neurological disorders

A clinical suite at a University of Queensland health research facility is ready to help unlock the mysteries of neurological conditions experienced by one billion people worldwide.

26 Sep 2022

Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

DZNE and Intravacc receive € 2.5 million EU funding to develop a prototype ALS vaccine

DZNE and Intravacc B.V., a world leading contract development and manufacturing organization (CDMO) of preventive and therapeutic vaccines, have been awarded a funding of € 2.5 million from the European Union (EIC Transition Grant) to further develop a prototype ALS vaccine, including process development, scale-up, and toxicology study.

6 Jul 2022

£4.25 million research grant seeks to discover meaningful treatments for motor neuron disease

A group of charities and government research organisations has awarded £4.25 million to MND experts at six UK universities to kick start collaborative efforts to end motor neuron disease (MND).

20 Jun 2022

New DNA test can quickly and accurately identify a range of hard-to-diagnose genetic diseases

A new DNA test, developed by researchers at the Garvan Institute of Medical Research in Sydney and collaborators from Australia, UK and Israel, has been shown to identify a range of hard-to-diagnose neurological and neuromuscular genetic diseases quicker and more-accurately than existing tests.

4 Mar 2022

€10 million ‘precision medicine’ research project launched to provide new insights into ALS

An ambitious academic, clinical and industry research programme that will provide new insights into our understanding of Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS), was launched today by Tánaiste and Irish Minister for Enterprise, Trade and Employment, Leo Varadkar T.D.

1 Mar 2022

First platform trial for ALS hopes to accelerate the development of effective treatments

A new paper in Annals of Neurology describes the approach, structure, and launch of the HEALEY ALS Platform Trial– the first platform trial for amyotrophic lateral sclerosis (ALS) designed to accelerate the development of effective and breakthrough treatments for people with the illness.

28 Feb 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Winners of the first CERF Medical Engineering Prize for ALS Research announced

The Cullen Education and Research Fund announced the recipients of the first CERF Medical Engineering Prize for ALS Research: Dr. Leigh Hochberg, Dr. Conor Walsh, and Dr. Sabrina Paganoni.

8 Feb 2022

Blood tests may enable simpler, more accurate early diagnosis of ALS

Blood tests may enable more accurate diagnosis of ALS at an earlier stage of the disease. As described in a study by researchers at University of Gothenburg and Umeå University, it involves measuring the blood level of a substance that, as they have also shown, varies in concentration depending on which variant of ALS the patient has.

28 Jan 2022

Motor Neuron Disease News and Research

Same genetic defects shared by some patients with motor neuron disease and frontotemporal dementia

UQ research could lead to viable treatments for motor neuron disease

Discovery suggests a new way to treat spinal muscular atrophy

Innate immune molecule could be at the root of ALS

Using artificial intelligence methods to predict the prevalence of ALS

Clinical suite to help unlock the mysteries of neurological disorders

Repurposed drug shows promise as potential new treatment for motor neuron disease

DZNE and Intravacc receive € 2.5 million EU funding to develop a prototype ALS vaccine

£4.25 million research grant seeks to discover meaningful treatments for motor neuron disease

New DNA test can quickly and accurately identify a range of hard-to-diagnose genetic diseases

€10 million ‘precision medicine’ research project launched to provide new insights into ALS

First platform trial for ALS hopes to accelerate the development of effective treatments

Novel molecular pathway shared by two neurodegenerative disorders discovered

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Winners of the first CERF Medical Engineering Prize for ALS Research announced

Blood tests may enable simpler, more accurate early diagnosis of ALS

Scientists reveal toxic astrocyte changes in ALS

Novel biomarker can be used to identify disease progression in ALS

Scientists determine structure of the molecule associated with ALS for the first time

Targeting the brain should be the focus of ALS therapy, not just spinal cord

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Latest News