Mouse Model News and Research

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Novel chronic murine wound mouse model to study cellular senescence

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "A chronic wound model to investigate skin cellular senescence."

2 May 2023

Inhibiting mitochondrial regulator ATAD3A could prevent head and neck cancer development

A new research perspective was published in Oncoscience (Volume 10) on April 4, 2023, entitled, "Mitochondrial regulator ATAD3A: a molecular determinant favoring head and neck cancer development."

28 Apr 2023

Scientists identify broad-spectrum antiviral agents that can target multiple RNA virus families

A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.

28 Apr 2023

Research identifies Th1 memory CD4+ T cells as key to protect against emerging poxvirus skin infections

Researchers demonstrate that T helper 1 effector memory cluster of differentiation 4 T cells provide immunity against poxviruses

27 Apr 2023

Research uncovers antibodies that are still effective against new variants of SARS-CoV-2

An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

26 Apr 2023

Researchers take key step toward developing a gene therapy for Usher syndrome type 1F

Usher Syndrome type 1F is a rare but severe genetic disease that causes deafness, lack of balance, and progressive blindness.

26 Apr 2023

Researchers shed light on the genetics behind facial changes in Down syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

26 Apr 2023

Neutrophils found to play a key role in fibromyalgia pain

Targeting neutrophil activity and interactions with sensory neurons may be a potential approach for treating fibromyalgia pain.

25 Apr 2023

Researchers discover a receptor and protein associated with Lou Gehrig's disease

Researchers at Nagoya University in Japan have discovered a receptor, sigma-1 receptor, and a protein, ATAD3A, that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease.

25 Apr 2023

Researchers uncover the molecular basis for making long-term memories

Helping your mother make pancakes when you were three…riding your bike without training wheels…your first romantic kiss: How do we retain vivid memories of long-ago events? As described in a paper published online on April 25 in Neuron, researchers at Albert Einstein College of Medicine have found the explanation.

25 Apr 2023

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

24 Apr 2023

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

A discovery about gene variants of an inflammation 'brake' brings scientists a step closer to personalised treatment for patients at risk of kidney disease and kidney failure.

24 Apr 2023

Researchers discover a key player in preventing 'insulin shock'

Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for type 2 diabetes, as well.

24 Apr 2023

Study finds sex differences in the healing process after a muscle injury

The time period in which muscles heal after injury may depend on biological sex, and applying personalized treatment may help optimize recovery, according to a new study.

21 Apr 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

Researchers identify a type of immune cell that drives chronic organ transplant failure

University of Pittsburgh researchers have identified a type of immune cell that drives chronic organ transplant failure in a mouse model of kidney transplantation and uncovered pathways that could be therapeutically targeted to improve patient outcomes.

21 Apr 2023

Binocular visual stimulation followed by sleep helps treat common vision problem in children

Amblyopia, sometimes called lazy eye, is a common vision problem in children and babies, and it’s typically been treated by having the child wear a patch on the stronger eye, with the goal of improving sight for the weaker eye.

18 Apr 2023

Discovery could be the key to unlocking new, more successful treatments for glioblastoma

For decades, researchers have marveled at the ability of glioblastoma, a particularly aggressive brain cancer, to turn off a patient's cancer-fighting immune cells, thereby allowing tumors to grow freely.

18 Apr 2023

Tissue-resident memory cells are key to immunity to Salmonella in mice

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

New discovery can revolutionize the diagnosis and treatment of Alzheimer's disease

Recently, a team of South Korean scientists led by Director C. Justin LEE of the Center for Cognition and Sociality within the Institute for Basic Science made a new discovery that can revolutionize both the diagnosis and treatment of Alzheimer's Disease.

17 Apr 2023

Mouse Model News and Research

Novel chronic murine wound mouse model to study cellular senescence

Inhibiting mitochondrial regulator ATAD3A could prevent head and neck cancer development

Scientists identify broad-spectrum antiviral agents that can target multiple RNA virus families

Research identifies Th1 memory CD4+ T cells as key to protect against emerging poxvirus skin infections

Research uncovers antibodies that are still effective against new variants of SARS-CoV-2

Researchers take key step toward developing a gene therapy for Usher syndrome type 1F

Researchers shed light on the genetics behind facial changes in Down syndrome

Neutrophils found to play a key role in fibromyalgia pain

Researchers discover a receptor and protein associated with Lou Gehrig's disease

Researchers uncover the molecular basis for making long-term memories

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

Researchers discover a key player in preventing 'insulin shock'

Study finds sex differences in the healing process after a muscle injury

Researchers develop a backpack-based myeloid cell therapy for MS patients

Researchers identify a type of immune cell that drives chronic organ transplant failure

Binocular visual stimulation followed by sleep helps treat common vision problem in children

Discovery could be the key to unlocking new, more successful treatments for glioblastoma

Tissue-resident memory cells are key to immunity to Salmonella in mice

New discovery can revolutionize the diagnosis and treatment of Alzheimer's disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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