Muscle News and Research

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Muscle stem cells morph to resemble nerve cells

Taking a major step forward in stem cell biology, researchers at The University of Texas M. D. Anderson Cancer Center have turned muscle progenitor cells — stem cells that are “committed” to becoming muscle tissue — into cells that look and act like neurons (nerve cells).

14 Apr 2004

Ultrasound therapy does nothing to help an injured skeletal muscle heal any faster

Although ultrasound is one of the most frequently prescribed treatments for one of the most common sport and athletic injuries – skeletal muscle contusions – there's really no good scientific evidence showing that it treats injured muscles effectively, said Steven Devor, the study's lead author and an assistant professor of sport and exercise sciences at Ohio State University.

14 Apr 2004

Small uterine fibroids are associated with an increased risk of miscarriage

Early results from a pioneering study at the University of North Carolina at Chapel Hill indicate that small uterine fibroids are associated with an increased risk of miscarriage.

13 Apr 2004

Both sides of brain working together are key to math giftedness

There really may be something different about the brains of math-heads. Mathematically gifted teens did better than average-ability teens and college students on tests that required the two halves of the brain to cooperate, as reported in the April issue of Neuropsychology, published by the American Psychological Association (APA).

12 Apr 2004

Researchers pinpoint pathway to muscle regeneration

A team including MDA grantee Gordon Lynch in the Department of Physiology at the University of Melbourne in Victoria, Australia, found that a biological signaling pathway may help explain why mice with Duchenne muscular dystrophy (DMD) can regenerate their muscles much better than can humans with the same disease.

12 Apr 2004

Unique heart arrhythmia drug represents one of the first molecular-based therapies for heart failure

Heart researchers at Columbia University Medical Center have developed and tested a unique heart arrhythmia drug that could prevent the sudden death of millions of people with heart failure as well as people with an inherited heart disorder. The drug represents one of the first molecular-based therapies for heart failure and avoids the toxicity of current treatments.

8 Apr 2004

University of Florida researchers have used a common gel to successfully deliver gene therapy to the diaphragm

The technique, described in the current issue of Molecular Therapy, could eventually lead to a method to correct genetic conditions in humans that cause diaphragm weakness and respiratory failure -- a leading cause of death in tens of thousands of patients with forms of muscular dystrophy, including Pompe’s disease. Thousands of Americans with muscle-weakening diseases are placed on ventilators each year, according to the Muscular Dystrophy Association.

7 Apr 2004

Alcohol screening can spot addiction

Have you ever felt like you needed a drink? If an occasional cocktail changes into a need, it could mean an alcohol problem. National Alcohol Screening Day is April 8. In cities and towns throughout the United States, screening programs will be offered to help people determine whether they exhibit drinking behaviors that could be signs of alcohol addiction.

7 Apr 2004

Research shows that intense high dose cholesterol lowering drugs result in a major reduction in deaths and severe heart attacks

If you want to increase your chances of living longer, taking cholesterol drugs is an easy way to do it. That's the message from a Harvard study of 4,162 people hospitalized in 350 places in eight countries. It is the first research to show that intense lowering of cholesterol results in a major reduction in deaths and severe heart attacks.

7 Apr 2004

New study could lead to new drugs to prevent premature birth

Dr Raheela Khan, of the University’s Academic Division of Obstetrics and Gynaecology based at the newly-opened University of Nottingham Medical School at Derby, is working with colleagues Dr Balwir Matharoo-Ball and Dr Dave Barratt in the University’s School of Pharmacy on the research looking at what makes some women go into labour before their baby is due.

6 Apr 2004

Fluorescent molecule used to examine real time chemical reactions that result in smooth-muscle contraction

Smooth muscle, found in the walls of blood vessels and in internal organs such as lungs, stomach and the bladder, contracts as the end result of a series of chemical reactions. In a new study, UT Southwestern researchers report that one set of chemical reactions resulting in the contraction of the smooth-muscle cells is augmented by a second chemical pathway that kicks in when the first pathway is limited.

5 Apr 2004

Implantable defibrillator cuts heart attack risk of sudden death by 31%

Researchers at Loyola University Health System, Maywood, Ill., and the University of Rochester Medical Center, Rochester, N.Y., found that the previously demonstrated survival benefit of ICDs following a heart attack can last up to 15 years.

5 Apr 2004

First Approval in Europe of Ezetimibe/Simvastatin for treatment of elevated cholesterol

Merck/Schering-Plough Pharmaceuticals today announced the regulatory approval of INEGYTM (ezetimibe/simvastatin) in Germany for the treatment of elevated cholesterol (hypercholesterolemia). INEGY is the first product to reduce low-density lipoprotein cholesterol (LDL-C or ‘bad’ cholesterol), along with diet and exercise, through dual inhibition by inhibiting cholesterol production in the liver and absorption in the intestine. The approval of INEGY in Germany represents the first approval in Europe for ezetimibe/simvastatin tablets and the first step in seeking marketing approval throughout the European Union (EU) under the EU’s mutual recognition procedure.

4 Apr 2004

Study Looks at Risk Factors for Range-of-Motion Limitations In Young Males with Hemophilia

A paper in the April issue of Blood detailed research on the prevalence and risk factors joint range of motion (ROM) limitation among young males with hemophilia.

4 Apr 2004

New treatment for Tourette Syndrome, patients experience significant resolution of symptoms following brain surgery

A neurosurgical team at University Hospitals of Cleveland (UHC) has, for the first time in North America, applied a new surgical approach to the treatment of Tourette syndrome, resulting in the immediate and nearly complete resolution of symptoms for the patient, who has suffered from this neurologic disorder since he was a child.

1 Apr 2004

FDA has approved Zyprexa, injectable anti-psychotic drug

Physicians have a new fast-acting option for controlling the potentially crippling effects of acute agitation in patients suffering with schizophrenia and bipolar mania. The U.S. Food and Drug Administration (FDA) has approved Zyprexa® IntraMuscular (olanzapine for injection), an injectable form of Lilly's top-selling medication.

30 Mar 2004

£1.6m for research into a possible cure for muscular dystrophy

A consortium which includes Oxford researchers has won £1.6m in government funding for ground-breaking research into a possible cure for muscular dystrophy.

30 Mar 2004

£35m needed to boost M.E./Chronic Fatigue Syndrome research

National charity Action for M.E. is asking the government for £35 million to find a cure for M.E. - also known as Chronic Fatigue Syndrome. With government plans to boost medical research funding to £1.2bn per year M.E. research must be considered a priority area of investment.

27 Mar 2004

Texan child receives world's first scaled-down heart pump or child ventricular assist device

A six-year-old Texas Children's Hospital patient is the first pediatric patient in the world to receive a MicroMed/DeBakey® child ventricular assist device (VAD), recently approved by the FDA for use in children. The new, scaled-down heart pump improves blood flow for patients awaiting heart transplants.

27 Mar 2004

A common antibiotic used to treat arthritis and acne shows promise for limiting the severity of spinal cord and brain injuries

When a fall, car crash, bullet, or knife crushes or cuts a spinal cord, the injury does not stop there. Rather, tissues continue to discharge toxic chemicals for hours, even days and weeks. These chemicals kill and disable nerve cells some distance away from the core injury, compounding the damage and making rehabilitation more difficult or impossible.

26 Mar 2004

Muscle News and Research

Muscle stem cells morph to resemble nerve cells

Ultrasound therapy does nothing to help an injured skeletal muscle heal any faster

Small uterine fibroids are associated with an increased risk of miscarriage

Both sides of brain working together are key to math giftedness

Researchers pinpoint pathway to muscle regeneration

Unique heart arrhythmia drug represents one of the first molecular-based therapies for heart failure

University of Florida researchers have used a common gel to successfully deliver gene therapy to the diaphragm

Alcohol screening can spot addiction

Research shows that intense high dose cholesterol lowering drugs result in a major reduction in deaths and severe heart attacks

New study could lead to new drugs to prevent premature birth

Fluorescent molecule used to examine real time chemical reactions that result in smooth-muscle contraction

Implantable defibrillator cuts heart attack risk of sudden death by 31%

First Approval in Europe of Ezetimibe/Simvastatin for treatment of elevated cholesterol

Study Looks at Risk Factors for Range-of-Motion Limitations In Young Males with Hemophilia

New treatment for Tourette Syndrome, patients experience significant resolution of symptoms following brain surgery

FDA has approved Zyprexa, injectable anti-psychotic drug

£1.6m for research into a possible cure for muscular dystrophy

£35m needed to boost M.E./Chronic Fatigue Syndrome research

Texan child receives world's first scaled-down heart pump or child ventricular assist device

A common antibiotic used to treat arthritis and acne shows promise for limiting the severity of spinal cord and brain injuries

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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