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Propofol shows potential for treating epilepsy and neurological disorders

The general anesthetic propofol may hold the keys to developing new treatment strategies for epilepsy and other neurological disorders, according to a study led by researchers at Weill Cornell Medicine and Linköping University in Sweden.

31 Jul 2024

Weight loss guaranteed! But what impact on your diet? A review of GLP-1 and GIP/GLP-1 interventions

Researchers reviewed studies on dietary impacts of GLP-1 and GIP/GLP-1 receptor agonists in obesity and T2D patients, finding significant caloric reduction but limited evaluation of dietary composition.

29 Jul 2024

DNA repair gene mutations predict bladder cancer response to neoadjuvant chemotherapy

An analysis of pre-treatment tumor specimens from 105 patients with localized muscle-invasive bladder cancer found that the presence of a mutation in any one of three genes, all known to be involved in DNA damage repair, was associated with complete pathologic response to cisplatin-based neoadjuvant chemotherapy as measured by pathological downstaging at the time of bladder surgery.

29 Jul 2024

Physical activity and positive affect boost cognition in women with fibromyalgia despite pain

Researchers found that physical activity and positive affect can improve cognitive performance in women with fibromyalgia, even when pain severity is high. Promoting both may alleviate chronic pain's impact on cognition.

29 Jul 2024

Wearable, non-invasive device can measure activity in human cervical nerves in clinical settings

A research team led by UC San Diego has, for the first time, shown that a wearable, non-invasive device can measure activity in human cervical nerves in clinical settings.

29 Jul 2024

Motor neurone disease research receives major boost through new data catalyst initiative

Research into the life-shortening neurological condition motor neurone disease (MND) will receive a major boost through the formation of a new data catalyst led by Health Data Research UK (HDR UK) and Dementia Platforms UK (DPUK).

29 Jul 2024

New zwitterionic polyion developed for effective plasmid DNA delivery in muscle cells

Researchers from Tokyo Metropolitan University have created a new drug delivering molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RNA and proteins.

28 Jul 2024

Study finds body composition impacts neurodegenerative disease risk

Research reveals body composition patterns can influence the risk of neurodegenerative diseases, with certain patterns linked to increased risk due to cardiovascular disease.

28 Jul 2024

Scientists explore early life factors contributing to SMA

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists at DZNE and the Dresden University of Technology are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies of so-called organoids: Laboratory-grown tissue cultures that can reconstruct disease processes. Their findings are published in the journal Cell Reports Medicine.

27 Jul 2024

Are your ‘takeaway’ coffees exceeding daily recommended levels for caffeine intake?

The caffeine content in various popular coffee servings to assess their safety regarding recommended daily intake limits.

26 Jul 2024

Study reveals enhanced electron transport in folded peptides

What puts the electronic pep in peptides? A folded structure, according to a new study in the Proceedings of the National Academy of Sciences.

26 Jul 2024

UK initiative aims to transform MND research through health data collaboration

MND is a devastating disease affecting the motor neurones in the brain and spinal cord, leading to progressive muscle weakness and paralysis.

25 Jul 2024

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego -; a discovery that could lead to therapies for patients with other neurological conditions.

25 Jul 2024

Stanford's muscle chips reveal microgravity's impact on muscle regeneration

A gentle rumble ran under Ngan Huang's feet as a rocket carrying her research-;live, human muscle cells grown on scaffolds fixed on tiny chips-;lifted off, climbed, and disappeared into the sky to the International Space Station National Laboratory.

25 Jul 2024

Tiny titin mutation linked to developmental heart defects and adult atrial fibrillation

Millions of adults have atrial fibrillation -; an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.

25 Jul 2024

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

24 Jul 2024

High belly and arm fat linked to Alzheimer's and Parkinson's risk

People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to a study published in the July 24, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

24 Jul 2024

Lifestyle and socioeconomic status affect health impacts of ultra-processed foods

A recent study found that lifestyle and socioeconomic factors influence the negative impact of ultra-processed foods (UPF) on health-related quality of life (HRQoL). Higher UPF intake is linked to poorer physical health, especially among women, smokers, and those with low socioeconomic status.

24 Jul 2024

GeneMAP: A new tTool for mapping metabolic gene functions

There's a glaring gap in our knowledge of cell metabolism: in many cases, we still don't know exactly how nutrients are transported into the cell.

23 Jul 2024

Obese children infected with dengue appear to be at higher risk of hospitalization

Very overweight children infected with dengue appear to be at higher risk of hospitalization, according to researchers who say more public awareness is needed about the risks of obesity and severe disease.

23 Jul 2024

Muscle News and Research

Propofol shows potential for treating epilepsy and neurological disorders

Weight loss guaranteed! But what impact on your diet? A review of GLP-1 and GIP/GLP-1 interventions

DNA repair gene mutations predict bladder cancer response to neoadjuvant chemotherapy

Physical activity and positive affect boost cognition in women with fibromyalgia despite pain

Wearable, non-invasive device can measure activity in human cervical nerves in clinical settings

Motor neurone disease research receives major boost through new data catalyst initiative

New zwitterionic polyion developed for effective plasmid DNA delivery in muscle cells

Study finds body composition impacts neurodegenerative disease risk

Scientists explore early life factors contributing to SMA

Are your ‘takeaway’ coffees exceeding daily recommended levels for caffeine intake?

Study reveals enhanced electron transport in folded peptides

UK initiative aims to transform MND research through health data collaboration

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

Stanford's muscle chips reveal microgravity's impact on muscle regeneration

Tiny titin mutation linked to developmental heart defects and adult atrial fibrillation

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

High belly and arm fat linked to Alzheimer's and Parkinson's risk

Lifestyle and socioeconomic status affect health impacts of ultra-processed foods

GeneMAP: A new tTool for mapping metabolic gene functions

Obese children infected with dengue appear to be at higher risk of hospitalization

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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