Muscle Wasting News and Research

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Treatment for muscle wasting improved survival in pre-clinical cancer model

Researchers from the University of Jyväskylä in Finland have found that continued treatment of muscle wasting with a soluble growth factor receptor protein, produced at the University of Helsinki, improved survival in a pre-clinical cancer model without affecting the tumor size.

15 May 2018

Resistance training enhances cellular recycling in muscle cells

A new study has shown that resistance training among previously untrained men increases autophagosome content, but that this effect may be blunted by aging.

9 Apr 2018

Mice getting a new lease of life with anti-aging pills

According to a new study from the researchers at Harvard Medical School and the University of New South Wales, the actually cellular processes that cause aging of the blood vessels have been understood.

23 Mar 2018

New study identifies key cellular mechanisms behind vascular aging in mice

We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School.

22 Mar 2018

Study identifies two genes associated with extreme nausea and vomiting during pregnancy

Most women experience some morning sickness during pregnancy, but about 2 percent of pregnant women experience a more severe form of nausea and vomiting.

21 Mar 2018

Muscle wasting of old age and ways to stop it understood in new study

According to latest research, the muscle wasting that is associated with ageing has been attributed to loss of nerves. Researchers from the Manchester Metropolitan University, The University of Manchester, The University of Waterloo in Ontario, and Central Manchester University Hospitals NHW Foundation Trust published their study findings in the latest issue of The Journal of Physiology.

13 Mar 2018

Cholesterol and other lipids in the blood play role in many diseases

Lipids are fatty molecules that play important signaling and storage roles in the body, but having an excess of some lipids, like cholesterol, is a risk factor for many metabolic diseases.

8 Feb 2018

Investigation to fight against muscular atrophy with nano-channel drug delivery implant

Extended spaceflight takes a toll on many systems within the human body, including the musculoskeletal system. An investigation aboard the International Space Station will examine a drug compound and drug delivery system aimed at preventing, slowing, or even reversing muscular breakdown, both in space and on Earth.

27 Jan 2018

Heart failure patients who have anorexia have worse prognosis

Researchers of the German Centre for Cardiovascular Research (DZHK) have discovered that patients with heart failure who have anorexia are also more affected in their physical functional capacity and have worse prognosis.

12 Jan 2018

Researchers reveal pathological mechanisms in congenital myotonic dystrophy

Myotonic dystrophy (DM) is the most common form of genetic muscular dystrophy that begins in adulthood. DM is characterized by progressive muscle wasting and weakness. People with this disorder often have prolonged muscle contractions (myotonic) and are not able to relax certain muscles after use.

12 Dec 2017

SLU scientists provide promising approach in designing new drugs for DMD

In a paper published in the Nature journal Scientific Reports, Saint Louis University researchers report that a new drug reduces fibrosis (scarring) and prevents loss of muscle function in an animal model of Duchenne muscular dystrophy (DMD), providing a promising approach in designing new medications for those suffering from DMD.

8 Dec 2017

Regular exercise may protect smokers from muscle loss and inflammation

Regular exercise may protect smokers from some of the negative effects associated with smoking, such as muscle loss and inflammation, according to a new study.

28 Nov 2017

New review addresses aspects of nutrition in liver transplant candidates with cirrhosis

Poor nutrition is common in patients with liver failure, or cirrhosis, and it can lead to muscle wasting, weakness, fatigue, and worse outcomes before and after patients undergo liver transplantation.

26 Oct 2017

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease.

4 Oct 2017

Cellular antennae play key role in muscle-to-fat transformation

Like it or not, as we age, our muscle cells are slowly exchanged, one by one, for fat cells. This process quickens when we injure a muscle, and an extreme form of this process is also seen in muscle-wasting diseases such as Duchenne muscular dystrophy (DMD).

13 Jul 2017

New approach could potentially prevent muscle wasting in muscular dystrophy and cancer

Monash University's Biomedicine Discovery Institute researchers have collaboratively developed a therapeutic approach that dramatically promotes the growth of muscle mass, which could potentially prevent muscle wasting in diseases including muscular dystrophy and cancer.

14 Jun 2017

Researchers discover connection between processes that keep the heart from repairing itself

Heart muscle is one of the least renewable tissues in the body, which is one of the reasons that heart disease is the leading cause of death for both men and women in the United States, according to the Centers for Disease Control and Prevention.

5 Jun 2017

Weekly doses of steroids help hasten recovery in muscle injuries

Weekly doses of glucocorticoid steroids, such as prednisone, help speed recovery in muscle injuries, reports a new Northwestern Medicine study. The weekly steroids also repaired muscles damaged by muscular dystrophy.

17 May 2017

Study unravels new clues to cause and treatment of spinal muscular atrophy

Spinal muscular atrophy, a neurodegenerative disease that causes progressive muscle wasting and paralysis, may be partly due to abnormalities in the synapses that connect sensory neurons and motor neurons, according to researchers at Columbia University Medical Center.

16 May 2017

Research sheds new light on the body's response to high salt intake

When you eat salty food, you get thirsty and drink water. Right? Maybe in the short-term, but within 24 hours, you actually get less thirsty because your body starts to conserve and produce more water.

17 Apr 2017