Myocardial Infarction News and Research

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Reviparin significantly reduces death and repeat heart attacks without increasing the risk of stroke

A major Canadian-led global study has found that an inexpensive anti-blood-clotting drug significantly reduces death and repeat heart attacks without increasing the risk of stroke.

8 Nov 2004

Early reports of thrombosis after insertion of drug-eluting stent

Authors of a research letter in this week’s issue of THE LANCET highlight how the use of drug-eluting stents (DES) may carry a risk of subsequent thrombosis if stenting is accompanied by a withdrawal of antiplatelet therapy.

21 Oct 2004

EMEA statement following withdrawal of Vioxx (rofecoxib)

EU regulators met with the marketing authorisation holder of Vioxx (rofecoxib), Merck Sharp & Dohme, on 4-5 October 2004 at the informal meeting of the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) held in Scheveningen, The Netherlands.

6 Oct 2004

Receiving a blood transfusion is associated with a greater risk of death for patients with acute coronary syndromes

The use of invasive procedures for treatment of ischemic heart disease has more than tripled in the past 2 decades and is likely to increase in high-risk patients, according to background information in the article.

5 Oct 2004

NIH opens new hospital totally dedicated to clinical research

This new hospital totally dedicated to clinical research — research involving patients — is the most significant addition to the NIH campus in more than 50 years and provides a unique opportunity for scientists, clinicians, and patients to study and conquer both chronic and acute disease in the 21st century.

22 Sep 2004

Coronary angioplasty within 24 hours of medical therapy could improve the outcome for heart-attack patients

Results of a randomised trial in this week’s issue of THE LANCET suggest that a more aggressive approach involving coronary angioplasty soon after anticlotting medical therapy is safe and could offer a better prognosis than more conservative treatment for patients who have had heart attack.

17 Sep 2004

Diabetes mellitus in acute coronary syndromes – worse for women

Diabetes is associated with worse prognosis in patients with myocardial infarction, but if there is a difference between men and women in this respect is less well known.

30 Aug 2004

Early use of aggressive statin therapy may offer some benefit for coronary patients

Statins initiated early after a patient experiences an acute coronary syndrome (ACS) event at dosages above the typical starting dose may help reduce subsequent cardiovascular events, but the high dose regimen used may increase the risk for muscle-related complications, according to the results from the Phase Z portion of the A to Z Trial released on the JAMA website today.

30 Aug 2004

High blood pressure combined with elevated LDL cholesterol more than triples risk of heart attack

High blood pressure and high LDL-cholesterol add up to more than just double trouble for heart health, a Penn State College of Medicine study reports.

30 Aug 2004

No benefit from early PCI/CABG in high risk unstable angina patients

Patients with chest pain are recognized as being at high risk of subsequent adverse cardiac events when their plasma levels of cardiac troponin are elevated as evidence of myocardial damage.

29 Aug 2004

COX2 inhibitor lumiracoxib could be an effective treatment for osteoarthritis

The use of non-selective non-steroidal anti-inflammatory drugs (NSAIDs) is widespread to reduce the pain associated with osteoarthritis; however the sideeffects of these drugs can be severe, sometimes leading to gastro-intestinal ulcer complications which account for around 7000 US and 1000 UK deaths each year.

21 Aug 2004

Embryonic stem cell therapy show benefits in rebuilding damaged heart

Despite improvements in earlier diagnosis and treatment, cardiovascular disease is far and away the leading cause of death in the U.S. and the world.

18 Aug 2004

New guidelines urge early and long-term treatment with Aldosterone blockade therapy

Patients who have had a recent heart attack with ST-elevation (ST-Elevation Myocardial Infarction, or STEMI), complicated by heart failure should be treated with aldosterone blockers according to new guidelines issued recently by the American College of Cardiology (ACC) and the American Heart Association (AHA).

17 Aug 2004

Finnish company discovers over 200 new genes

Finnish company Jurilab has announced the completion of a genome-wide scan in Acute Myocardial Infarction in the East Finland Founder Population.

12 Aug 2004

CV Therapeutics initiates approval-enabling trial of drug to treat chronic angina

CV Therapeutics has announced that it has initiated an approval-enabling study of Ranexa, which, if successful, could support approval of Ranexa for the treatment of chronic angina in a restricted patient population.

3 Aug 2004

Left atrium neasurements may predict future for heart attack patients

Ultrasound measurements of the volume of the left atrium taken soon after a heart attack can help physicians predict a patient’s five-year mortality rate, according to a new study in the July 21, 2004 issue of the Journal of the American College of Cardiology.

22 Jul 2004

Evidence is emerging that adult stem cells from bone marrow have therapeutic potential for restoring cardiac cells

Results of a randomised trial in this week’s issue of THE LANCET suggest that the transfer of adult stem cells derived from bone marrow could improve cardiac functioning after heart attack.

8 Jul 2004

New guidelines for treating heart attacks

If your chest pain worsens and lasts more than five minutes, especially if you’re short of breath, feel weak, nauseated or lightheaded, call 9-1-1—you could be having a heart attack.

8 Jul 2004

Anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes

Two new major studies suggest that anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes (ACS)

7 Jul 2004

Exercise found to be equally effective as diuretics in preventing high blood pressure and an enlarged heart

Only recently was a type of diuretic known as thiazides been found to be superior to angiotensin-converting enzyme (ACE) inhibitors and calcium antagonists (calcium channel blockers) in preventing one or more major types of cardiovascular disease.

30 Jun 2004

Myocardial Infarction News and Research

Reviparin significantly reduces death and repeat heart attacks without increasing the risk of stroke

Early reports of thrombosis after insertion of drug-eluting stent

EMEA statement following withdrawal of Vioxx (rofecoxib)

Receiving a blood transfusion is associated with a greater risk of death for patients with acute coronary syndromes

NIH opens new hospital totally dedicated to clinical research

Coronary angioplasty within 24 hours of medical therapy could improve the outcome for heart-attack patients

Diabetes mellitus in acute coronary syndromes – worse for women

Early use of aggressive statin therapy may offer some benefit for coronary patients

High blood pressure combined with elevated LDL cholesterol more than triples risk of heart attack

No benefit from early PCI/CABG in high risk unstable angina patients

COX2 inhibitor lumiracoxib could be an effective treatment for osteoarthritis

Embryonic stem cell therapy show benefits in rebuilding damaged heart

New guidelines urge early and long-term treatment with Aldosterone blockade therapy

Finnish company discovers over 200 new genes

CV Therapeutics initiates approval-enabling trial of drug to treat chronic angina

Left atrium neasurements may predict future for heart attack patients

Evidence is emerging that adult stem cells from bone marrow have therapeutic potential for restoring cardiac cells

New guidelines for treating heart attacks

Anticoagulant therapy with enoxaparin is an effective alternative to heparin therapy for patients with acute coronary syndromes

Exercise found to be equally effective as diuretics in preventing high blood pressure and an enlarged heart

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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