Myopathy News and Research

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The myopathies are neuromuscular disorders in which the primary symptom is muscle weakness due to dysfunction of muscle fiber. Other symptoms of myopathy can include include muscle cramps, stiffness, and spasm. Myopathies can be inherited (such as the muscular dystrophies) or acquired (such as common muscle cramps).

What are the risk factors associated with post-acute SARS-CoV-2 infection?

In a recent study posted to the Research Square* preprint server, researchers assessed the risk factors and predictive models for post-acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

13 Mar 2023

In-depth assessment of muscle biopsies in patients with long COVID

Researchers analyzed skeletal muscle biopsies of patients with persistent fatigue and malaise post-exertion to determine the underlying mechanisms of long COVID.

20 Feb 2023

MIS-C more common and severe than previously thought

In a recent study published in the JAMA Network Open journal, researchers compared the characteristics of multisystem inflammatory syndrome in children (MIS-C) and coronavirus disease 2019 (COVID-19).

10 Jan 2023

Analyzing electronic medical records to identify COVID-19 sequelae

In a recent study published in the journal Emerging Infectious Diseases, researchers analyzed and compared pre‒ and post‒COVID-19 diagnostic codes to identify symptoms that had higher encounter incidence in the post‒COVID-19 period as sequelae. COVID-19 sequelae and future emerging diseases can be generated and monitored using this method.

3 Jan 2023

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this “starvation response” is triggered, and what can inhibit it.

15 Dec 2022

The health status and exercise capacity of COVID-19 survivors one year after hospital discharge

A recent study evaluated the health status and exercise capacity of COVID-19-recovered patients one year after hospital discharge.

13 Oct 2022

The effects and mechanisms of SARS-CoV-2 on the nervous system

Researchers reviewed the neurologic manifestations associated with SARS-CoV-2.

30 Jun 2022

Simplicity is key when it comes to ablation, global AFib study finds

Results from one of the largest global studies of atrial fibrillation (AFib) procedures show that the simple approach is usually best when it comes to ablation, a procedure where physicians destroy or ablate cardiac tissue to correct irregular heart rhythms.

21 Jun 2022

New HSS study clarifies the clinical manifestations of undifferentiated connective tissue disease

A new study by researchers at Hospital for Special Surgery (HSS) has further clarified the clinical manifestations of undifferentiated connective tissue disease (UCTD).

2 Jun 2022

The involvement of the skeletal muscles in long COVID-19

Researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long COVID‐19.

18 Apr 2022

Researchers present a possible therapeutic approach for severe congenital myopathy

The diagnosis is rare, but devastating – children with congenital muscle disorders often never learn to walk. Until now, there was no chance of recovery, but researchers at the University of Basel and University Hospital Basel are now presenting a possible therapeutic approach for the first time.

29 Mar 2022

Visual ultrasound of the heart helps identify novel measures linked to a higher dementia risk

Published in JAMA, research from the University of Minnesota assessed if there is a link between heart health and dementia.

23 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Study helps understand actionable genetic variation affecting drugs in the Middle East population

A group of researchers at Qatar Foundation have reported the first comprehensive study of the distribution of actionable genetic variation affecting drugs in any Middle Eastern population, with potential implications for preemptive pharmacogenomic implementation in the region.

16 Feb 2022

Looking into the long-COVID brain

Neurological issues, ranging from memory lapses to trouble with attention, have been widely reported after recovery from severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection. Unfortunately, there is limited information about pathways to recovery after severe COVID hospitalization. Now, a prospective study of 4,491 patients hospitalized with COVID suggests neurological recovery can take at least a year. The study is currently available on the medRxiv* preprint while awaiting peer review.

13 Feb 2022

Myopathy News and Research

Further Reading

What are the risk factors associated with post-acute SARS-CoV-2 infection?

In-depth assessment of muscle biopsies in patients with long COVID

MIS-C more common and severe than previously thought

Analyzing electronic medical records to identify COVID-19 sequelae

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

The health status and exercise capacity of COVID-19 survivors one year after hospital discharge

The effects and mechanisms of SARS-CoV-2 on the nervous system

Simplicity is key when it comes to ablation, global AFib study finds

New HSS study clarifies the clinical manifestations of undifferentiated connective tissue disease

The involvement of the skeletal muscles in long COVID-19

Researchers present a possible therapeutic approach for severe congenital myopathy

Visual ultrasound of the heart helps identify novel measures linked to a higher dementia risk

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

Novel molecular pathway shared by two neurodegenerative disorders discovered

Study helps understand actionable genetic variation affecting drugs in the Middle East population

Looking into the long-COVID brain

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

A case of post-vaccination MIS in an adult without prior SARS-CoV-2 infection

Peripheral nerve injuries and severe COVID-19

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Snapping at new biotech breakthroughs with Gator Pro

Realizing the Importance of Medical Electronic Devices

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