Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Assessing exposure to airborne nanomaterials

New methods and tools for measuring exposure to airborne engineered nanomaterials will be required to protect the health of workers in nanotechnology-related jobs, estimated to total 10 million people by 2014, according to two occupational health experts writing in the inaugural issue of the journal Nanotoxicology.

18 Apr 2007

Nanoparticles could damage DNA and lead to cancer

Tissue studies indicate that nanoparticles, engineered materials about a billionth of a meter in size, could damage DNA and lead to cancer, according to research presented at the 2007 Annual Meeting of the American Association for Cancer Research.

18 Apr 2007

Nanoparticle delivery system delivers cancer-suppressing gene in M. D. Anderson trial

A cancer-suppressing gene has been successfully delivered into the tumors of stage 4 lung cancer patients via an intravenously administered lipid nanoparticle in a phase I clinical trial at The University of Texas M. D. Anderson Cancer Center.

18 Apr 2007

New diagnostic technologies to predict and monitor cancer risks

Molecular messages and signals circulating in blood or contained in cells lining the airway can identify early stage cancer, according to research reported at the 2007 Annual Meeting of the American Association for Cancer Research.

16 Apr 2007

Gelatin-based nanoparticles deliver therapeutic genes to human breast cancer

Northeastern University professor Mansoor Amiji and graduate student Sushma Kommareddy have published a new paper that examines the potential of engineered gelatin-based nanoparticles to deliver therapeutic genes to human breast cancer tumors implanted in mice.

14 Apr 2007

How size matters in the retention of nanomaterials in tissue

Tiny, biodegradable particles filled with medicine may also contain answers to some of the biggest human health problems, including cancer and tuberculosis.

11 Apr 2007

Cylindrical nanoparticles deliver drugs to tumors

Researchers at the University of Pennsylvania School of Medicine & School of Engineering and Applied Science have discovered a better way to deliver drugs to tumors.

7 Apr 2007

Selective binding of gold nanoparticles to the ends of rod-shaped viruses

Nanotechnology appears to be an unstoppable trend and it requires defined nanoscale building blocks and patterns.

5 Apr 2007

Intelligent materials substitute for bone tissue

More than half a million people in the European Union and a million in the United States suffer from disorders in or serious defects of some part of their bone structure.

2 Apr 2007

Iron nanoparticles exhibit toxic effects on neuronal cells

Researchers at UC San Diego have discovered that iron-containing nanoparticles being tested for use in several biomedical applications can be toxic to nerve cells and interfere with the formation of their signal-transmitting extensions.

1 Apr 2007

Nanotechnology reveals hidden fingerprints

Hidden fingerprints can be now be revealed quickly and reliably thanks to two developments in nanotechnology.

14 Mar 2007

Scientists test 'secret weapon' against tumours

Cancer Research UK scientists in Glasgow have devised a new method of attacking cancer cells. They report the findings in the Journal of Clinical Investigation.

11 Mar 2007

Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling

Administering a small amount of a potent but potentially toxic anticancer agent along with nanoparticles loaded with a second anticancer agent produced a dramatic inhibition of tumor growth in normally intractable cancers. These findings suggest a new approach to treating malignancies such as pancreatic cancer and diffuse gastric cancer.

5 Mar 2007

Targeted nanoparticles image early tumors

A well-established fact in cancer therapy is that early tumor detection improves the odds that a patient will survive the disease. Now, using nanoparticles targeted to the tiny blood vessels that surround even the smallest tumors, researchers at the Siteman Center for Cancer Nanotechnology Excellence (CCNE) have developed a radioactive imaging agent that was able to identify human tumors in rabbits.

5 Mar 2007

Ultrafine hydrogel nanoparticles: synthetic approach and therapeutic application in living cells

Ultrafine nanoparticles made of a lacy web of polymer and tiny pockets of water may prove to be an ideal vehicle for delivering light-activated drugs to tumors.

5 Mar 2007

Quantum rods and dots image cancer cells

Brightly fluorescent quantum dots and quantum rods are quickly becoming important tools for identifying specific molecules and cells in living systems. Two new reports demonstrate some of the ways in which cancer researchers are using these nanoscale imaging agents.

26 Feb 2007

Perfluorocarbon nanoparticles track living cells

Stem cell therapy, primarily bone marrow transplantation, plays a key role in treating leukemia and other types of cancer.

26 Feb 2007

Nanoparticles advance photodynamic therapy to kill tumor cells

Photodynamic therapy (PDT) is a powerful approach for destroying tumors, one that uses light and a light-sensitive chemical to rapidly kill cells.

20 Feb 2007

Nanoparticles rely on 'velcro effect' to target tumor cells

One of the basic tenets of targeted nanoparticle drug delivery is putting multiple targeting molecules on a nanoparticle surface will improve the ability of nanoparticles to stick to their targeted cell and deliver their drug cargos to the appropriate diseased cell.

20 Feb 2007

All types of carbon nanotubes penetrate wide variety of cell membranes

Over the past two years, researchers have demonstrated repeatedly that certain types of carbon nanotubes are among the most effective materials known for transporting proteins, genes, and drug molecules across the cell membrane.

20 Feb 2007

Nanoparticle News and Research

Further Reading

Assessing exposure to airborne nanomaterials

Nanoparticles could damage DNA and lead to cancer

Nanoparticle delivery system delivers cancer-suppressing gene in M. D. Anderson trial

New diagnostic technologies to predict and monitor cancer risks

Gelatin-based nanoparticles deliver therapeutic genes to human breast cancer

How size matters in the retention of nanomaterials in tissue

Cylindrical nanoparticles deliver drugs to tumors

Selective binding of gold nanoparticles to the ends of rod-shaped viruses

Intelligent materials substitute for bone tissue

Iron nanoparticles exhibit toxic effects on neuronal cells

Nanotechnology reveals hidden fingerprints

Scientists test 'secret weapon' against tumours

Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling

Targeted nanoparticles image early tumors

Ultrafine hydrogel nanoparticles: synthetic approach and therapeutic application in living cells

Quantum rods and dots image cancer cells

Perfluorocarbon nanoparticles track living cells

Nanoparticles advance photodynamic therapy to kill tumor cells

Nanoparticles rely on 'velcro effect' to target tumor cells

All types of carbon nanotubes penetrate wide variety of cell membranes

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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