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Nanoparticle that delivers vaccines more effectively

Good news for public health: Bioengineering researchers from the EPFL in Lausanne, Switzerland, have developed and patented a nanoparticle that can deliver vaccines more effectively, with fewer side effects, and at a fraction of the cost of current vaccine technologies.

18 Sep 2007

New material for joint replacement and other implants

For orthopaedic implants to be successful, bone must meld to the metal that these artificial hips, knees and shoulders are made of.

18 Sep 2007

Federal plan to determine nanotech risks fails to deliver

Almost a year in the making, a federal plan to prioritize research on the potential environmental, health, and safety (EHS) impacts of nanoscale materials has so many failings that its begs the question as to whether the government's 13-agency nanotechnology research effort is able to deliver an effective risk research strategy, according to David Rejeski, head of the Wilson Center's Project on Emerging Nanotechnologies.

13 Sep 2007

DNA and nanotechnology

DNA is one of the most popular building blocks of nanotechnology and is commonly used to construct ordered nanoscale structures with controlled architectures.

5 Sep 2007

Nanotechnology helps identify molecular signature common to Lou Gehrig's disease

A nanotechnology developed by a University at Buffalo professor has enabled researchers to identify a molecular signature common to both familial and sporadic cases of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease.

5 Sep 2007

Secret to bone's strength

Scientists and engineers are eager to understand the secret behind bone's lightweight toughness so they can mimic it in the design of new materials, but previous studies have revealed a number of different strength mechanisms at different scales of focus, rather than a single theory.

28 Aug 2007

Scientist uses novel mass spectrometer to weigh virus particle

With unprecedented sensitivity, Carnegie Mellon University's Mark Bier has characterized large viral particles and bulky von Willebrand factors using a novel mass spectrometer.

24 Aug 2007

Cell-based sensor for analysis of EGFR biomarker expression in oral cancer

Using a microfluidic device designed to capture and enrich cells from biological samples, a research team at The University of Texas at Austin has developed a test that can detect an important early marker for oral squamous cell carcinoma, which accounts for more than 90 percent of oral cancers. Oral cancer is the sixth most common cancer worldwide and is difficult to detect early enough to treat successfully.

22 Aug 2007

Antitumour drugs impede DNA uncoiling by topoisomerase I

The annoying bulges of an overwound telephone cord that shorten its reach and limit a caller's motion help explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators led by Mary-Ann Bjornsti, Ph.D., at St. Jude Children’s Research Hospital, and Nynke Dekker, Ph.D., at Delft Technology University.

22 Aug 2007

Near-infrared resonant nanoshells for combined optical imaging and photothermal cancer therapy

Using metal nanoshells designed to both absorb and scatter near-infrared light, a team of investigators at Rice University has shown that such nanoparticles can both image and treat tumors in animals. Their experiments revealed complete tumor destruction in more than 80 percent of animals treated with these nanoshells.

22 Aug 2007

Nanotubes offer new approach to cancer radiotherapy

Radioactive elements, or radionuclides, are well-established anticancer agents whose main limitation is that they kill healthy cells almost as easily as they do tumors. But because nanoparticles can be targeted to tumors, researchers have seized on the idea of using nanoparticles to deliver radionuclides to tumors, thus sparing healthy tissues from radiation-induced damage.

22 Aug 2007

Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy

A new targeted drug delivery method, which combines two nanoparticles into one larger one, uses ultrasound to image tumors and release the anticancer drug doxorubicin from "nanobubbles" into the same tumors.

22 Aug 2007

Targeted quantum dot conjugates for siRNA delivery

Take a quantum dot, add a coating of poly(ethylene glycol) (PEG), and attach a homing peptide and a piece of small interfering RNA (siRNA), and the result is a targeted nanoparticle that can stop the production of a specific protein by a targeted cell.

22 Aug 2007

Nanotech sensors and tiny transmitters to predict and prevent epileptic seizures

Purdue University researchers have developed new miniature devices designed to be implanted in the brain to predict and prevent epileptic seizures and a nanotech sensor for implantation in the eye to treat glaucoma.

8 Aug 2007

Foodborne illness and fresh produce

Once was the day that beef was considered a primary source of foodborne illness.

2 Aug 2007

Consumer food trends

Rose petals and orange blossoms are turning up in yogurt and the newest drinks touting antioxidants double as high-octane cocktail mixers.

2 Aug 2007

Nanoparticles may provide safe pain control on the battlefield

University of Michigan scientists have received a pilot grant of nearly $1.3 million from the Defense Advanced Research Projects Agency to test whether nanoparticles can solve a pressing problem in battle zones like Iraq: how to administer sustained, safe doses of the most effective painkillers to injured soldiers, long before they can reach expert medical help.

1 Aug 2007

Gold nanoparticles for cancer diagnosis

When it comes to searching out cancer cells, gold may turn out to be a precious metal.

1 Aug 2007

Baby boomers are starting to feel the aches, pains and weight gain of aging

Because they, like others, want to feel younger for longer, food companies and food researchers are striving to meet their needs. Increased amounts of nutritional supplements and antioxidants, including calcium, vitamin D and zinc, can slow the rate of age-related disease and increase the number of healthy years, according Jeffrey Blumberg, a nutrition scientist at Tufts University and speaker here at the Institute of Food Technologists Annual Meeting & Food Expo.

1 Aug 2007

New St. Jude alliance with San Diego institutions helps advance fight against cancer

St. Jude Children's Research Hospital continues to define the forefront of clinical care and research by announcing the creation of a new alliance with two Southern California institutions: Rady Children's Hospital, San Diego; and the University of California, San Diego (UCSD).

1 Aug 2007