Narcolepsy News and Research

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Narcolepsy is a chronic sleep disorder, or dyssomnia. The condition is characterized by excessive daytime sleepiness (EDS) in which a person experiences extreme fatigue and possibly falls asleep at inappropriate times, such as while at work or at school.

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Two powerful brain chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to new research in the July 11 issue of The Journal of Neuroscience. The finding may help scientists better understand and treat sleep disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder.

12 Jul 2012

Health risks associated with H1N1 vaccine investigated

Results from two studies published in JAMA show that the H1N1 vaccination is associated with a small, but significant, increase in risk for Guillain-Barré syndrome in adults, but does not increase the risk for birth defects or problems when given to pregnant women.

11 Jul 2012

Violence affects a child's quality and quantity of sleep

When violence shatters a child's world, the torment can continue into their sleep, according to researchers in Cleveland. The impact is measurable and affected by the severity of the violence, and the effects can last over time.

14 Jun 2012

Investigational Insomnia Medicine from Merck improved patients’ ability to fall and stay asleep according to new phase III Data

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced new data from two pivotal Phase III efficacy trials for suvorexant, the investigational medicine Merck is developing for the treatment of insomnia. In the studies, suvorexant significantly reduced the time it took patients to fall asleep and increased the time that patients stayed asleep as early as the first night and at the three-month time point compared to placebo. The investigational medicine met statistical significance for all primary endpoints except for one measurement at Month 3 in one of the trials. These late-breaking data were presented here today at SLEEP 2012, the 26th Annual Meeting of the Associated Professional Sleep Societies.

13 Jun 2012

Another benefit of CPAP therapy for men with OSA

Men who suffer from obstructive sleep apnea (OSA) are seeing another potential benefit from continuous positive airway pressure therapy, or CPAP: improved sexual function and satisfaction in non-diabetic men under age 60.

13 Jun 2012

Two studies report sleep disparities among Americans based on racial and ethnic background

Two studies scheduled for presentation today at SLEEP 2012 are reporting sleep disparities among Americans based on racial and ethnic background.

13 Jun 2012

Researchers encourage PCPs to screen for OSA in patients with Type 2 diabetes

Researchers in New Jersey are encouraging primary care physicians to screen for obstructive sleep apnea (OSA) in patients with Type 2 diabetes. They found that in a small sample of clinic patients, the risk for sleep apnea was high among diabetics compared with non-diabetics, and that sleep apnea appeared to be associated with carbohydrate craving.

13 Jun 2012

Depression, obesity two main culprits of excessive daytime sleepiness

Wake up, America, and lose some weight - it's keeping you tired and prone to accidents. Three studies being presented today at sleep 2012 conclude that obesity and depression are the two main culprits making us excessively sleepy while awake.

13 Jun 2012

OSA negatively impacts youths’ ability to regulate life skills

The number of children with obstructive sleep apnea (OSA) declines as they enter adolescence, but the teen years can be a devastating trial of behavior and learning problems for kids with persistent OSA, new research shows.

12 Jun 2012

Positive airway pressure reduces depressive symptoms in patients with OSA

Patients seen at the Cleveland Clinic Sleep Disorders Center who used positive airway pressure (PAP) to treat their obstructive sleep apnea (OSA) had improvements in their depressive symptoms, even if they followed the prescribed PAP regimen only partly, a new study reports.

12 Jun 2012

Researcher uncovers link between pro athlete's longevity and sleepiness

Coaches, owners and fantasy-league traders take note: Sleep researcher W. Christopher Winter, MD, has uncovered a link between a pro athlete's longevity and the degree of sleepiness experienced in the daytime.

12 Jun 2012

Adult fear of the dark may contribute to insomnia

A small study of Toronto college students is shedding light on a contributing factor of insomnia that might be hard to admit - an adult fear of the dark.

11 Jun 2012

Short sleep periods increase risk of stroke in normal-weight adults

Habitually sleeping less than six hours a night significantly increases the risk of stroke symptoms among middle-age to older adults who are of normal weight and at low risk for obstructive sleep apnea (OSA), according to a study of 5,666 people followed for up to three years.

11 Jun 2012

MRI scans reveal how sleep deprivation impairs brain regions associated with food processing

MRI scans from a study being presented today at SLEEP 2012 reveal how sleep deprivation impairs the higher-order regions in the human brain where food choices are made, possibly helping explain the link between sleep loss and obesity that previous research has uncovered.

11 Jun 2012

Study uses brain scans to better understand link between sleep restriction and obesity

The sight of unhealthy food during a period of sleep restriction activated reward centers in the brain that were less active when participants had adequate sleep, according to a new study using brain scans to better understand the link between sleep restriction and obesity.

11 Jun 2012

Sleep loss markedly exaggerates emotional reactivity in people with anxiety disorders

New research shows that sleep loss markedly exaggerates the degree to which we anticipate impending emotional events, particularly among highly anxious people, who are especially vulnerable.

11 Jun 2012

Mylan, Teva resolve generic Provigil litigation

Mylan Inc. today announced that its subsidiary Mylan Pharmaceuticals Inc. has resolved all disputes with Teva Pharmaceuticals USA, Inc. stemming from litigation brought by Mylan in federal court in the District of Columbia against the U.S. Food and Drug Administration (FDA) concerning Mylan's abbreviated new drug application (ANDA) for Modafinil Tablets, 100 mg and 200 mg.

8 Jun 2012

With Adderall shortage, drug counterfeiters try to seize a market opportunity

A shortage of Adderall began last year, sending millions of people with attention deficit/hyperactivity disorder and narcolepsy on perpetual wild goose chases to find drugstores with the pills they need to stay alert and focused. So it's not surprising that Adderall counterfeiters have seized a big marketing opportunity. What is surprising is their clumsiness.

31 May 2012

Ritalin use in ADHD rises four-fold over a decade

According to latest figures prescriptions for Ritalin for attention deficit hyperactivity disorder (ADHD) have quadrupled in a decade. This has raised concerns that it is being given to children at the expense of alternative treatments and without appreciation of long-term effects.

8 May 2012

Teva, Mylan settle patent infringement litigation for Nuvigil

Teva Pharmaceutical Industries Ltd., one of the world's largest producers of pharmaceuticals, announces that it has settled patent infringement litigation regarding U.S. Patent Number 7,132,570 (the "'570 patent") with respect to Mylan Inc.'s ANDA for Teva's wakefulness product NUVIGIL (armodafinil) tablets.

30 Apr 2012

Narcolepsy News and Research

Further Reading

Powerful brain chemical systems work together to paralyze skeletal muscles during REM sleep

Health risks associated with H1N1 vaccine investigated

Violence affects a child's quality and quantity of sleep

Investigational Insomnia Medicine from Merck improved patients’ ability to fall and stay asleep according to new phase III Data

Another benefit of CPAP therapy for men with OSA

Two studies report sleep disparities among Americans based on racial and ethnic background

Researchers encourage PCPs to screen for OSA in patients with Type 2 diabetes

Depression, obesity two main culprits of excessive daytime sleepiness

OSA negatively impacts youths’ ability to regulate life skills

Positive airway pressure reduces depressive symptoms in patients with OSA

Researcher uncovers link between pro athlete's longevity and sleepiness

Adult fear of the dark may contribute to insomnia

Short sleep periods increase risk of stroke in normal-weight adults

MRI scans reveal how sleep deprivation impairs brain regions associated with food processing

Study uses brain scans to better understand link between sleep restriction and obesity

Sleep loss markedly exaggerates emotional reactivity in people with anxiety disorders

Mylan, Teva resolve generic Provigil litigation

With Adderall shortage, drug counterfeiters try to seize a market opportunity

Ritalin use in ADHD rises four-fold over a decade

Teva, Mylan settle patent infringement litigation for Nuvigil

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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