Nephrologist News and Research

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Scientists develop new class of drugs to treat hereditary kidney disease

Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure.

18 Jun 2019

Indigestion remedy improves survival in people with late-stage CKD

Defined as serum bicarbonate less than 22 mmol/L, metabolic acidosis is common in people with CKD stages 4-5 (eGFR < 30 ml/min/1.73 m2) and is directly related to worsening kidney function.

17 Jun 2019

Study links heartburn drugs to fatal cases of heart, kidney disease and gastrointestinal cancer

Extended use of popular drugs to treat heartburn, ulcers and acid reflux has been associated with an increased risk of premature death. However, little has been known about the specific causes of death attributed to the drugs.

30 May 2019

Changes to Medicare rules could support care innovation for dialysis

In a commentary published in the American Journal of Kidney Diseases, public health researchers suggest adjustments to recently proposed rule changes on how Medicare pays for dialysis services.

22 Apr 2019

More care is needed for patients after kidney transplantations, reports research

Patients with chronic kidney disease, and dialysis patients especially, have a significantly higher cardiovascular morbidity and mortality than healthy people. Kidney transplantation is the best renal replacement therapy available.

19 Apr 2019

Excessive vitamin D intake causes man to develop kidney failure

A case study recently published in the Canadian Medical Association Journal has highlighted the danger of taking too many vitamin D supplements.

9 Apr 2019

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.

25 Mar 2019

Listening to older patients who want to stop dialysis

Dr. Susan Wong sat down with an 84-year-old patient in the hospital, where he'd been admitted with a flare-up of a serious autoimmune condition and deteriorating kidney function.

28 Feb 2019

Excessive suppression of GSK3 enzyme can trigger renal failure, finds study

Scientists have identified an enzyme that is a "master regulator" of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals.

24 Jan 2019

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future.

16 Nov 2018

Newly designed mice emulate severe form of kidney damage in humans with diabetes

Scientists led by Duke-NUS Medical School have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy.

9 Nov 2018

Research reveals new ways to better protect the kidneys from essential imaging tests

Every year millions of people undergo medical tests and procedures, such as coronary angiography, which use intravascular contrast dyes.

12 Oct 2018

Spurred by convenience, millennials often spurn the ‘family doctor’ model

Calvin Brown doesn’t have a primary care doctor — and the peripatetic 23-year-old doesn’t want one.

9 Oct 2018

Wits doctors transplant liver from HIV positive mother to her child with end-stage liver disease

This was the ethical dilemma faced by doctors at Wits Donald Gordon Medical Centre to save a child's life.

4 Oct 2018

Experts call for more transparency about joint-venture ownership of dialysis clinics

Penn Medicine experts in nephrology and health policy call for more transparency about joint-venture ownership of dialysis clinics to better understand what impact these arrangements may have on patient referrals and clinical outcomes.

4 Oct 2018

Inequality issues persist even under new U.S. kidney transplant allocation system

The implementation of a new U.S. kidney transplant allocation system did not solve many of the inequities that low-income and minority kidney disease patients face, Drexel University College of Medicine researchers found in a new study published recently in the journal Clinical Transplantation.

18 Sep 2018

Study: Air pollution can fuel chronic kidney disease

There is good evidence that polluted air increases the risk of respiratory problems such as asthma -- as well as organ inflammation, worsening of diabetes and other life-threatening conditions.

25 Aug 2018

Intensive blood pressure control may pose risk for serious falls and fainting, shows study

Kaiser Permanente research published today in the American Journal of Preventive Medicine found if patients with hypertension taking prescribed medications experience unusually low blood pressures -- systolic blood pressure under 110mmHg -- they are twice as likely to experience a fall or faint as patients whose treated blood pressure remains 110mmHg and above.

25 Aug 2018

Biologic, environmental factors may be possible culprits for racial disparities in CKD progression

Although black and Hispanic veterans with chronic kidney disease are more likely than white patients to see a kidney specialist- a nephrologist- they are more likely to suffer disease progression from early stage to advanced kidney disease, reports a study published this month in the Journal of the American Society of Nephrology from researchers at the Perelman School of Medicine at the University of Pennsylvania.

24 Aug 2018

Federal grant extends and expands research into acute kidney failure

The National Institute of Diabetes and Digestive and Kidney Diseases has renewed a grant shared by the University of Alabama at Birmingham School of Medicine and the University of California at San Diego School of Medicine that will extend and expand research into acute kidney failure, or acute kidney injury, which affects about 1.2 million hospitalized patients per year and kills 70 to 80 percent of patients in intensive care units who develop the disease.

22 Aug 2018