Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Liraglutide drug effectively decreases cardiovascular disease risk in type 2 diabetes patients

Researchers have shown that the glucose-lowering drug liraglutide safely and effectively decreases the overall risk of heart attack, stroke, or cardiovascular death for people with type 2 diabetes.

14 Jun 2016

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

A study in the Journal of the American Society of Nephrology suggests a new therapeutic approach to treat the development of chronic kidney disease secondary to chronic heart failure, known as cardiorenal syndrome type 2.

14 Jun 2016

'Hypertensive urgency' may cause unnecessary alarm

Patients with a very high blood pressure reading in the absence of other symptoms are highly unlikely to have a major adverse cardiovascular event within the next 6 months, researchers report.

14 Jun 2016

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

While hospitalizations related to rheumatoid arthritis have dropped considerably over the past two decades, hospitalizations primarily associated with gout have increased dramatically.

8 Jun 2016

Overtesting for HbA1C levels can increase risk of severe hypoglycemia

With a more-is-better mindset common in society, frequent commercials encouraging checks of glycated hemoglobin (HbA1C) levels, and ads for new diabetes medications to lower HbA1C in adults with Type 2 diabetes, Mayo Clinic researchers were not too surprised to find overtesting occurring.

7 Jun 2016

Drinking soft drinks to rehydrate worsens dehydration-related kidney injury

Repeated heat-related dehydration has been associated with increased risk of chronic kidney damage in mice. A new study in rats published in the American Journal of Physiology—Regulatory, Integrative and Comparative Physiology reports that drinking soft drinks to rehydrate worsened dehydration and kidney injury.

7 Jun 2016

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

Research into kidney regeneration, an organ that has been extremely difficult to regenerate, has taken a great stride forward with research coming out of a collaboration between Kumamoto University, Japan and the National Cancer Institute of the US.

7 Jun 2016

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Testing for a common genetic variant may help reveal which patients face an increased risk of developing kidney damage following heart surgery. The findings, which come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology, may help investigators develop therapeutic strategies to mitigate this damage.

3 Jun 2016

$Sostdc1 gene may play vital role in fracture healing process$

Sostdc1 gene may play vital role in fracture healing process

New identification of a gene involved in the fracture healing process could lead to the development of new therapeutic treatments for difficult-to-heal injuries.

2 Jun 2016

Combining VCA with organ transplants improves patient outcomes

Simultaneous transplantation of a "composite" skull and scalp flap plus a kidney and pancreas—all from the same donor—provided excellent outcomes for a patient with a non-healing scalp defect and declining organ kidney and pancreas function, according to a report in the June issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

28 May 2016

CKD status does not affect health status outcomes after AMI

Chronic kidney disease does not accentuate the decline in health status often experienced by patients after acute myocardial infarction, US study data show.

27 May 2016

Accumulation of gut bacterial metabolite may lead to serious health problems in CKD patients

In patients with chronic kidney disease (CKD), the accumulation of a gut bacterial metabolite that's normally excreted in urine may contribute to serious health problems. The findings come from a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

27 May 2016

Majority of young adults with abdominal obesity unaware of CKD risk

Many young adults with abdominal obesity exhibit a readily detectable risk factor for chronic kidney disease (CKD), yet the vast majority don't know they're at risk, according to a study of nationwide health data led by Albert Einstein College of Medicine researchers that was published online today in the journal PLOS ONE.

26 May 2016

Sodium excretion linked to CVD risk in chronic kidney disease

High levels of sodium excretion are associated with a significantly increased risk of cardiovascular disease in patients with chronic kidney disease (CKD), US study findings indicate.

26 May 2016

Study finds link between sodium intake and clinical CVD events in CKD patients

In a study appearing in the May 24/31 issue of JAMA, Jiang He, M.D., Ph.D., of the Tulane University School of Public Health and Tropical Medicine, New Orleans, and colleagues evaluated more than 3,500 participants with chronic kidney disease (CKD), examining the association between urinary sodium excretion and clinical cardiovascular disease (CVD) events.

25 May 2016

Chloride switch controls critical step in basement membrane formation

Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body.

24 May 2016

Study: One-third of patients hospitalised with heart failure do not return to work

One-third of patients hospitalised with heart failure for the first time have not returned to work one year later, reveals a study in nearly 12 000 patients presented today at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure by Dr Rasmus Roerth, a physician at Copenhagen University Hospital in Copenhagen, Denmark.

23 May 2016

SeeKD targeted screening program helps early detection of CKD risk in Canadians

A screening program for chronic kidney disease (CKD) initiated in Canada has successfully identified a high proportion of individuals with risk factors for CKD as well as many with unrecognized CKD.

20 May 2016

Combined public health intervention could help manage CKD in developing countries

A simple and inexpensive public health intervention helped prevent many cases of chronic kidney disease (CKD) in Pakistan. The intervention, which is described in a study in the Clinical Journal of the American Society of Nephrology, will be especially helpful for protecting the kidney health of people living in developing countries.

20 May 2016

Simple sarcopenia screening method could easily diagnose severity of heart disease

Researchers from Kumamoto University in Japan have shown that a simple screening method could quickly and easily diagnose the severity of heart disease. The method was originally developed to diagnose sarcopenia, a disease that causes a loss of muscle mass and strength.

19 May 2016

Nephropathy News and Research

Further Reading

Liraglutide drug effectively decreases cardiovascular disease risk in type 2 diabetes patients

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

'Hypertensive urgency' may cause unnecessary alarm

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

Overtesting for HbA1C levels can increase risk of severe hypoglycemia

Drinking soft drinks to rehydrate worsens dehydration-related kidney injury

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

Common genetic variant in HO-1 gene linked to AKI risk following cardiac surgery

Sostdc1 gene may play vital role in fracture healing process

Combining VCA with organ transplants improves patient outcomes

CKD status does not affect health status outcomes after AMI

Accumulation of gut bacterial metabolite may lead to serious health problems in CKD patients

Majority of young adults with abdominal obesity unaware of CKD risk

Sodium excretion linked to CVD risk in chronic kidney disease

Study finds link between sodium intake and clinical CVD events in CKD patients

Chloride switch controls critical step in basement membrane formation

Study: One-third of patients hospitalised with heart failure do not return to work

SeeKD targeted screening program helps early detection of CKD risk in Canadians

Combined public health intervention could help manage CKD in developing countries

Simple sarcopenia screening method could easily diagnose severity of heart disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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