Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and regulate the water and acid-base balance of the body; therefore, loss of kidney function is a potentially fatal condition.
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Nephropathy is considered a progressive illness; in other words, as kidneys become less and less effective over time with the progression of the disease, the condition of the patient gets worse if left untreated. This is the reason why it is pivotal to receive an adequate diagnosis and treatment as early as possible.
Diabetic nephropathy is considered a major microvascular complication of diabetes mellitus that affects approximately one-third of all diabetic patients. It usually accompanies albuminuria with glomerular hyperfiltration and renal hypertrophy in the early stage, often showing a deteriorating course that can lead to end-stage renal failure.