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Disruption of normal gene interaction linked to schizophrenia

Disruption of the normal interaction between the genes PRODH and COMT contributes directly to major symptoms of schizophrenia by upsetting the balance of the brain chemicals glutamate and dopamine, according to a group of investigators that includes a scientist now at St. Jude Children's Research Hospital.

2 Dec 2005

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

Scientists at the Johns Hopkins Kimmel Cancer Center have found that a gene pathway linked to a deadly form of leukemia may provide a new way to treat autoimmune diseases, including multiple sclerosis.

2 Dec 2005

Bisphenol A (BPA) has been linked to damage in developing brain tissue

The chemical bisphenol A (BPA), widely used in products such as food cans, milk container linings, water pipes and even dental sealants, has now been found to disrupt important effects of estrogen in the developing brain.

2 Dec 2005

Cole Porter was wrong - love only lasts a year!

According to scientists, those who say that true love lasts a lifetime have got it completely wrong and in fact it only lasts a year.

2 Dec 2005

Spinal cord cells to be repaired by using nose cells

Plans are afoot next year for British surgeons to attempt to make the first repairs of spinal cord nerves using a revolutionary new stem cell technique.

30 Nov 2005

Chronic stress induces rapid occlusion of angioplasty

Chronic stress can induce rapid blocking of arteries after a balloon angioplasty procedure, according to research performed in animal studies at Georgetown University Medical Center. Blocked coronary arteries after angioplasty affect 41 percent of patients who undergo the procedure and can lead to death.

28 Nov 2005

Exercise in moderation best for the brain

Exercise is good for your physical health. We have known this for a long time. We also know that physical activity is good for the brain and alleviates depression and stress.

28 Nov 2005

A sign of the times - fat bums mean longer needles for that jab

It has to be a sign of the times, according to researchers fatter backsides are causing many drug injections to miss their mark, and are requiring longer needles to reach buttock muscle.

28 Nov 2005

Chemical found in plants helps prevent lung cancer

According to the results of an animal study, it is suggested that treatment with a chemical found in various plants, may help prevent lung cancer caused by cigarette smoking.

28 Nov 2005

MGH study finds first function for, promising flexibility in adult-born nerve cells

New brain cells that develop in the olfactory system of adult mice appear to play a role in the brain different from that of older neurons.

28 Nov 2005

GRK2 protein - potential drug target for heart failure

A protein that plays an important regulatory role in heart failure in the heart also exerts powerful effects on the adrenal gland, Jefferson Medical College researchers have found. The protein, GRK2, is a potential drug target for heart failure.

28 Nov 2005

Epidural versus non-epidural or no analgesia in labour

Women who receive epidurals during labor report less pain than those who choose opiates or natural childbirth, according to a systematic review of evidence.

28 Nov 2005

Updated guidelines for diagnosing multiple sclerosis

An international panel of neurologists has updated the current guidelines for diagnosing multiple sclerosis (MS), strengthening the role of magnetic resonance imaging (MRI).

26 Nov 2005

Compound from Salinispora (marine bacteria) kills blood cancer cells

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

21 Nov 2005

Critical role of p53 gene

Fruit flies can live significantly longer, and remain healthy, when activity of the fly version of the tumor-suppressing protein p53 is reduced in nerve cells.

21 Nov 2005

Nanotechnology and biochemistry provide new way to study T cell signaling

Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley, combining nanotechnology with biochemistry, have created unique synthetic membranes that, for the first time ever, enable them to directly control signaling activity in living T cells from the immune system. Already their experiments have yielded surprising results.

21 Nov 2005

Lowering calorie intake may help Parkinson's disease

A new Oregon Health & Science University and Portland Veterans Affairs Medical Center study suggests that early-stage Parkinson's disease patients who lower their calorie intake may boost levels of an essential brain chemical lost from the neurodegenerative disorder.

20 Nov 2005