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'Brown fat cells' hold clues for possible obesity treatments

Joslin Diabetes Center scientists have discovered a group of genes that govern the genesis of calorie-burning fat cells. This discovery may lead to novel ways to treat obesity in humans.

26 May 2005

Researchers have succeeded in mapping the unique patterns of neural activity produced by a wide range of odors

Revealing these distinct - but often overlapping - patterns of neural activity represents a significant step in understanding how the brain translates complex signals from odorant receptors in the nose into odor perception in the brain, the researchers said.

26 May 2005

Protein TRPA1 essential for hearing also vital for pain perception

The same protein that "translates" sound into nerve signals to the brain and enables individuals to hear is also required for pain perception, researchers from Northwestern University Feinberg School of Medicine have found.

25 May 2005

Scientists watch agents of brain-wasting diseases invade and move within brain cells

Scientists for the first time have watched agents of brain-wasting diseases, called transmissible spongiform encephalopathies (TSE), as they invade a nerve cell and then travel along wire-like circuits to points of contact with other cells.

25 May 2005

Medical Research Council funds research to look at cannabis based medicines in multiple sclerosis treatment

A trial to determine whether cannabis-based medicines can reduce disability in patients with multiple sclerosis (MS) has been funded by the Medical Research Council (MRC).

24 May 2005

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, UCSF medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

23 May 2005

Gene keeps neural cells on correct developmental path

23 May 2005

Investigational device-based therapies will lead to entirely new treatment options for chronic depression sufferers

Researchers said that developing brain stimulation techniques such as transcranial magnetic stimulation (TMS), vagal nerve stimulation and deep brain stimulation are emerging as significant treatment options for the millions of patients "poorly served" by existing therapies.

23 May 2005

New insight into the machinery cells use to internalize cell surface receptors

Using state of the art imaging technology a team from Yale School of Medicine has glimpsed one of the cell's most important 'nano-machines' in action. The work, performed in collaboration with English and French scientists, provides new insight into the machinery cells use to internalize cell surface receptors.

22 May 2005

Gene keeps neural cells on correct developmental path

Embryonic stem cells with identical genomes grow into distinctive tissues, such as heart, bone, and brain. At one time, scientists believed the differences among cell types arose from various sets of genes switched on inside developing cells. Then, studies showed that adult neurons uniquely lack a protein that permanently turns off neuronal genes in the rest of the body's cells.

20 May 2005

Dextromethorphan temporarily reduces the intensity of fibromyalgia

Dextromethorphan, an over-the-counter medication that silences coughs, may help fibromyalgia patients quiet over-reacting nerves that amplify ordinary touches into agony.

20 May 2005

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, University of California, San Francisco (UCSF) medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

20 May 2005

Deadly baby disease can be arrested with early treatment

U.S. scientists have found that transplanting umbilical cord blood to seemingly healthy infants before they develop signs of Krabbe's disease can dramatically prolong the lives of children with the deadly genetic condition.

19 May 2005

Researchers prevent post-traumatic brain damage using experimental drug

In animal studies, researchers from Georgetown University Medical Center have shown how traumatic brain injury leads to loss of brain function - and found that an experimental drug can stop the damage and promote recovery.

18 May 2005

Unrestrained retina too much of a good thing

When primitive nerve cells begin forming an eye in the mouse embryo, they are programmed to build a retina. But the ability to see depends upon connecting the retina to the brain via the optic nerve. Unless these embryonic cells are given the right cue at the right time, they mistakenly form a huge eye that consists entirely of retina and lacks the optic nerve.

18 May 2005

Engineers have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes

In the study led by Dr. Christine Schmidt, the researchers identified a piece of protein from among a billion candidates that could perform the unusual feat of attaching to polypyrrole, a synthetic polymer (plastic) that conducts electricity and has shown promise in biomedical applications.

17 May 2005

Changes in certain brain receptors can affect seizures and anxiety during the menstrual cycle

A new UCLA study shows that changes in certain brain receptors can affect seizures and anxiety during the menstrual cycle--findings that could lead to novel therapies for premenstrual dysphoric disorder (PMDD, formerly known as PMS) and other central nervous system symptoms associated with the menstrual cycle.

16 May 2005

Genetic biomarker that may improve quality of life during treatment for colorectal cancer

A Mayo Clinic-led study has revealed a genetic biomarker that can predict which patients are most likely to experience unwanted side effects from one of the most commonly used and highly effective chemotherapy regimens designed to treat colorectal cancer.

16 May 2005

Surgical technique provides the first permanent solution to treating vocal-cord spasms

The first large, long-term study of patients who had surgery to control vocal-cord spasms showed excellent results in the majority of cases, reports new UCLA research presented May 14 at the 126th Annual Meeting of the American Laryngological Association.

15 May 2005

Broader range of treatments for excessive sweating disorder, Mayo Clinic Proceedings says

The often embarrassing, excessive sweating disorder, hyperhidrosis, and its treatment options are gaining greater attention from physicians. This is improving the efficacy of treatment and minimizing its adverse effects, Mayo Clinic authors write in the May issue of Mayo Clinic Proceedings.

11 May 2005

Nerve News and Research

'Brown fat cells' hold clues for possible obesity treatments

Researchers have succeeded in mapping the unique patterns of neural activity produced by a wide range of odors

Protein TRPA1 essential for hearing also vital for pain perception

Scientists watch agents of brain-wasting diseases invade and move within brain cells

Medical Research Council funds research to look at cannabis based medicines in multiple sclerosis treatment

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Gene keeps neural cells on correct developmental path

Investigational device-based therapies will lead to entirely new treatment options for chronic depression sufferers

New insight into the machinery cells use to internalize cell surface receptors

Gene keeps neural cells on correct developmental path

Dextromethorphan temporarily reduces the intensity of fibromyalgia

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Deadly baby disease can be arrested with early treatment

Researchers prevent post-traumatic brain damage using experimental drug

Unrestrained retina too much of a good thing

Engineers have found a way to modify a plastic to anchor molecules that promote nerve regeneration, blood vessel growth or other biological processes

Changes in certain brain receptors can affect seizures and anxiety during the menstrual cycle

Genetic biomarker that may improve quality of life during treatment for colorectal cancer

Surgical technique provides the first permanent solution to treating vocal-cord spasms

Broader range of treatments for excessive sweating disorder, Mayo Clinic Proceedings says

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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