Neurodegeneration News and Research

RSS

Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Decline in specific protein levels linked to Alzheimer’s disease, not buildup of amyloid plaques

New research from the University of Cincinnati bolsters a hypothesis that Alzheimer's disease is caused by a decline in levels of a specific protein, contrary to a prevailing theory that has been recently called into question.

5 Oct 2022

Study reveals a promising therapeutic target for spinocerebellar ataxia type 14

Spinocerebellar ataxias are a group of neurodegenerative diseases characterized by the degeneration of Purkinje cells, a major class of neurons in the cerebellum.

3 Oct 2022

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Researchers explored the in vivo efficacy of SARS-CoV-2-encoded proteins against neuromuscular degeneration associated with ribosome stalling.

3 Oct 2022

Treatment for neurological diseases often no longer effective enough in the later stages

Neurological diseases often begin with an inflammatory process and the degradation of the so-called myelin layer, which surrounds the nerve fibers (axons) like a protective insulating layer.

28 Sep 2022

Singapore researchers identify protein that transports degraded membrane lipids out of lysosomes

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown factories of cells.

27 Sep 2022

SARS-CoV-2 generates amyloid in cerebral spinal fluid

In a recent study posted to the bioRxiv* preprint server, an international team of researchers demonstrated amyloid aggregation due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human cerebrospinal fluid (CSF).

20 Sep 2022

Discovery could resolve one of the mysteries of Parkinson's disease

Aggregates of the protein alpha-synuclein spread in the brains of people with Parkinson's disease through a cellular waste-ejection process, suggests a new study led by Weill Cornell Medicine researchers.

20 Sep 2022

Aerobic exercise training shows potential to restore function in individuals with thalamic atrophy

Thalamic atrophy needs to be considered in clinical studies of the functional abilities of individuals with multiple sclerosis, according to findings reported by a team of experts.

16 Sep 2022

Nutritional approaches targeting gut microbiome could improve brain disorders

A new review published in the Clinical Nutrition and Metabolic Care journal focused on studies that utilized the dietary gut microbiota–target interventions to improve mental health conditions. It also discussed some suggestions for developing more robust and informative interventions for diet–microbiome studies.

15 Sep 2022

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

A new paper discusses the hope held out by recent results on a compound called irisin, a short protein secreted by skeletal muscle that produces some exercise-related effects on the brain.

15 Sep 2022

Age-related changes in microbiome composition affects brain macrophages

Scientists review the impact of age-related gut microbiome composition on age-associated diseases caused by dysfunctional macrophages within the brain.

13 Sep 2022

Exercise hormone reduces protein levels linked to Parkinson's disease

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice.

12 Sep 2022

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

Neurodegeneration News and Research

Further Reading

Decline in specific protein levels linked to Alzheimer’s disease, not buildup of amyloid plaques

Study reveals a promising therapeutic target for spinocerebellar ataxia type 14

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Treatment for neurological diseases often no longer effective enough in the later stages

Singapore researchers identify protein that transports degraded membrane lipids out of lysosomes

SARS-CoV-2 generates amyloid in cerebral spinal fluid

Discovery could resolve one of the mysteries of Parkinson's disease

Aerobic exercise training shows potential to restore function in individuals with thalamic atrophy

Nutritional approaches targeting gut microbiome could improve brain disorders

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

Age-related changes in microbiome composition affects brain macrophages

Exercise hormone reduces protein levels linked to Parkinson's disease

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

New research project investigates molecular mechanisms underlying NeuroCOVID

New gene therapy approach could help prevent blindness in children with Leber congenital amaurosis

The role of nasal microbiome in Parkinson's disease

Exposure to blue light may accelerate aging

The currently available evidence on viral-induced parkinsonism

EPFL scientists uncover key mechanisms underlying the formation of protein tangles in the brain

Penn State receives $1.6 million grant to study the link between COVID-19 and cognitive decline

Aneuro: A Year of Neuroscience in Review eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News