Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Retinal measurements associated with Parkinson’s disease duration

The inner retinal layers in the eyes of patients with Parkinson’s disease are thinner than those of healthy people’s eyes, except for the inner nuclear layer, which is thicker, show the results of a prospective study involving the latest optical coherence tomography methods.

1 May 2014

Genzyme, Cleveland Clinic partner to develop new therapeutic approaches for MS treatment

Genzyme, a Sanofi company, announced today the formation of a research collaboration with Cleveland Clinic focused on developing new therapeutic approaches to the treatment of MS.

30 Apr 2014

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

A study of older adults at increased risk for Alzheimer's disease shows that moderate physical activity may protect brain health and stave off shrinkage of the hippocampus- the brain region responsible for memory and spatial orientation that is attacked first in Alzheimer's disease.

25 Apr 2014

Sleep disorder is the best current predictor of brain diseases, say U of T researchers

Researchers at the University of Toronto say a sleep disorder that causes people to act out their dreams is the best current predictor of brain diseases like Parkinson's and Alzheimer's.

22 Apr 2014

New mouse model breakthrough for Alzheimer's disease research

Alzheimer's disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. In Japan, the burden of the disease in 2050 is estimated to be a half a trillion US dollars, a figure equivalent to the government's annual revenues.

15 Apr 2014

Scientists discover potential cause of Parkinson’s disease

Researchers have discovered a process that appears to explain how a well known enzyme mutation triggers the neural deterioration seen in Parkinson’s disease.

10 Apr 2014

New discovery opens door to development of new treatments that stop progression of Parkinson's disease

A research led by the Research Institute Vall d'Hebron (VHIR), in which the University of Valencia participated, has shown that pathological forms of the α-synuclein protein present in deceased patients with Parkinson's disease are able to initiate and spread in mice and primates the neurodegenerative process that typifies this disease.

10 Apr 2014

Vibrational spectroscopy opens up new ways to diagnose chronic diseases

In today’s ageing population, resulting in a rising prevalence of chronic diseases such as neurodegeneration, the need for simple, non-invasive methods to diagnose or screen for important medical conditions becomes more and more relevant. Objective and cost-effective approaches capable of diagnosing early-stage disease in point-of-care clinical settings are necessary to facilitate the personalising of therapies to prevent or slow down pathology development.

10 Apr 2014

New lab at the Nencki Institute conducts research on neurodegenerative diseases

The Laboratory of Preclinical Studies of Higher Standard, the newest lab of the Neurobiology Center at the Nencki Institute in Warsaw, Poland, will conduct basic research aimed to explain molecular mechanisms responsible for neurodegenerative diseases.

9 Apr 2014

Study explores relationship between genetics and lifestyle in development of AD

A global study involving more than one million people worldwide will explore the relationship between genetics and lifestyle in the development of Alzheimer's disease.

4 Apr 2014

Sanford-Burnham to present new cancer research data at AACR 2014

Sanford-Burnham Medical Research Institute will present a wide range of new research data at the annual American Association for Cancer Research Meeting in San Diego starting Saturday, April 5, at the San Diego Convention Center. The presentations will cover a variety of topics including breast, melanoma, and prostate cancer, as well as novel methods of delivering drugs to tumors.

4 Apr 2014

Stowers team reports genome-wide analysis of genes that drive cell division in multicellular organism

In textbooks, the grand-finale of cell division is the tug-of-war fought inside dividing cells as duplicated pairs of chromosomes get dragged in opposite directions into daughter cells.

3 Apr 2014

Study highlights benefits of using multiple injections to treat Sanfilippo syndrome type III B

New insight has been gained into treating an inherited disorder that creates serious neurological and behavioral disabilities in children and usually leads to death in the teen years.

28 Mar 2014

Retrophin acquires Manchester Pharmaceuticals

Retrophin, Inc. today announced the completion of the previously announced acquisition of Manchester Pharmaceuticals LLC for a total of $62.5 million, including an upfront payment of $29.5 million, plus other payments based on product sales.

27 Mar 2014

Initial stage of autophagy does not affect components of beclin 1 complex

Alteration of the autophagic process is involved in neurodegeneration. The beclin 1 complex is shown to play a key role in the initial stage of autophagy.

27 Mar 2014

Cogstate's cognition test to play key role in A4 trial for Alzheimer’s disease

Cognition testing technology developed by Cogstate will be used to track the neurological health of elderly people involved in the multinational Phase III clinical trial of a promising new Alzheimer’s disease (AD) drug.

26 Mar 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died.

26 Mar 2014

Researchers identify new player in onset and progression of heart failure

A team of cardiovascular researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai, Sanford-Burnham Medical Research Institute, and University of California, San Diego have identified a small, but powerful, new player in the onset and progression of heart failure.

13 Mar 2014

Inherited Alzheimer's neuronal damage begins 10 to 20 years before symptoms appear

In a paper published in the prestigious journal Science Translational Medicine, Professor Colin Masters from the Florey Institute of Neuroscience and Mental Health and University of Melbourne - and colleagues in the UK and US - have found rapid neuronal damage begins 10 to 20 years before symptoms appear.

10 Mar 2014

Scientists reveal how a genetic code variation results in devastating brain diseases

New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die.

6 Mar 2014

Neurodegeneration News and Research

Further Reading

Retinal measurements associated with Parkinson’s disease duration

Genzyme, Cleveland Clinic partner to develop new therapeutic approaches for MS treatment

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

Sleep disorder is the best current predictor of brain diseases, say U of T researchers

New mouse model breakthrough for Alzheimer's disease research

Scientists discover potential cause of Parkinson’s disease

New discovery opens door to development of new treatments that stop progression of Parkinson's disease

Vibrational spectroscopy opens up new ways to diagnose chronic diseases

New lab at the Nencki Institute conducts research on neurodegenerative diseases

Study explores relationship between genetics and lifestyle in development of AD

Sanford-Burnham to present new cancer research data at AACR 2014

Stowers team reports genome-wide analysis of genes that drive cell division in multicellular organism

Study highlights benefits of using multiple injections to treat Sanfilippo syndrome type III B

Retrophin acquires Manchester Pharmaceuticals

Initial stage of autophagy does not affect components of beclin 1 complex

Cogstate's cognition test to play key role in A4 trial for Alzheimer’s disease

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

Researchers identify new player in onset and progression of heart failure

Inherited Alzheimer's neuronal damage begins 10 to 20 years before symptoms appear

Scientists reveal how a genetic code variation results in devastating brain diseases

Aneuro: A Year of Neuroscience in Review eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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