Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Epstein-Barr virus may be associated with progression of multiple sclerosis

Epstein-Barr virus (EBV), the pathogen that causes mononucleosis, appears to play a role in the neurodegeneration that occurs in persons with multiple sclerosis, researchers at the University at Buffalo and the University of Trieste, Italy, have shown.

2 Mar 2009

Two compounds show great promise for cerebral palsy

Two compounds developed by Northwestern University chemists have been shown to be effective in pre-clinical trials in protecting against cerebral palsy, a condition caused by neurodegeneration that affects body movement and muscle coordination.

25 Feb 2009

Could a hereditary illness ever spread by contamination?

Researchers at the CNRS Laboratoire d'enzymologie et biochimie structurales, studying Huntington's disease in collaboration with Professor Ron Kopito's team at Stanford University, have shown that the normal form of huntingtin protein can acquire an abnormal form without any modification of its genetic code.

10 Feb 2009

Rare amino acid helps establish how proteins evolve

Three billion years ago, a "new" amino acid was added to the alphabet of 20 that commonly make up proteins in organisms today.

29 Jan 2009

Researchers identify compound that frees trapped cholesterol

Researchers at UT Southwestern Medical Center have identified in mice a compound that liberates cholesterol that has inappropriately accumulated to excessive levels inside cells.

27 Jan 2009

Scientists discover a compound that gets rid of excess cholesterol

New research by scientists in the United States carried out in mice has revealed a compound that releases excessive cholesterol accumulated inside cells.

27 Jan 2009

Drinking apple juice may delay onset of Alzheimer's disease

A growing body of evidence demonstrates that we can take steps to delay age-related cognitive decline, including in some cases that which accompanies Alzheimer's disease, according to a study published in the January 2009 issue of the Journal of Alzheimer's Disease.

23 Jan 2009

Lou Gehrig's disease in humans has genetic links to degenerative myelopathy in dogs

An incurable, paralyzing disease in humans is now genetically linked to a similar disease in dogs.

21 Jan 2009

Study shows how defective DNA repair triggers 2 neurological diseases

Scientists at St. Jude Children's Research Hospital have teased apart the biological details distinguishing two related neurological diseases-ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS).

15 Jan 2009

Relapses more frequent in patients diagnosed with pediatric-onset multiple sclerosis

Patients who develop multiple sclerosis before age 18 appear to experience more relapses of symptoms than those diagnosed with the disease as adults, according to a report in the January issue of Archives of Neurology.

12 Jan 2009

Discovery of mechanism that may explain Parkinson's and other neurological disorders

Studying just eight families worldwide, the international team of researchers have discovered a genetic defect that results in profound depression and parkinsonism in a disorder known as Perry syndrome.

12 Jan 2009

Innovative brain-scan technology helps visualize brain aging before symptoms appear

UCLA scientists have used innovative brain-scan technology developed at UCLA, along with patient-specific information on Alzheimer's disease risk, to help diagnose brain aging, often before symptoms appear.

6 Jan 2009

Alzheimer's researcher explores the variety of animal models now being used in research

Very few species spontaneously develop the cognitive, behavioral and neuropathological symptoms of Alzheimer's disease (AD), yet AD research must progress at a more rapid pace than the rate of human aging.

15 Dec 2008

Scientists create infectious prion disease in mouse model

A worldwide group of scientists has created an infectious prion disease in a mouse model, in a step that may help unravel the mystery of this progressive disease that affects the nervous system in humans and animals.

8 Dec 2008

Nitric oxide can change computational ability of the brain

Research from the Medical Research Council (MRC) Toxicology Unit at the University of Leicester shows that nitric oxide (NO) can change the computational ability of the brain.

26 Nov 2008

Fruit flies provide new insights into a brain-damaging disease mucolipidosis type IV

Johns Hopkins researchers have used fruit flies to gain new insights into a brain-damaging disorder afflicting children.

26 Nov 2008

Researchers reduce production of alpha-synuclein in the brain - offers hope for Parkinson's disease

Mayo Clinic researchers have developed a method to reduce the production of alpha-synuclein in the brain.

17 Nov 2008

Researchers uncover beneficial mechanism of the helpful "Dr. Jekyll" side of the Cdk5 protein

Researchers at UT Southwestern Medical Center have uncovered new insights into the "Dr. Jekyll and Mr. Hyde" nature of a protein that stimulates stem-cell maturation in the brain but, paradoxically, can also lead to nerve-cell damage.

12 Nov 2008

Protein can nurture or devastate brain cells, depending on its 'friends,' UT Southwestern researchers find

11 Nov 2008

Newborn neurons in the adult brain can settle in the wrong neighborhood

In a study that could have significant consequences for neural tissue transplantation strategies, researchers at the Salk Institute for Biological Studies report that inactivating a specific gene in adult neural stem cells makes nerve cells emerging from those precursors form connections in the wrong part of the adult brain.