Neurodegenerative Disease News and Research

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Women's cognitive decline associated with interrupted or fitful sleep

Women who experienced cognitive decline over a 13 to 15 year period after age 65 were more likely to sleep poorly than women whose cognition did not decline, according to a study led by researchers at the San Francisco VA Medical Center (SFVAMC).

17 Jul 2007

New criteria for probable Alzheimer's disease

An international group of Alzheimer's disease (AD) experts have proposed new criteria for the reasearch diagnosis of the condition, as they argue the existing criteria are out of date due to unprecedented growth of scientific knowledge in the field. The proposal is put forward in a Position Paper published early Online and in the August edition of The Lancet Neurology.

9 Jul 2007

New drug target for the treatment of Parkinson's disease

Researchers at the MassGeneral Institute for Neurodegenerative Disease (MGH-MIND) have identified a potential new drug target for the treatment of Parkinson's disease and possibly for other degenerative neurological disorders.

23 Jun 2007

PINK1 protects from Parkinson's

Parkinson disease (PD) is a common neurodegenerative disease characterized by the selective loss of midbrain dopaminergic neurons.

19 Jun 2007

Scientists link cell's protein recycling systems

Many age-related neurological diseases are associated with defective proteins accumulating in nerve cells, suggesting that the cell's normal disposal mechanisms are not operating correctly.

17 Jun 2007

Early results from Alzheimer's neuroimaging studies could speed research

Disease researchers may be able to reduce the time and expense associated with clinical trials, according to early results from the Alzheimer's Disease Neuroimaging Initiative (ADNI), a public-private research partnership organized by the National Institutes of Health.

14 Jun 2007

Moderate strengthening exercises may slow progression of Lou Gehrig's disease

Moderate strengthening exercises may help people with early stage ALS maintain function and quality of life longer, according to a study published in the June 5, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology.

5 Jun 2007

Natural chemical with memory-enhancing effects

A natural compound found in blueberries, tea, grapes, and cocoa enhances memory in mice, according to newly published research.

30 May 2007

CoQ10 may not provide benefits to individuals with Parkinson's disease

These findings contradict results from earlier studies involving a high purity CoQ10 supplement, Vitaline(R) CoQ10. Richard M. Delany, M.D., FACC, and founder of Personalized Preventive Medicine, finds that a closer review of this latest study design reveals important weaknesses, including the use of a short study duration (3 months) and a low daily dosage (300 mg), and failure to use the clinically proven CoQ10 product, Vitaline CoQ10.

22 May 2007

Link between extreme sleep disorder and onset of parkinsonism or dementia

Mayo Clinic researchers and a group of international collaborators have discovered a correlation between an extreme form of sleep disorder and eventual onset of parkinsonism or dementia.

17 May 2007

Researchers develop first images of physical changes in brain cells thought to underlie memory

University of California, Irvine researchers have developed the first images of the physical changes in brain cells thought to underlie memory, a discovery that is already uncovering clues about memory loss linked to cognitive disorders.

17 May 2007

Scientists find new proteins involved in Huntington's disease

Researchers in the United States have identified more than 200 new proteins that are involved in Huntington's disease.

14 May 2007

Evidence that dementia can be successfully stalled

A University of Sydney academic is part of a team whose research could profoundly change the way we look at and treat dementia.

11 May 2007

Identification of 200 new proteins that interact with the mutated protein that causes Huntington's disease

The identification of more than 200 new proteins that interact with the mutated protein that causes Huntington's disease opens the door to developing treatments for the fatal neurodegenerative disorder, said a Baylor College of Medicine researcher who took part in the work that appears online today in the journal Public Library of Science Genetics.

11 May 2007

New compounds promising candidates for neurodegenerative disease drug development

Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.

8 May 2007

Current approach to drug discovery for Lou Gehrig's disease be re-examined

Most research on Lou Gehrig's disease therapeutics has been based on the assumption that its two forms (sporadic and hereditary) are similar in their underlying cause.

8 May 2007

Avicena files composition of matter patent application for treatment of Huntington's disease

Avicena Group has announced day that it has filed a composition of matter patent application with the United States Patent and Trademark Office (USPTO) to cover potential treatments for Huntington's disease, a fatal neurodegenerative disease.

1 May 2007

Environment rich in sensory stimuli restores memory in mice with neurodegeneration

Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli, according to new studies by Howard Hughes Medical Institute researchers.

30 Apr 2007

Avicena files composition of matter patent application for treatment of Parkinson's disease

Avicena Group, Inc. has announced that it has filed a composition of matter patent application with the United States Patent and Trademark Office to cover potential treatments for Parkinson's disease, a progressive neurodegenerative disease.

27 Apr 2007