Neurodegenerative Diseases News and Research

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Novogen receives funding support to commence studies in muscular dystrophy

The Australian biotechnology company, Novogen Limited today announced receipt of funding from the FSHD Global Research Foundation as part of the Company’s efforts to find effective treatments for a range of musculo-degenerative diseases including facioscapulohumeral dystrophy (FSHD).

11 Aug 2014

Infectious prion protein is marker for variant Creutzfeldt-Jakob disease

The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease - linked to the consumption of infected cattle meat - has been detected in the urine of patients with the disease by researchers at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

8 Aug 2014

Penn physiologist receives Javits Neuroscience Investigator Award from NIH

Erika Holzbaur, PhD, a professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania, has received the Javits Neuroscience Investigator Award from the National Institutes of Health.

6 Aug 2014

Neuroscientists shed new light on how the brain works

Neuroscientists in Bonn and Heidelberg have succeeded in providing new insights into how the brain works. Researchers at the DZNE and the German Cancer Research Center analyzed tissue samples from mice to identify how two specific proteins, ‘CKAMP44’ and ‘TARP Gamma-8’, act upon the brain’s memory center.

26 Jul 2014

CanTx, Novogen name two key CMOs to manufacture clinical batches of anti-cancer drug Cantrixil

Oncology drug developer, CanTx Inc., and its parent company, Novogen Ltd., today announced that they have named two key contract manufacturing organizations (CMOs) to produce clinical batches of the experimental anti-cancer drug, Cantrixil.

26 Jul 2014

BU researchers find possible way to prevent Alzheimer's disease

Boston University School of Medicine researchers may have found a way to delay or even prevent Alzheimer's disease (AD). They discovered that pre-treatment of neurons with the anti-aging protein Klotho can prevent neuron death in the presence of the toxic amyloid protein and glutamate.

25 Jul 2014

Autophagy prevents accumulation of toxic proteins associated with type 2 diabetes

People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin-producing pancreatic beta cells.

25 Jul 2014

Study: Dementia carers may require more support with medication management

Family carers of people with dementia may need more support with medication management, according to a recent study.

25 Jul 2014

Study reveals novel epilepsy pathway linked to neurodegenerative diseases

A recent scientific discovery showed that mutations in prickle genes cause epilepsy, which in humans is a brain disorder characterized by repeated seizures over time. However, the mechanism responsible for generating prickle-associated seizures was unknown.

23 Jul 2014

Researchers identify molecular mechanisms of cognitive decline using high-throughput proteomics

From telephone numbers to foreign vocabulary, our brains hold a seemingly endless supply of information. However, as we are getting older, our ability to learn and remember new things declines.

22 Jul 2014

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

A type of immune cell widely believed to exacerbate chronic adult brain diseases, such as Alzheimer's disease and multiple sclerosis (MS), can actually protect the brain from traumatic brain injury (TBI) and may slow the progression of neurodegenerative diseases, according to Cleveland Clinic research published today in the online journal Nature Communications.

22 Jul 2014

Researchers identify group of cells in brain that plays important role in Down syndrome

Researchers from UC Davis School of Medicine and Shriners Hospitals for Children - Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome.

21 Jul 2014

Deadly neurodegenerative disease treated in worms gives hope for humans

An untreatable and deadly neurodegenerative disease has been modelled and treated in worms by University of Liverpool researchers, suggesting a cure could be found for humans.

17 Jul 2014

Sleep problems in PD patients can worsen in later stages of disease

Up to 70% of Parkinson's disease (PD) patients experience sleep problems that negatively impact their quality of life.

11 Jul 2014

New study sheds light on role of RPM-1 protein in neuron development

In a new study, scientists from the Florida campus of The Scripps Research Institute have shed new light on these complex processes, showing that a particular protein plays a far more sophisticated role in neuron development than previously thought.

11 Jul 2014

Clinicians launches ACEmobile app to support assessment of dementia

A team of clinicians from Plymouth, UK, and Sydney, Australia, have today (Wednesday 9th July 2014 UK, Thursday 10th July Australia) launched ACEmobile - a free-to-use app to support the assessment of dementia, worldwide.

8 Jul 2014

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a chemical "switch" that controls both the generation of new neurons from neural stem cells and the survival of existing nerve cells in the brain.

4 Jul 2014

Researchers identify pathogenic mechanism common to several neurodegenerative diseases

An international team of researchers identified a pathogenic mechanism that is common to several neurodegenerative diseases. The findings suggest that it may be possible to slow the progression of dementia even after the onset of symptoms.

4 Jul 2014

Persons with reduced levels of TREM2 protein at greater risk for neurodegenerative diseases

Persons with reduced levels of the TREM2 protein could be at greater risk of developing neurodegenerative diseases such as Alzheimer's disease or frontotemporal dementia, according to an international study which included the participation of the Universitat Autònoma de Barcelona and the Sant Pau Biomedical Research Institute.

3 Jul 2014

Short sleep linked to cognitive decline in older adults

Researchers at Duke-NUS Graduate Medical School Singapore (Duke-NUS) have found evidence that the less older adults sleep, the faster their brains age.

1 Jul 2014

Neurodegenerative Diseases News and Research

Novogen receives funding support to commence studies in muscular dystrophy

Infectious prion protein is marker for variant Creutzfeldt-Jakob disease

Penn physiologist receives Javits Neuroscience Investigator Award from NIH

Neuroscientists shed new light on how the brain works

CanTx, Novogen name two key CMOs to manufacture clinical batches of anti-cancer drug Cantrixil

BU researchers find possible way to prevent Alzheimer's disease

Autophagy prevents accumulation of toxic proteins associated with type 2 diabetes

Study: Dementia carers may require more support with medication management

Study reveals novel epilepsy pathway linked to neurodegenerative diseases

Researchers identify molecular mechanisms of cognitive decline using high-throughput proteomics

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

Researchers identify group of cells in brain that plays important role in Down syndrome

Deadly neurodegenerative disease treated in worms gives hope for humans

Sleep problems in PD patients can worsen in later stages of disease

New study sheds light on role of RPM-1 protein in neuron development

Clinicians launches ACEmobile app to support assessment of dementia

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

Researchers identify pathogenic mechanism common to several neurodegenerative diseases

Persons with reduced levels of TREM2 protein at greater risk for neurodegenerative diseases

Short sleep linked to cognitive decline in older adults

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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