Neurodegenerative Diseases News and Research

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Insights and new directions in basic, clinical research into neurodegenerative diseases

A special supplement to the Journal of Alzheimer's Disease, published by IOS Press, presents insights and new directions in both basic and clinical research into neurodegenerative diseases.

28 Sep 2023

How do different polyphenol-rich foods impact chronic diseases?

The potential of phytochemicals in promoting a healthy human diet to combat chronic disease.

27 Sep 2023

Research uncovers a link between antiviral drug for COVID-19 and SARS-CoV-2 mutations

Researchers at the Francis Crick Institute, the University of Cambridge, Imperial College London, the University of Liverpool, the University of Cape Town and UKHSA have uncovered a link between an antiviral drug for COVID-19 infections called molnupiravir and a pattern of mutations in the SARS-CoV-2 virus.

25 Sep 2023

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Recent research demonstrates that protein phase separation (PPS) is widely present in cells and drives a variety of important biological functions.

25 Sep 2023

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases.

25 Sep 2023

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Researchers compared two commercially available blood tests based on the biomarker p-tau217 for diagnosing Alzheimer's disease in 294 patients. Both tests demonstrated robust diagnostic capabilities, strongly correlating with established Alzheimer's biomarkers from PET scans.

24 Sep 2023

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Researchers at Washington University School of Medicine identify a key step in the development of harmful tau tangles, offering a potential target for preventing brain damage in diseases like Alzheimer's. The study highlights the role of long noncoding RNAs, particularly SNHG8, in stress granule formation and tau aggregation, opening new avenues for treatment.

22 Sep 2023

New study maps the spread of brain changes in psychosis

Psychoses like schizophrenia cost billions of dollars annually and derail the lives of people struggling with the disease.

20 Sep 2023

Is maple syrup the ultimate natural sweetener? Researchers say it's more than just tasty!

Scientists explore the myriad benefits of maple syrup, revealing its nutritional, pharmacological, and sensory advantages over traditional sweeteners. From antioxidant and anti-inflammatory properties to controlling blood sugar and even potential anticancer effects, maple syrup is more than just a tasty topping.

14 Sep 2023

Researchers discover backup protein quality control mechanism

Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.

14 Sep 2023

Specialized gut immune cells could be new biomarker for IBD progression

Researchers at the Francis Crick Institute, King's College London and Guy's and St Thomas' NHS Foundation Trust have characterised a specialised type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.

14 Sep 2023

New MRI technology promises to revolutionize understanding of iron homeostasis in the brain

Research team led by Shir Filo and Prof. Aviv Mezer of the Safra Center for Brain Science at the Hebrew University of Jerusalem (ELSC) and Dr. Tal Shahar currently, Director of the Neurosurgical Oncology Unit at the Neurosurgery Department, Tel Aviv Sourasky Medical Center, have unveiled a groundbreaking magnetic resonance imaging (MRI) technology that promises to revolutionize our understanding of iron homeostasis in the human brain.

12 Sep 2023

Study reports an increase in incidence of islet autoimmunity after SARS-CoV-2 infection in young children

Type 1 diabetes is an autoimmune disease leading to an impaired glucose metabolism and requires life-long administration of insulin.

8 Sep 2023

Mount Sinai researchers identify the structure of a special red blood cell transporter

Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs.

8 Sep 2023

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.

8 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023

Neurodegenerative Diseases News and Research

Insights and new directions in basic, clinical research into neurodegenerative diseases

How do different polyphenol-rich foods impact chronic diseases?

Research uncovers a link between antiviral drug for COVID-19 and SARS-CoV-2 mutations

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

New study maps the spread of brain changes in psychosis

Is maple syrup the ultimate natural sweetener? Researchers say it's more than just tasty!

Researchers discover backup protein quality control mechanism

Specialized gut immune cells could be new biomarker for IBD progression

New MRI technology promises to revolutionize understanding of iron homeostasis in the brain

Study reports an increase in incidence of islet autoimmunity after SARS-CoV-2 infection in young children

Mount Sinai researchers identify the structure of a special red blood cell transporter

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Aligning Rhythms, Defying Alzheimer's: Intermittent Fasting's Role in Combating Alzheimer's Disease Neurodegeneration

Scientists discover new microglial population important for memory and learning

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

Microplastics found to bioaccumulate in every organ of mice

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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