Neurodegenerative Diseases News and Research

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AI model analyzes retinal images to detect early Alzheimer’s disease and cognitive decline

Researchers developed an AI-based deep learning model that uses retinal images to detect early-stage Alzheimer's disease and mild cognitive impairment with high accuracy, offering a noninvasive, cost-effective screening tool.

22 Oct 2024

New study reveals molecular mechanism in Alzheimer's disease

A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new molecular mechanism that affects RNA processing and alters the process of protein synthesis in the brains of Alzheimer's patients.

18 Oct 2024

New protein found to protect cells from age-related decline

McMaster University researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall.

18 Oct 2024

Study reveals how Alzheimer's may cause brain damage in two distinct phases

Alzheimer's disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

15 Oct 2024

Emory University researchers shift focus to neuroinflammation in Alzheimer's treatment

For decades, Alzheimer's research has focused on examining amyloid plaques in the brain and prescribing antibody therapeutics that remove the plaques to slow cognitive decline in patients.

15 Oct 2024

Study explores impact of active navigation and immersive environments on episodic memory

Just like a time machine, episodic memory enables us to travel to the past in our minds and relive personal experiences with full clarity, as if we were going through them all over again.

15 Oct 2024

A novel approach to understanding protein compartmentalization

In physics, a system composed of two substances can be modeled in accordance with classical mixture theory, which considers the fraction corresponding to each constituent and the interactions among constituents. Examples include the coexistence of high- and low-density phases in supercooled water and the coexistence of metal puddles in an insulating matrix in the Mott metal-insulator transition.

14 Oct 2024

Boost your heart, save your brain: How better heart health fights dementia

Research highlights the strong connection between heart and brain health, showing that improving cardiovascular health can help prevent cognitive decline and dementia. It underscores the shared biological mechanisms that link cardiac diseases to neurological impairment.

13 Oct 2024

New insights on protein degraders open doors to treatment for 'undruggable' diseases

Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called 'protein degraders' which can be deployed to combat what have previously been regarded as 'undruggable' diseases, including cancers and neurodegenerative diseases.

12 Oct 2024

Three common cardiovascular diseases linked to cognitive impairment and dementia risk

Three common cardiovascular diseases in adults-;heart failure, atrial fibrillation and coronary heart disease-;are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association published today in the Association's journal, Stroke.

10 Oct 2024

The role of geroscience in understanding Alzheimer’s Disease

For more than 30 years, researchers have identified and quantified genetic and lifestyle factors for Alzheimer's Disease (AD) and other dementias. Despite extensive research, the fundamental mechanisms behind these neurodegenerative diseases are still not fully understood, and effective management of AD is taking longer than expected.

10 Oct 2024

Pitt researchers validate comprehensive blood test for Alzheimer's biomarkers

University of Pittsburgh scientists independently validated a new blood test platform that can simultaneously measure more than a hundred biomarkers of Alzheimer's disease.

9 Oct 2024

Breakthrough study reveals Entropic Pulling mechanism of Hsp70 chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer.

8 Oct 2024

Smartphone data can reveal early dementia risks during real-world navigation

Researchers found that smartphone data from a wayfinding task can reveal cognitive decline patterns in older adults, especially those with subjective cognitive decline (SCD).

8 Oct 2024

GLP-1 drugs protect brain health by improving neurovascular function and reducing inflammation

Research highlights how GLP-1 receptor agonists may improve brain health by targeting the neurovascular unit, linking metabolic health to cognitive function. It suggests potential therapies for neurodegenerative diseases like Alzheimer's.

7 Oct 2024

Researchers uncover secret to regulating the body's internal clock

Scientists from Duke-NUS Medical School and the University of California, Santa Cruz, have discovered the secret to regulating our internal clock.

7 Oct 2024

International experts to gather for ALS symposium in Chicago

The 2024 Les Turner Symposium on ALS will be held on Monday, Nov. 4 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will assemble internationally-renowned ALS researchers, clinicians, advocates, and people living with ALS to discuss the latest research and perspectives on the disease.

3 Oct 2024

Researchers use smartphone data for early detection of Alzheimer's

Researchers from DZNE and Otto von Guericke University Magdeburg have identified individuals with increased risk for dementia using mobility data, recorded during a smartphone-based wayfinding task on the university campus.

3 Oct 2024

UNF professor secures NIH grant to investigate enzyme's role in muscle atrophy

A University of North Florida biology professor has been awarded a prestigious four-year National Institutes of Health (NIH) grant totaling over $720K to study the functional role of an enzyme called dual-specificity phosphatase 4 (Dusp4) in skeletal muscle atrophy.

3 Oct 2024

Researchers make breakthrough in Alzheimer's disease drug development

An international team of researchers led by Lancaster University have made a promising breakthrough in the development of drugs to treat Alzheimer's Disease.

3 Oct 2024