Neurodegenerative Diseases News and Research

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Expert in gene therapy joins The Children's Hospital of Philadelphia

Beverly L. Davidson, Ph.D., a nationally prominent expert in gene therapy, is joining The Children's Hospital of Philadelphia (CHOP) today.

2 Apr 2014

EMD Serono collaborates with Pfizer and Broad Institute

EMD Serono, a subsidiary of Merck KGaA, Darmstadt, Germany, today announced they have signed a research agreement with Pfizer Inc. and the Broad Institute in Cambridge, Massachusetts, U.S. The collaboration is focused on the genomic profiling of Systemic Lupus Erythematosus (SLE) and Lupus Nephritis (LN) patients.

1 Apr 2014

Aspartic acid in hippocampus may be biomarker for predicting occurrence of cognitive dysfunction

Postoperative cognitive dysfunction is the deterioration of cognitive performance after anesthesia and surgery, and manifests as impairments in short-term memory, concentration, language comprehension, and social integration skills.

31 Mar 2014

Biogen Idec's ALPROLIX receives FDA approval for hemophilia B treatment

Today Biogen Idec announced that the U.S. Food and Drug Administration has approved ALPROLIX [Coagulation Factor IX (Recombinant), Fc Fusion Protein], the first recombinant, DNA derived hemophilia B therapy with prolonged circulation in the body.

29 Mar 2014

Researchers review influence of lipid rafts on progression of Alzheimer's disease

Research over decades has implicated aberrant autophagy and lysosomal function as reliable markers and therapeutic targets for neurodegenerative diseases.

27 Mar 2014

Genable Technologies, Spark Therapeutics to advance novel therapy for rare form of retinitis pigmentosa

Spark Therapeutics and Genable Technologies announced today that they have entered into a collaboration agreement for Genable's lead therapeutic to treat rhodopsin-linked autosomal dominant retinitis pigmentosa (RHO adRP), GT038.

25 Mar 2014

Biogen Idec's ALPROLIX gets Health Canada approval for hemophilia B

Today Biogen Idec announced that Health Canada has approved ALPROLIX [Coagulation Factor IX (Recombinant), Fc Fusion Protein], for the control and prevention of bleeding episodes and routine prophylaxis in adults, and children aged 12 and older, with hemophilia B.

21 Mar 2014

New treatment could halt progression of dementia

Researchers at the University of Texas Medical Branch at Galveston have discovered a way to potentially halt the progression of dementia caused by accumulation of a protein known as tau.

21 Mar 2014

University of Chicago/ MBL announce first two recipients of Frank R. Lillie Research Innovation Awards

The University of Chicago and the Marine Biological Laboratory (MBL) today announced the first two recipients of the Frank R. Lillie Research Innovation Awards.

14 Mar 2014

Exosome Diagnostics closes Series B financing round with the raising of $27 million

Exosome Diagnostics today announced the initial close of its Series B financing round with the raising of $27 million. Proceeds will be used to advance development of the Company's proprietary platform technology and commercial programs for non-invasive, fluid-based molecular diagnostics in oncology, neurodegenerative diseases and other clinical areas.

11 Mar 2014

Ultra-high-field MRI provides detailed views of brain area implicated in Parkinson's disease

New research shows that ultra-high-field magnetic resonance imaging (MRI) provides detailed views of a brain area implicated in Parkinson's disease, possibly leading to earlier detection of a condition that affects millions worldwide. The results of this research are published online in the journal Radiology.

5 Mar 2014

Eisai collaborates with Biogen Idec to develop and commercialize treatment options for AD

Eisai Co., Ltd. and Biogen Idec announced today that they have entered into a collaboration to develop and commercialize two of Eisai's clinical candidates for Alzheimer's disease (AD), E2609 and BAN2401.

5 Mar 2014

New probes help to quantify normally folded and misfolded conformations of protein in cells

Scientists at The Scripps Research Institute (TSRI) have invented small-molecule folding probes that enable them to quantify functional, normally folded and disease-associated misfolded conformations (shapes) of a protein-of-interest in cells under different conditions.

5 Mar 2014

Stem cells from patients offer model, drug-discovery platform for early-onset form of Alzheimer's

Harvard stem cell scientists have successfully converted skins cells from patients with early-onset Alzheimer's into the types of neurons that are affected by the disease, making it possible for the first time to study this leading form of dementia in living human cells. This may also make it possible to develop therapies far more quickly and accurately than before.

5 Mar 2014

Monell Center announces advocacy program to identify biological causes of smell loss

On Anosmia Awareness Day, the Monell Center announces "A Sense of Hope: The Monell Anosmia Project," a three-year $1.5M fundraising campaign to support a research and advocacy program focused on anosmia, the loss of the sense of smell.

4 Mar 2014

New molecule fluorogenic probe for rapid assessment of individual's risk for Parkinson's disease

A team of researchers from National University of Singapore (NUS) have created the first two-photon, small molecule fluorogenic probe that can serve as a useful tool for the rapid assessment of an individual's potential risk for Parkinson's disease.

3 Mar 2014

Genervon's GM604 bio-drug receives FDA orphan drug designation for ALS treatment

Genervon Biopharmaceuticals announced today that the U.S. Food and Drug Administration has granted an "orphan drug" designation to Genervon's GM604 (a.k.a. GM6) bio-drug for the treatment of Amyotrophic Lateral Sclerosis (ALS). The FDA also granted GM604 a "fast-track" designation for ALS in 2013.

3 Mar 2014

Neurodegenerative Diseases News and Research

Expert in gene therapy joins The Children's Hospital of Philadelphia

EMD Serono collaborates with Pfizer and Broad Institute

Aspartic acid in hippocampus may be biomarker for predicting occurrence of cognitive dysfunction

Biogen Idec's ALPROLIX receives FDA approval for hemophilia B treatment

Researchers review influence of lipid rafts on progression of Alzheimer's disease

Genable Technologies, Spark Therapeutics to advance novel therapy for rare form of retinitis pigmentosa

Biogen Idec's ALPROLIX gets Health Canada approval for hemophilia B

New treatment could halt progression of dementia

University of Chicago/ MBL announce first two recipients of Frank R. Lillie Research Innovation Awards

Exosome Diagnostics closes Series B financing round with the raising of $27 million

Ultra-high-field MRI provides detailed views of brain area implicated in Parkinson's disease

Eisai collaborates with Biogen Idec to develop and commercialize treatment options for AD

New probes help to quantify normally folded and misfolded conformations of protein in cells

Stem cells from patients offer model, drug-discovery platform for early-onset form of Alzheimer's

Monell Center announces advocacy program to identify biological causes of smell loss

New molecule fluorogenic probe for rapid assessment of individual's risk for Parkinson's disease

Genervon's GM604 bio-drug receives FDA orphan drug designation for ALS treatment

Max Planck scientists identify new mechanisms in cellular stress response

Heat shock protein may be involved in folding processes of tau protein

Researchers discover how brain cells change during learning and memories

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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