Neurodegenerative Diseases News and Research

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Pulsating blood vessels drive brain waste clearance during sleep

The word "brainwashing" usually triggers negative associations. But our brain health for sure depends on it. Scientists at the University of Oslo have recently made new and important discoveries about how and why this happens when we are sleeping.

30 Mar 2023

The connection between gut microbiota, the gut–brain axis, and brain aging: can polyphenols have an impact?

A review published in the Antioxidants journal aimed to understand the impact of gut microbiota on brain aging.

28 Mar 2023

Computational approach used to understand the mechanisms of protein folding in tauopathies

A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases.

27 Mar 2023

Genes known to control eye color are essential for retinal health

Metabolic pathways consist of a series of biochemical reactions in cells that convert a starting component into other products.

23 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Increased intake of magnesium-rich foods could help reduce dementia risk

More magnesium in our daily diet leads to better brain health as we age, according to scientists from the Neuroimaging and Brain Lab at The Australian National University (ANU).

23 Mar 2023

Designer DNA drug could be used to delay paralysis in ALS

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

17 Mar 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

15 Mar 2023

Innate immune molecule could be at the root of ALS

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures.

13 Mar 2023

Active disease process in early CTE differs substantially from late-stage disease

Millions of people, including athletes who play contact sports, members of the military and victims of domestic violence, are exposed to repetitive head impacts (RHI), which is the primary risk factor for developing chronic traumatic encephalopathy (CTE).

13 Mar 2023

Abnormally low autoantibody activity significantly associated with autism severity

A recent study hypothesized a dysfunction of the self-recognition properties of the immune system in autism.

13 Mar 2023

Microglia partner with T cells to cause neurodegeneration, study shows

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

8 Mar 2023

Study finds no association between gout and neurodegenerative diseases in the general population

A study published in Scientific Reports highlights that gout can increase the risk of Alzheimer’s disease and Parkinson’s disease in younger or overweight individuals. The study was conducted in a representative Korean population.

8 Mar 2023

Biologists discover how to awaken and reactivate neural stem cells

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons.

1 Mar 2023

Using vitamin B5 supplementation to boost red blood cell production in people with myelodysplastic syndromes

Scientists from Barts Cancer Institute at Queen Mary University of London and the Francis Crick Institute, have uncovered why patients with a rare type of blood cancer suffer from ineffective red blood cell production, and how vitamin B5 could be combined with existing drugs to improve outcomes.

1 Mar 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

Three intestinal bacteria associated with dementia with Lewy bodies discovered

Dementia with Lewy bodies (DLB), one of the most common forms of dementia, has no cure. Previous studies suggested that gut bacteria, the microorganisms that live in the human digestive tract, play a role in Parkinson's disease, another neurodegenerative disorder, but the bacteria involved in DLB had not been identified.

28 Feb 2023

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

A team of international scientists has recently characterized the structure of tumor necrosis factor receptor associated factor 6 (TRAF6) N-terminal domain for therapeutic purposes.

28 Feb 2023

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Nearly 100% of cases of amyotrophic lateral sclerosis-;the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease -; involve the buildup of a protein called TDP-43.

27 Feb 2023

Young people with good sleep habits less likely to die early

Getting good sleep can play a role in supporting your heart and overall health-;and maybe even how long you live-;according to new research being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

23 Feb 2023

Neurodegenerative Diseases News and Research

Pulsating blood vessels drive brain waste clearance during sleep

The connection between gut microbiota, the gut–brain axis, and brain aging: can polyphenols have an impact?

Computational approach used to understand the mechanisms of protein folding in tauopathies

Genes known to control eye color are essential for retinal health

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Increased intake of magnesium-rich foods could help reduce dementia risk

Designer DNA drug could be used to delay paralysis in ALS

High consumption of common artificial sweetener lowers activation of T-cells in mice

Innate immune molecule could be at the root of ALS

Active disease process in early CTE differs substantially from late-stage disease

Abnormally low autoantibody activity significantly associated with autism severity

Microglia partner with T cells to cause neurodegeneration, study shows

Study finds no association between gout and neurodegenerative diseases in the general population

Biologists discover how to awaken and reactivate neural stem cells

Using vitamin B5 supplementation to boost red blood cell production in people with myelodysplastic syndromes

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

Three intestinal bacteria associated with dementia with Lewy bodies discovered

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Young people with good sleep habits less likely to die early

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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