Neurodegenerative Disorder News and Research

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BGU researchers redesign portion of FDA-approved drug into new molecule to treat ALS

Ben-Gurion University of the Negev researchers are developing a new therapy for Amyotrophic Lateral Sclerosis using part of an existing FDA-approved drug that restores the central nervous system's (CNS) immune defenses and increases life expectancy.

25 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Huntington's disease is a neurodegenerative disorder that causes patients to lose their ability to move, speak, and even think. It is caused by a gene mutation that produces an abnormal form of the protein huntingtin, which aggregates and builds up inside neurons of the cortex and striatum.

23 Mar 2017

Study: Unsaturated fatty acid metabolism associated with progression of Alzheimer's disease

A new study published in PLOS Medicine's Special Issue on Dementia has found that the metabolism of omega-3 and omega-6 unsaturated fatty acids in the brain are associated with the progression of Alzheimer's disease.

22 Mar 2017

Researchers discover cellular defects that underlie familial form of Parkinson's disease

Howard Hughes Medical Institute researchers have introduced a genetic mutation found in some patients with early onset Parkinson's disease into mice, creating a new animal model of the disease.

14 Mar 2017

Discovery of early biomarkers paves way for new insight into Huntington's disease

Early warning signs of Huntington's disease have been uncovered in a sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study in Scientific Reports has found.

22 Feb 2017

Researchers unlock specific mechanisms behind Aβ-induced cytoxicity in Alzheimer's disease

Alzheimer's disease is a progressive neurodegenerative disorder that leads to dementia via advanced neuronal dysfunction and death. A person with Alzheimer's disease suffers loss of control over thought, memory and language abilities.

14 Feb 2017

New infusion therapy may help avoid debilitating symptoms in Parkinson's disease patients

Constant infusion of a drug now used intermittently to "rescue" patients with Parkinson's from bouts of immobility may also help avoid these debilitating symptoms and smooth out their movement throughout the day, physician-scientists say.

14 Feb 2017

Selonterra publishes article on novel APOE4 mechanism linked to Alzheimer’s disease

Selonterra LLC, a biotechnology company discovering therapies for Alzheimer’s disease and Parkinson’s disease announced the publication of the article “Identification of a Nuclear Respiratory Factor 1 Recognition Motif in the Apolipoprotein E Variant APOE4 linked to Alzheimer’s Disease” in Scientific Reports, a peer-reviewed journal of the Nature Publishing Group.

19 Jan 2017

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

A new Tel Aviv University study finds that a popular food supplement called phosphatidylserine may be instrumental in reversing the detrimental effects of Familial Dysautonomia (FD), a debilitating neurodegenerative disorder that affects approximately 1 in 31 Jewish people of Eastern European, or Ashkenazi, ancestry.

21 Dec 2016

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

A new technique offers better sensitivity and accuracy in detecting an essential biomarker of cancer and inflammatory diseases.

7 Dec 2016

HD is myopathy as well as neurodegenerative disease, study suggests

Researchers have discovered that mice with Huntington's disease (HD) suffer defects in muscle maturation that may explain some symptoms of the disorder.

29 Nov 2016

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

According to a recent study published in JAMA Neurology, Northwestern Medicine scientists have examined more than a century of data of the genetic makeup of ataxias, a neurodegenerative disorder, to better understand the different forms of this devastating disease and how it affects patients.

8 Nov 2016

Stanford researchers discover new biological markers to measure progression of Huntington's disease

Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease (HD).

7 Nov 2016

Fruits, vegetables rich in antioxidants and carotenoids linked to better function in ALS patients

New research at Columbia University's Mailman School of Public Health reveals that foods like fruits and vegetables that are high in antioxidant nutrients and carotenoids are associated with better function in amyotrophic lateral sclerosis (ALS) patients around the time of diagnosis.

1 Nov 2016

Brain atrophy patterns linked to loss of specific cognitive abilities in patients with Alzheimer's disease

Mathematical modeling of the brain scans of patients with Alzheimer's disease and others at risk for the devastating neurodegenerative disorder has identified specific patterns of brain atrophy that appear to be related to the loss of particular cognitive abilities.

8 Oct 2016

Experimental drug may prevent development of multiple sclerosis in mice

The experimental drug laquinimod may prevent the development or reduce the progression of multiple sclerosis (MS) in mice, according to research published in the September 21, 2016, online issue of Neurology Neuroimmunology & Neuroinflammation, a medical journal of the American Academy of Neurology.

21 Sep 2016

Neurodegenerative Disorder News and Research

BGU researchers redesign portion of FDA-approved drug into new molecule to treat ALS

Easing cellular traffic jams in Huntington’s disease may save brain cells

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Study: Unsaturated fatty acid metabolism associated with progression of Alzheimer's disease

Researchers discover cellular defects that underlie familial form of Parkinson's disease

Discovery of early biomarkers paves way for new insight into Huntington's disease

Researchers unlock specific mechanisms behind Aβ-induced cytoxicity in Alzheimer's disease

New infusion therapy may help avoid debilitating symptoms in Parkinson's disease patients

Selonterra publishes article on novel APOE4 mechanism linked to Alzheimer’s disease

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

New chemosensor offers better sensitivity in detecting biomarker for cancer and inflammatory diseases

HD is myopathy as well as neurodegenerative disease, study suggests

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

Stanford researchers discover new biological markers to measure progression of Huntington's disease

Fruits, vegetables rich in antioxidants and carotenoids linked to better function in ALS patients

Brain atrophy patterns linked to loss of specific cognitive abilities in patients with Alzheimer's disease

Experimental drug may prevent development of multiple sclerosis in mice

HMS study reveals key instigator of nerve cell damage in ALS patients

Scientists examine how neural responses change over time in patients with Parkinson's disease

Study finds risk markers for Parkinson's disease hiding in unusual spots

Aneuro: A Year of Neuroscience in Review eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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