Neurological Disease News and Research

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Blue-green algae linked to Alzheimer's disease

An international team of researchers, including scientists from the University of Dundee have announced that cyanobacteria (blue-green algae) found throughout the world may produce a toxin linked to certain types of neurological disease.

5 Apr 2005

Solving sleep problems helps epileptic children

Sleeping woes may explain why children with epilepsy are often so hyperactive, say researchers with the University of Florida's Evelyn F. and William L. McKnight Brain Institute.

30 Mar 2005

Researchers have identified the proteins that allow specific brain cells to "change channels"

Johns Hopkins researchers have identified the proteins that allow specific brain cells to "change channels," a rare ability that tweaks what can come into the cell. The findings, described in the March 24 issue of Neuron, might let researchers harness the process, perhaps one day using it to protect cells that die in Lou Gehrig's disease.

28 Mar 2005

Major milestone in identifying and creating a register of genes involved in multiple sclerosis

For the first time in this disease area, researchers at the SGI have identified 80 genes involved in the inflammatory and neuro-degenerative pathways of MS, based on a 40% genome scan comparing the genetic profile of a total of 1,800 people with MS and healthy individuals in different populations.

17 Mar 2005

RNA interference as promising therapy for ALS

Scientists at the Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have used RNA interference in transgenic mice to silence a mutated gene that causes inherited cases of amytrophic lateral sclerosis (ALS), substantially delaying both the onset and the progression rate of the fatal motor neuron disease.

13 Mar 2005

First comprehensive examination of strenuous physical activity and the risk of developing Parkinson's disease

In the first comprehensive examination of strenuous physical activity and the risk of developing Parkinson's disease, researchers from the Harvard School of Public Health (HSPH) have found that men who exercised regularly and vigorously early in their adult life had a lower risk for developing Parkinson's disease compared to men who did not.

22 Feb 2005

How polychlorinated biphenyls open brain cells to Parkinson's assault

University of Rochester scientists investigating the link between PCBs, pesticides and Parkinson's disease demonstrated new and intricate reactions that occur in certain brain cells, making them more vulnerable to injury after exposures.

9 Feb 2005

Finding points towards the possibility of retrovirus involvement in ALS (amyotrophic lateral sclerosis)

A significant proportion of patients suffering from ALS (amyotrophic lateral sclerosis), also known as Lou Gehrig's disease or motor neuron disease, have a marker of retrovirus activity in their blood, reports the February 8 issue of the medical journal Neurology.

7 Feb 2005

Breakthrough in identifying causes and treatment for degenerative neurological diseases

A new, high resolution x-ray scanning technique that can look inside a single brain tissue cell, is a major step forward in identifying the role of iron and other metals in degenerative neurological diseases such as Alzheimer’s and Parkinson’s.

24 Jan 2005

Researchers have identified the cellular receptor for the JC virus

Researchers funded in part by the National Institute of Neurological Disorders and Stroke (NINDS) have identified the cellular receptor for the JC virus, which causes the fatal neurological disease progressive multifocal leukoencephalopathy (PML).

17 Jan 2005

Antibiotics protect nerves in mice by turning on genes

A family of antibiotics that includes penicillin may help prevent nerve damage and death in a wide variety of neurological diseases, including Lou Gehrig's disease, dementia, stroke, and epilepsy, Johns Hopkins researchers have found.

6 Jan 2005

Researchers can now inexpensively program the chemical synthesis of entire genes on a single microchip

Devices the size of a pager now have greater capabilities than computers that once occupied an entire room. Similar advances are being made in the emerging field of synthetic biology at the University of Houston, now allowing researchers to inexpensively program the chemical synthesis of entire genes on a single microchip.

23 Dec 2004

Rett Syndrome, the first identified epigenetic disease - linked to specific defects in the three-dimensional folding of chromatin

Sometime between the age of 6 and 18 months, after a period of seemingly normal development, girls affected with Rett Syndrome lose interest in play; they gradually become withdrawn and anxious, develop autistic-like behaviors, and acquire specific symptoms like repetitive teeth-grinding and hand-wringing.

20 Dec 2004

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Using hairlike microelectrodes and computer analysis, neurobiologists at Duke University Medical Center have demonstrated that they can see the detailed instant-to-instant electrical "brainscape" of neural activity across a living brain.

8 Dec 2004

Study suggests safer immunization approach to Alzheimer's

Researchers at the University of Illinois at Chicago have had preliminary success with a method of immunization intended to dissolve the plaques in brain tissue that are associated with Alzheimer's disease.

28 Oct 2004

New oral vaccine treatment is effective in reducing Alzheimer's disease pathology

Alzheimer's disease is characterized by progressive loss of cognitive function due to amyloid-beta (Aß) deposits in the central nervous system. If these deposits could be stopped or slowed, Alzheimer's disease might become more manageable.

25 Oct 2004

Human primitive spinal cord cells may delay symptoms and paralysis associated with Lou Gehrig's disease

Human primitive spinal cord cells delayed symptoms and paralysis by a week when implanted in the spinal cord of rats destined to develop amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, researchers from Johns Hopkins report.

24 Oct 2004

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Brain cells become increasingly unable to regulate calcium loads as they age, becoming more vulnerable to injury and premature death, according to new findings that Virginia Commonwealth University researchers will present at an international conference this month.

20 Oct 2004

Robotic microscope shows how mutant Huntington's disease protein affects neurons

Using a specially designed robotic microscope to study cultured cells, researchers have found evidence that abnormal protein clumps called inclusion bodies in neurons from people with Huntington's disease (HD) prevent cell death.

13 Oct 2004

A novel gene therapy strategy may help reduce seizures in adults suffering from epilepsy

Deborah Lin, from the Faculty of Medical and Health Sciences, is investigating the effects of a therapeutic gene transfer in a particular form of epilepsy which affects the brain’s temporal lobe region.

12 Oct 2004