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Levodopa and pramipexole appear to be reasonable options as initial therapy for Parkinson disease

An article in the July issue of the Archives of Neurology reports that the drugs levodopa and pramipexole both appear to be reasonable options as initial therapy for Parkinson disease, but they are associated with different efficacy and adverse effects.

20 Jul 2004

Novel tool that can be used to visualize single neurons in living brain tissue

Carnegie Mellon University neuroscientist Alison Barth has developed the first tool to identify and study individual neurons activated in a living animal.

15 Jul 2004

New hereditary spastic paraplegia research

In work reported this week, researchers have taken our understanding of HSP to a new level with the development of an animal model for the disease.

13 Jul 2004

Possible cure for sudden infant death syndrome (SIDS)

University of Chicago researchers may have found a crucial clue to understanding and ultimately eliminating sudden infant death syndrome, the leading cause of post-neonatal mortality in the United States.

9 Jul 2004

Mitochondria in spinal cords is Lou Gehrig’s disease target according researchers

The selective killing of spinal cord neurons in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, occurs when tiny cellular components called mitochondria actively recruit a mutant disease-causing protein into specific neuron cells, according to new research by University of California, San Diego (UCSD) School of Medicine investigators.

9 Jul 2004

Identification of a naturally occurring genetic difference that controls the production of serotonin in the brain

Researchers at Duke University Medical Center have provided the first direct evidence in mice for the role of an enzyme that specifically controls the production of serotonin in the brain.

8 Jul 2004

Researchers shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease

CNRS and Inserm research scientists at the Institut Curie have shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease.

8 Jul 2004

Research to unravel exactly what is going on chemically, when Alzheimer's sets in

Science understands Alzheimer's disease as the progressive decline of a particular region of the brain. But the underlying mechanisms leading to this decline are still very much a mystery.

7 Jul 2004

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

Scientists at The Scripps Research Institute have described the regulatory mechanism of an important human protein called Rac that controls a number of biological processes and is directly implicated in several human diseases.

2 Jul 2004

Positron emission tomography offers a better way to observe the damage that strokes and neurodegenerative diseases wreak on brain cells

A laser-based microscopy technique may have settled a long-standing debate among neuroscientists about how brain cells process energy

2 Jul 2004

A Center for Human Genetics/Genomics has been established at the University of California

Established in UCSD Health Sciences, which includes the School of Medicine and School of Pharmacy and Pharmaceutical Sciences, the Center brings together UCSD faculty from multiple campus departments and schools including medicine, pharmacy, biology, biostatistics and mathematics.

30 Jun 2004

Michael J. Fox Foundation funds $2 million to solve midbrain system mysteries

The Michael J. Fox Foundation for Parkinson's Research (MJFF) announced today that it has awarded approximately $2.1 million to fund 11 research projects

29 Jun 2004

Discovery of gene that causes a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS)

The discovery of the Senataxin gene, on chromosome 9q34, may provide clues to the mechanisms of related brain disorders. The study appears in the June 2004 issue of the American Journal of Human Genetics.

28 Jun 2004

Experimental therapy improves arm function in chronically impaired stroke survivors

An experimental therapy improves arm function in chronically impaired stroke survivors long after the possibility of spontaneous recovery has been exhausted, researchers reported today at the 5th World Stroke Congress.

26 Jun 2004

Research suggests the brain is a much more sensitive organ than originally perceived, sensitive to the tiniest of chemical signals

The brain is a maddeningly complex organ for scientists to understand. No assumption can remain unchallenged, no given taken as a given.

24 Jun 2004

Fat hormone leptin affects a specific type of target neurons in the brain

Nina Balthasar and her colleagues have presented direct evidence that the fat hormone leptin affects a specific type of target neurons in the brain -- a prime link in the brain's regulation of the body's energy balance.

24 Jun 2004

New clues into the mystery of the brain’s ultra-complicated cells known as neurons

Researchers from USC and the Technion Medical School in Israel have uncovered new clues into the mystery of the brain’s ultra-complicated cells known as neurons.

16 Jun 2004

Artificial vibration has potential to help stroke patients recover their mobility more quickly

By artificially vibrating certain muscle parts, the brain areas and neuronal pathways responsible for movement can be trained. This has the potential to help stroke patients recover their mobility more quickly. These are the results of PhD research by Maarten Steyvers of the Department of Kinesiology, K.U.Leuven.

15 Jun 2004

Significant vaccine advance for Parkinson’s disease therapy

Scientists at the University of Nebraska Medical Center in Omaha and Columbia University Medical Center in New York have discovered a new vaccine approach that successfully prevents the death of brain cells in a mouse model of Parkinson’s disease.