Neurons News and Research

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Study uncovers missing piece in the complex nerve-network needed for left-right turns

Have you ever wondered what happens in the brain when we move to the right or left? Most people don't; they just do it without thinking about it. But this simple movement is actually controlled by a complex process.

12 Feb 2024

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) – the biggest genetic risk factor for late-onset Alzheimer's disease.

9 Feb 2024

Amputees regain temperature sensation with new prosthetic technology

Sensory feedback is important for amputees to be able to explore and interact with their environment. Now, researchers have developed a device that allows amputees to sense and respond to temperature by delivering thermal information from the prosthesis' fingertip to the amputee's residual limb.

9 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

8 Feb 2024

Enzyme released by immune cells may play role in depression

Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors.

8 Feb 2024

Scientists unlock secrets of the brain's internal compass

Our sense of direction is essential to our ability to navigate the world around us. It acts as the brain's internal compass to help us find our way and, just as importantly, to prompt us to change course when we're heading in the wrong direction.

8 Feb 2024

New treatment target found for CDKL5 deficiency disorder

Scientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.

7 Feb 2024

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

The human brain is an organ that takes nearly from 20 to 25% of the energy the body needs. This high energy demand for neuronal functions depends on the transport and precise distribution of mitochondria — the energy-generating cell organelles — in each neuron.

7 Feb 2024

Odors stimulate specific brain cells involved in rapid decision making

Researchers at the University of Colorado Anschutz Medical Campus have discovered that odors stimulate specific brain cells that may play a role in rapid `go, no-go' decision making.

7 Feb 2024

New link between stress, immune system, and depression discovered

Chronic stress affects the immune system and the brain. UZH researchers now show that a particular enzyme found in cells of the immune system enters the brain under stress.

7 Feb 2024

Study pinpoints a protein linked to metastatic pancreatic cancer

Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed.

7 Feb 2024

Bioprinting breakthrough: Tech platform creates 3D neural tissues in which neurons and glia connect

Researchers produced 3D bioprinted human brain tissues, allowing for the creation of functioning neural networks that could simulate network activity in normal and pathological situations.

6 Feb 2024

Research reveals crucial role of saturated fatty acids in memory creation process

Researchers at the University of Queensland have revealed the crucial role of saturated fatty acids in the brain's consolidation of memories.

5 Feb 2024

Protein may hold key to restoring treatment response in drug-resistant neuroendocrine prostate cancer

It may be possible to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment by depletion of a certain protein in cancer cells.

5 Feb 2024

New approach to treating neuropathic pain offers the possibility of non-opioid pain relief for millions

Researchers investigated the selective activity of sigmoid 2 receptor (σ2R) or transmembrane protein 97 (TMEM97) ligands on murine neuropathic pain models, their effects on nociceptive neurons and the mechanism of action after 24 hours.

5 Feb 2024

bit.bio to showcase its ioCRISPR-Ready CellsTM products at the SLAS 2024 international conference and exhibition

bit.bio, the company coding human cells for novel cures, will showcase recent data and important applications of its new portfolio of ioCRISPR-Ready Cells at the Society for Laboratory Automation and Screening (SLAS) conference.

From Society for Laboratory Automation and Screening (SLAS) 5 Feb 2024

Engrailed-1 protein promotes pancreatic cancer progression and metastasis

Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed.

2 Feb 2024

Study reveals the spatial connectivity patterns of mouse hippocampal neurons

A study published in Science on Feb. 1 reported a comprehensive database of single-neuron projectomes consisting of over 10,000 mouse hippocampal neurons, thus revealing the spatial connectivity patterns of mouse hippocampal neurons at the mesoscopic level.

2 Feb 2024

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

1 Feb 2024

Neurons News and Research

Study uncovers missing piece in the complex nerve-network needed for left-right turns

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

Amputees regain temperature sensation with new prosthetic technology

Rucaparib and its major metabolite exhibit differential biological activity and synergy

New drug targets key mechanism in ALS, protects motor neurons

Enzyme released by immune cells may play role in depression

Scientists unlock secrets of the brain's internal compass

New treatment target found for CDKL5 deficiency disorder

Mitochondria on the move: New discovery could revolutionize treatment of brain diseases

Odors stimulate specific brain cells involved in rapid decision making

New link between stress, immune system, and depression discovered

Study pinpoints a protein linked to metastatic pancreatic cancer

Bioprinting breakthrough: Tech platform creates 3D neural tissues in which neurons and glia connect

Research reveals crucial role of saturated fatty acids in memory creation process

Protein may hold key to restoring treatment response in drug-resistant neuroendocrine prostate cancer

New approach to treating neuropathic pain offers the possibility of non-opioid pain relief for millions

bit.bio to showcase its ioCRISPR-Ready CellsTM products at the SLAS 2024 international conference and exhibition

Engrailed-1 protein promotes pancreatic cancer progression and metastasis

Study reveals the spatial connectivity patterns of mouse hippocampal neurons

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Neuroscience - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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