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New drug could be a game changer for cancer patients undergoing chemotherapy

Cisplatin is a chemotherapy indicated to fight tumors in many types of cancer. However, it does have major side effects – especially kidney toxicity, that can lead to acute kidney failure.

15 Nov 2022

Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

A targeted therapy for children with high-risk Hodgkin lymphoma (HL) was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children's Oncology Group (COG) and led by pediatric oncologists at Roswell Park Comprehensive Cancer Center, Children's Healthcare of Atlanta and Winship Cancer Institute of Emory University. By combining the targeted antibody-drug conjugate (ADC) brentuximab vedotin (BV) with the standard chemotherapy regimen, children were 10% less likely to relapse.

2 Nov 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

New SIO-ASCO practice guideline addresses the use of integrative therapies for cancer pain management

A new joint practice guideline from the Society for Integrative Oncology and the American Society of Clinical Oncology, Inc. has been published to address gaps in healthcare providers' knowledge of how to safely and effectively treat common cancer symptoms and side effects using integrative medicine approaches.

19 Sep 2022

Proactive simple surgical procedure could be effective for treating diabetic foot ulcers

Performing proactive surgery to adjust the mechanics of the foot, appears to be effective to treat diabetic foot ulcers, a common and debilitating complication of diabetes, without the potential complications and at significantly lower cost compared to conservative management.

19 Sep 2022

Using deep learning to guide the selection of chemotherapy after surgery for colorectal cancer patients

Among patients with colorectal cancer spread to lymph nodes, a deep learning marker can identify one-third with excellent prognosis and consequently no need for adjuvant chemotherapy.

30 Aug 2022

The risk of adverse reactions when herbal medications are taken with cancer drugs

A new study discusses phytovigilance initiatives based on the real-world use of herbal drugs in cancer along with conventional chemotherapy.

24 Aug 2022

Medical cannabis patients may not be getting consistent guidance from clinicians, analysis suggests

Due to a lack of publicly available data, understanding what products medical cannabis patients use for various conditions has mostly come from survey responses.

22 Aug 2022

Experts assert the need to amplify "food first" and "no needle" messages among all athletes

Intravenous (IV) nutrition, which used to be considered a treatment of 'last resort', is threatening to become the norm for competitive athletes, despite no scientific evidence that it works or that it is safe, warn experts in an editorial, published online in the British Journal of Sports Medicine.

17 Aug 2022

Cancer-related fatigue contributes to balance problems following exposure to chemotherapy for breast cancer

For many women who have undergone chemotherapy for breast cancer, cancer-related fatigue (CRF) is a persistent side effect – and one that contributes to ongoing balance problems, suggests a paper in Rehabilitation Oncology, official journal of APTA Oncology, an academy of the American Physical Therapy Association (APTA).

15 Aug 2022

Researchers develop wearable technology to measure key brain mechanisms through the skin

Researchers at NYU Tandon have reached a key milestone in their quest to develop wearable technology that manages to measure key brain mechanisms through the skin.

9 Aug 2022

Researchers unravel a novel molecular target of eicosapentaenoic acid

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities.

9 Aug 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

Addition of brentuximab vedotin to chemotherapy has a positive impact for patients with Hodgkin lymphoma

A study led by researchers from Mayo Clinic Comprehensive Cancer Center has found that the addition of brentuximab vedotin to standard chemotherapy treatment improves overall survival in patients with Hodgkin Lymphoma, when compared to the current standard of chemotherapy alone.

14 Jul 2022

Study characterizes long-COVID symptoms in hospitalized and non-hospitalized COVID-19 patients

Scientists have provided a detailed overview on the long-term symptoms experienced by COVID-19 patients after initial primary infection with SARS-CoV-2.

30 Jun 2022

Microfluidics-enabled soft robotic prosthetics show promise to reduce skin ulcerations, pain in amputees

Every 30 seconds, a leg is amputated somewhere in the world due to diabetes. These patients often suffer from neuropathy, a loss of sensation in the lower extremities, and are therefore unable to detect damage resulting from an ill-fitting prosthesis, which leads to the amputation of a limb.

28 Jun 2022

Study reveals the benefits of using thalidomide in patients with severe arteriovenous malformations

The same properties that caused birth defects when it was given to pregnant women, the inhibition of blood vessel formation (anti-angiogenesis), have led to an interest in thalidomide's therapeutic utility in other fields.

10 Jun 2022

Height increases risk of certain diseases

In a recent study published in the Journal PLoS Genetics, researchers investigated how height determined several common clinical traits in adults by comparing associations of those traits with actual- and genetically-predicted-height.

5 Jun 2022

Genetically predicted height linked to risk for several common health conditions

A large genetic study by the U.S. Department of Veteran Affairs' Million Veteran Program (MVP)) has found that a person's height may affect their risk for several common health conditions in adulthood.

2 Jun 2022

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose. LHON affects the optic nerve, which carries visual signals from the light-sensing retina to the brain.

1 Jun 2022