Neuroscience News and Research

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Investigational Insomnia Medicine from Merck improved patients’ ability to fall and stay asleep according to new phase III Data

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced new data from two pivotal Phase III efficacy trials for suvorexant, the investigational medicine Merck is developing for the treatment of insomnia. In the studies, suvorexant significantly reduced the time it took patients to fall asleep and increased the time that patients stayed asleep as early as the first night and at the three-month time point compared to placebo. The investigational medicine met statistical significance for all primary endpoints except for one measurement at Month 3 in one of the trials. These late-breaking data were presented here today at SLEEP 2012, the 26th Annual Meeting of the Associated Professional Sleep Societies.

13 Jun 2012

A father's love contributes more to a child's development

A father's love contributes as much - and sometimes more - to a child's development as does a mother's love. That is one of many findings in a new large-scale analysis of research about the power of parental rejection and acceptance in shaping our personalities as children and into adulthood.

13 Jun 2012

Two video articles describe pre-surgical preparation of corneal tissue

Over 45,000 corneal transplant eye surgeries are performed in the US every year. On June 12, 2012, in an effort to standardize this complex procedure, two video articles describing pre-surgical preparation of corneal tissue were published in JoVE, the Journal of Visualized Experiments.

13 Jun 2012

Unique UCLA program proves effective in treating teens with ASD

Teenagers with autism spectrum disorder are in a bind. The disorder is characterized by impairments in communication and social interaction, but it's a continuum, so some teens diagnosed with ASD are considered high functioning and healthy enough to be "mainstreamed" in school.

13 Jun 2012

Gut microbes regulate brain levels of serotonin

UCC scientists have shown that brain levels of serotonin, the 'happy hormone' are regulated by the amount of bacteria in the gut during early life. Their research is being published today in the leading international psychiatry journal, Molecular Psychiatry.

13 Jun 2012

Experimental drug and genetic differences indicate how people deal with fear and stress

Researchers at Duke University and the National Institutes of Health have found a way to calm the fears of anxious mice with a drug that alters their brain chemistry. They've also found that human genetic differences related to the same brain chemistry influence how well people cope with fear and stress.

12 Jun 2012

Changes in walking speed in late life may signal MCI

A new study shows that changes in walking speed in late life may signal the early stages of dementia known as mild cognitive impairment (MCI).

12 Jun 2012

DNDi, Astellas partner on new drug discovery research for treatment of NTDs

Astellas Pharma Inc. and the Drugs for Neglected Diseases initiative (DNDi) announced an agreement today to collaborate on drug discovery research for leishmaniasis, Chagas disease, and sleeping sickness - three neglected tropical diseases (NTDs) which together affect nearly 10 million people worldwide.

12 Jun 2012

Updated AAN guideline outlines treatments for infantile spasms

The American Academy of Neurology has issued an updated guideline outlining the best treatments for infantile spasms, a rare type of seizure that can occur in infants and young children.

12 Jun 2012

Researchers demonstrate effectiveness of a potential new therapy for stroke patients

Researchers at the University of Missouri have demonstrated the effectiveness of a potential new therapy for stroke patients in an article published in the journal Molecular Neurodegeneration. Created to target a specific enzyme known to affect important brain functions, the new compound being studied at MU is designed to stop the spread of brain bleeds and protect brain cells from further damage in the crucial hours after a stroke.

12 Jun 2012

Sucrose and menthol act independently to reduce coughing

Millions of Americans reach for their cough drops or syrup at the first sign of a cough. However, scientists are unsure if and how these popular remedies work. Now, new findings from the Monell Center suggest that sucrose and menthol, ingredients commonly regarded as flavorings in these preparations, each act independently to reduce coughing.

12 Jun 2012

ABM treatments can address childhood anxiety

According to the Anxiety and Depression Association of America, one in eight children suffers from an anxiety disorder. And because many anxious children turn into severely anxious adults, early intervention can have a major impact on a patient's life trajectory. The understandable reluctance to use psychiatric medications when it comes to children means child psychologists are always searching for viable therapeutic alternatives.

12 Jun 2012

Mutation responsible for rare, hereditary motor neuron disease disrupts vital links

Studying how nerve cells send and receive messages, Johns Hopkins scientists have discovered new ways that genetic mutations can disrupt functions in neurons and lead to neurodegenerative disease, including amyotrophic lateral sclerosis (ALS).

11 Jun 2012

Dapagliflozin more effective than sitagliptin for adult patients with type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced results from a Phase 3 clinical study that showed the investigational compound dapagliflozin 10 mg demonstrated significant reductions in blood sugar levels (glycosylated hemoglobin levels, or HbA1c) compared with placebo at 24 weeks when either agent was added to existing sitagliptin therapy (with or without metformin) in adult patients with type 2 diabetes.

11 Jun 2012

VHC extends Obstetrics services to Kaiser Permanente members

Virginia Hospital Center announced today an expansion of services offered at Virginia Hospital Center, to include Obstetrics for Kaiser Permanente's members.

11 Jun 2012

Piramal to present data on several molecular imaging compounds at SNM annual meeting

Piramal Imaging SA, a subsidiary of Piramal Healthcare Limited, will present data on several compounds from its molecular imaging portfolio at the Society of Nuclear Medicine's 59th annual meeting in Miami Beach, Fla., from June 9 - 13.

10 Jun 2012

Concussion victims have unique spatial patterns of brain abnormalities that change over time

Patients vary widely in their response to concussion, but scientists haven't understood why. Now, using a new technique for analyzing data from brain imaging studies, researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found that concussion victims have unique spatial patterns of brain abnormalities that change over time

8 Jun 2012

BRF to fund research that focuses on sports-related concussive injuries among young children

The Brain Research Foundation (BRF) today announced it will fund research that aims to improve pediatricians' ability to evaluate and manage sports-related concussive injuries among young children, and guide future research regarding the diagnosis, treatment and long term effects of these events.

7 Jun 2012

Study describes how seizures in people with AS could be linked to brain cell activity imbalance

New research by scientists at the University of North Carolina School of Medicine may have pinpointed an underlying cause of the seizures that affect 90 percent of people with Angelman syndrome (AS), a neurodevelopmental disorder.

7 Jun 2012

Study determines transgenerational effects of cannabinoid exposure in adolescent female rats

Mothers who use marijuana as teens-long before having children-may put their future children at a higher risk of drug abuse, new research suggests.

6 Jun 2012

Neuroscience News and Research

Investigational Insomnia Medicine from Merck improved patients’ ability to fall and stay asleep according to new phase III Data

A father's love contributes more to a child's development

Two video articles describe pre-surgical preparation of corneal tissue

Unique UCLA program proves effective in treating teens with ASD

Gut microbes regulate brain levels of serotonin

Experimental drug and genetic differences indicate how people deal with fear and stress

Changes in walking speed in late life may signal MCI

DNDi, Astellas partner on new drug discovery research for treatment of NTDs

Updated AAN guideline outlines treatments for infantile spasms

Researchers demonstrate effectiveness of a potential new therapy for stroke patients

Sucrose and menthol act independently to reduce coughing

ABM treatments can address childhood anxiety

Mutation responsible for rare, hereditary motor neuron disease disrupts vital links

Dapagliflozin more effective than sitagliptin for adult patients with type 2 diabetes

VHC extends Obstetrics services to Kaiser Permanente members

Piramal to present data on several molecular imaging compounds at SNM annual meeting

Concussion victims have unique spatial patterns of brain abnormalities that change over time

BRF to fund research that focuses on sports-related concussive injuries among young children

Study describes how seizures in people with AS could be linked to brain cell activity imbalance

Study determines transgenerational effects of cannabinoid exposure in adolescent female rats

Neuroscience - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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