Neuroscience News and Research

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Brain receives information from the ear in a surprisingly orderly fashion

The brain receives information from the ear in a surprisingly orderly fashion, according to a University at Buffalo study scheduled to appear June 6 in the Journal of Neuroscience.

6 Jun 2012

Soy protein may not enhance overall cognitive ability in women

Contrary to earlier reports, a new study suggests that soy protein may not preserve overall thinking abilities in women over the age of 45, but may improve memory related to facial recognition.

5 Jun 2012

Scientists identify rhythmic brain cell firing patterns in the motor cortex

A new model for understanding how nerve cells in the brain control movement may help unlock the secrets of the motor cortex, a critical region that has long resisted scientists' efforts to understand it, researchers report June 3 in Nature.

5 Jun 2012

D-cycloserine may increase response to PTSD psychotherapy

Posttraumatic stress disorder (PTSD) is among the most common, distressing, and disabling medical consequences of combat or other extremely stressful life events. The first-line treatment for PTSD is exposure therapy, a type of behavioral therapy where patients confront their fears in a safe environment. Although it is an effective treatment, many patients still experience symptoms after treatment and there is a relatively high drop-out rate.

5 Jun 2012

Treating adolescents for major depression can also reduce risk of drug abuse

Treating adolescents for major depression can also reduce their chances of abusing drugs later on, a secondary benefit found in a five-year study of nearly 200 youths at 11 sites across the United States.

5 Jun 2012

Scientists discover neural mechanism for conscious perception

When people close their eyes, they can form mental images of things that exist only in their minds. Neuroscientists studying this phenomenon at medical schools in the Texas Medical Center believe that there may be a way to use these mental images to help some of the estimated 39 million people worldwide who are blind.

5 Jun 2012

Seattle Genetics, Agensys announce interim data from ASG-5ME phase I trial on CRPC

Agensys, Inc., an affiliate of Tokyo-based Astellas Pharma Inc., and Seattle Genetics, Inc. today announced interim data from a phase I clinical trial evaluating ASG-5ME for the treatment of castration-resistant prostate cancer.

5 Jun 2012

$Ambit, Astellas commence quizartinib Phase 2b trial in relapsed/refractory AML$

Ambit, Astellas commence quizartinib Phase 2b trial in relapsed/refractory AML

Astellas Pharma Inc. and Ambit Biosciences Corporation today announced the initiation of a Phase 2b open-label clinical trial of quizartinib as monotherapy in patients with relapsed and refractory acute myeloid leukemia (AML) with FLT3-ITD mutations.

5 Jun 2012

Results from Janssen's ZYTIGA plus prednisone Phase 3 study on mCRPC

Results observed from pre-specified interim analyses of the randomized, placebo-controlled Phase 3 study, COU-AA-302, demonstrated that patients with metastatic castration-resistant prostate cancer (mCRPC) treated with abiraterone acetate (ZYTIGA) plus prednisone showed a statistically significant improvement in radiographic progression-free survival (rPFS) and all secondary endpoints compared to patients treated with placebo plus prednisone.

4 Jun 2012

Scientists propose new theory of the brain activity behind arm movements

Unlike their visual cousins, the neurons that control movement are not a predictable bunch. Scientists working to decode how such neurons convey information to muscles have been stymied when trying to establish a one-to-one relationship between a neuron's behavior and external factors such as muscle activity or movement velocity.

4 Jun 2012

Initial data to construct first whole-brain wiring diagram of vertebrate brain

Neuroscientists at Cold Spring Harbor Laboratory (CSHL) reached an important milestone today, publicly releasing the first installment out of 500 terabytes of data so far collected in their pathbreaking project to construct the first whole-brain wiring diagram of a vertebrate brain, that of the mouse.

2 Jun 2012

ZYTIGA Phase 3 study for metastatic prostate cancer presented at 48th ASCO

New data presented this weekend at the 48th annual meeting of the American Society of Clinical Oncology (ASCO) showed ZYTIGA (abiraterone acetate) may prove to be an important new treatment option for metastatic prostate cancer patients prior to receiving chemotherapy.

2 Jun 2012

Akron General Medical Center to install Brainsuite iMRI and iCT integrated neurosurgical suites

Brainlab, a manufacturer of software-driven systems for targeted, less-invasive medical treatments, announced today that Akron General Medical Center will install both Brainsuite iMRI and iCT, making it one of only a handful of hospitals in the world to offer both solutions.

2 Jun 2012

JSUMC completes first procedure with TAVR

Jersey Shore University Medical Center proudly announces the completion of its first procedure with the Transcatheter Aortic Valve Replacement (TAVR), the latest minimally-invasive, life-saving innovation for non-operative patients with critical aortic stenosis.

1 Jun 2012

Janssen submits canagliflozin NDA with FDA for treatment of type 2 diabetes

Janssen Research & Development, LLC (Janssen), announced today that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for the use of canagliflozin, an investigational, oral, once-daily, selective sodium glucose co-transporter 2 (SGLT2) inhibitor, for the treatment of adult patients with type 2 diabetes.

1 Jun 2012

Einstein receives NIH grant to create new vaccine against TB

The National Institutes of Health (NIH) has awarded researchers at Albert Einstein College of Medicine at Yeshiva University a five-year, $5.9 million grant to develop a new vaccine against tuberculosis (TB), including the toughest-to-treat forms of the disease known as multi drug-resistant and extensively drug-resistant. The grant will build on a new approach to TB vaccine design that is based on genetically altered Mycobacterium smegmatis, which is closely related to the bacterial species (Mycobacterium tuberculosis) that causes TB in humans.

1 Jun 2012

New method can solve 3-D structures of integral membrane proteins

A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets for new therapies, according to a paper published May 20 in Nature Methods.

31 May 2012

Kona Medical raises $30 million in Series C financing

Kona Medical, Inc. today announced it has raised $30 million in Series C financing to advance its novel hypertension therapy.

31 May 2012

AAPS honors Morphotek with 2012 Excellence in Ligand Binding Assays Award

Morphotek, Inc., a subsidiary of Eisai Inc., announced today that The American Association of Pharmaceutical Scientists (AAPS) has awarded its 2012 Excellence in Ligand Binding Assays Award to the Bioanalytical Development group from Morphotek for their abstract, "Development and Validation of a Pharmacokinetic Assay on the Gyrolab Platform for Use in Phase II/III Clinical Studies."

31 May 2012

Study reveals new evidence of trans-cranial bright light's effect to brain functions

A recent placebo-controlled study reveals new evidence of trans-cranial bright light's effect to brain functions when administered through the ear. Bright light stimulation was found to increase activity in brain areas related to processing of visual sensory information and tactile stimuli. The findings constitute the first ever published scientific article about functional modulation of the brain with bright light delivered to the brain through the ears. The study was published today May 29th, 2012 in the World Journal of Neuroscience.

30 May 2012