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Reata, Abbott partner to develop and commercialize AIMs for chronic diseases

Abbott and Reata Pharmaceuticals today announced that they have entered into a worldwide collaboration to jointly develop and commercialize Reata's portfolio of second-generation oral antioxidant inflammation modulators.

12 Dec 2011

Scientists identify importance of novel protein-regulating mechanism

For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes from cell metabolism to programmed cell death. Now, scientists from the Florida campus of The Scripps Research Institute have identified the importance of a novel protein-regulating mechanism -- called sulfenylation -- that is similar to phosphorylation and may, in fact, open up opportunities to develop new types of drugs for diseases such as cancer.

12 Dec 2011

New method for detailed analyses of electrical activity in brain

Researchers at the Norwegian University of Life Sciences (UMB) and Forschungszentrum J-lich in Germany have developed a new method for detailed analyses of electrical activity in the brain.

12 Dec 2011

New cancer research findings presented at 53rd ASH annual meeting

Researchers from Seidman Cancer Center at University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine presented new research findings in 25 presentations this weekend at the 53rd Annual Meeting of the American Society of Hematology (ASH) at the San Diego Convention Center.

12 Dec 2011

Washington Hospital opens Central Utility Plant

Washington Hospital, the local provider of healthcare for the Tri-City area and one of the region's best medical facilities, today opened a state of the art Central Utility Plant that will provide energy for the campus' expansion and modernization for decades to come.

12 Dec 2011

Increased sensitivity to low frequency vibration found in people with inherited hearing loss

People with a certain form of inherited hearing loss have increased sensitivity to low frequency vibration, according to a study by Professor Thomas Jentsch of the Leibniz-Institut f-r Molekulare Pharmakologie (FMP)/Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch and Professor Gary Lewin (MDC), conducted in cooperation with clinicians from Madrid, Spain and Nijmegen, the Netherlands.

9 Dec 2011

Study: Hearing and sight are deeply intertwined

Our senses of sight and hearing work closely together, perhaps more than people realize, a new UCLA psychology study shows.

9 Dec 2011

Young football players may be at higher risk for stroke

Young football players may be at higher risk for stroke, according to a new study released in Journal of Child Neurology (JCN), published by SAGE.

9 Dec 2011

Pharmacyclics, Janssen partner to develop and market PCI-32765 anti-cancer compound

Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced today that it has executed an agreement with Pharmacyclics, Inc. to jointly develop and market the anti-cancer compound, PCI-32765.

9 Dec 2011

Treating 'brain tsunamis' could stop many victims of major head injury from further damage

Treating 'brain tsunamis' or 'killer waves' could stop many victims of major head injury from suffering additional brain damage, a study published in Lancet Neurology has found.

8 Dec 2011

Animal study offers insights into possible drug targets to improve memory as we age

Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study in the December 7 issue of The Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.

8 Dec 2011

Scientists discover genetic trigger that makes stem cells differentiate in nose epithelia

University of California, Berkeley, neuroscientists have discovered a genetic trigger that makes the nose renew its smell sensors, providing hope for new therapies for people who have lost their sense of smell due to trauma or old age.

8 Dec 2011

BCX4945 proves effective at clearing malaria infections

An antimalarial agent developed by researchers at Albert Einstein College of Medicine of Yeshiva University proved effective at clearing infections caused by the malaria parasite most lethal to humans - by literally starving the parasites to death. The novel research, carried out on a small number of non-human primates, could bolster efforts to develop more potent therapies against one of the world's leading killers.

8 Dec 2011

PrEP shows promise against HIV infection

A new weapon has emerged to prevent HIV infection. Called pre-exposure prophylaxis, or PrEP, it is a strategy of providing medications to at-risk people before they are exposed to the virus. Having shown great promise in recent phase 3 clinical trials, PrEP may soon be rolled out for public use.

8 Dec 2011

Euthymics presents EB-1020 preclinical data on ADHD at ACNP annual meeting

Euthymics Bioscience, Inc. today announced that it has presented preclinical data demonstrating that EB-1020, a next-generation product candidate for adult attention deficit/hyperactivity disorder (ADHD), may be effective for treating ADHD without the burden of drug abuse liability.

8 Dec 2011

Study shows how mothering can strengthen offspring's immune system in brain

An attentive, nurturing mother may be able to help her children better resist the temptations of drug use later in life, according to a study involving the University of Adelaide.

8 Dec 2011

First realistic 3-D diagram of thalamocortical column in rodent brain

Researchers from the lab of Nobel laureate Bert Sakmann, MD, PhD at the Max Planck Florida Institute (MPFI) are reporting that, using a conceptually new approach and state-of-the-art research tools, they have created the first realistic three-dimensional diagram of a thalamocortical column in the rodent brain.

8 Dec 2011

UH Case Medical Center designated as 'Top Hospital' and leader in quality patient care

University Hospitals Case Medical Center in Cleveland, Ohio is among 65 hospitals nationwide to be designated as a "Top Hospital" and leader in quality patient care by The Leapfrog Group.

7 Dec 2011

UCSF resident to receive 2012 William P. Van Wagenen Fellowship

The William P. Van Wagenen Fellowship Selection Committee has announced Matthew Christopher Tate, MD, as the recipient of the 2012 William P. Van Wagenen Fellowship. Dr. Tate, a resident in neurological surgery at University of California in San Francisco, will commence the fellowship on July 1, 2012.

7 Dec 2011

Scientists understand how nervous system becomes wired during early development

Thanks to a new study of the retina, scientists at UC Santa Barbara have developed a greater understanding of how the nervous system becomes wired during early development.

7 Dec 2011